Protein Alignment trn and lron-1

DIOPT Version :10

• Sequence 1: NP_001261796.1
• Gene: trn / 39491
• FlyBaseID: FBgn0010452
• Length: 751
• Species: Drosophila melanogaster
• Sequence 2: NP_510424.4
• Gene: lron-1 / 181553
• WormBaseID: WBGene00008093
• Length: 607
• Species: Caenorhabditis elegans
• Alignment Length: 532
• Identity: 129/532 - (24%)
• Similarity: 203/532 - (38%)
• Gaps: 96/532 - (18%)

  Fly    57 LNPSIQRLVIKSNKIKTI-DSSIQFYAELTFLDLSSNHLMTIPQRTF-AYQKK--LQEVHLNHNK 117
            |..|::.|.|:.|.|..| .|.:....:|..|.|..|.:..:....| :|..:  |.::.|:.|.
 Worm   106 LENSLEELEIRGNYIDGIPQSGVSILKQLKILSLPDNLIEYVQDNAFLSYHSRDSLLKLDLSANN 170

  Fly   118 IGQISNKTFIGLSAVTVLNLRGNQISELHQGTFTPLLKIEELNLGENRIGYLDPKAFDGLSQLRI 182
            :..|.....:||..::.|:|..|.:||:.......:..:|:|:||.|||..:...:.. |..|:.
 Worm   171 LTAIHPTGLLGLENLSQLSLDKNLLSEIPSQALENIPSLEDLSLGVNRIHTISRNSLP-LPNLKS 234

  Fly   183 LYLDDNALTTVPDPVIFQAMPSLAELFLGMNTLQSIQADAFQDLKGLTRLEL-KGASLRNISHDS 246
            |.|:.|.:..:|.. .|...|.|:.|:||.|.|.||.|..|..:.||..|.: ....:.:|..:.
 Worm   235 LSLEVNQIRLIPSD-SFSETPLLSYLYLGNNLLTSIDASMFLHIGGLKVLSMSNNKDITSIQANG 298

  Fly   247 FLGLQELRI---------------LDLSDNRLDRIPSVGLSKLVRLEQLSLGQNDFEVISEGAFM 296
            .|.:|:.::               |:|.|..:.||....|.|:..::.:.|.:|....||...|.
 Worm   299 KLSVQQFKLCICILAFQHAPSLIRLELFDCSISRIEPKSLQKVQHIQVILLSRNQITRISHDTFS 363

  Fly   297 GLKQLKRLEVNGALRLKRVMTGAFSDNGNLEYLNLSSNKMLLEVQEGALSGLSQLKHVVLKANAL 361
            .|.:|..|:::|. .:..|...|||....|..|:||||::...........|.|.|
 Worm   364 NLPELSELDLSGN-SINAVDDFAFSQLPMLTSLDLSSNRLESLPSNVIYDSLMQKK--------- 418

  Fly   362 TSLAEGLFPWKDLQTLDLSENPLSCDCRVMWLHNLL-----VAKNASQDDVSELLCEFPERLRGE 421
            ||..:        :.|.:..||..||..:|||...|     |...||....::  |..|..|.|.
 Worm   419 TSPVQ--------RKLSIQNNPWRCDKDLMWLRKWLRDNGDVTTAASNSPPAK--CWTPSNLSGL 473

  Fly   422 SLRHLNPAMMGCT-----------------------------HADPRKQALIGALLVGSAATITA 457
            .||..:..:...|                             |.:....||:| |::|....:..
 Worm   474 DLRQTDSKLPHKTTKPPVDQFQYKNQQVTNSNGTSQLGYQNPHTEVNGLALVG-LILGIVLVVFV 537

  Fly   458 LALVL-YRCRH-------KIRETIKGGLWGNSALGRKEREYQKTFCDEDYMSRHQHHPCSLGIHS 514
            ..::| |..|.       |.:..:.|....:|...|.......|...||:     .||.|..
 Worm   538 SCIILGYLMRFIFLSYEAKTKPNVFGSTISSSGCIRNMYGGDGTLVSEDH-----GHPSSAN--- 594

  Fly   515 TFPNTY-TAPHH 525
              .|.| ..|.|
 Worm   595 --NNVYLNRPRH 604

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
trn	NP_001261796.1	leucine-rich repeat	62..80	CDD:275380	6/18 (33%)
		LRR	82..406	CDD:443914	91/347 (26%)
		leucine-rich repeat	84..107	CDD:275380	6/23 (26%)
		leucine-rich repeat	108..131	CDD:275380	6/22 (27%)
		leucine-rich repeat	132..155	CDD:275380	5/22 (23%)
		leucine-rich repeat	156..179	CDD:275380	8/22 (36%)
		leucine-rich repeat	180..204	CDD:275380	6/23 (26%)
		leucine-rich repeat	205..228	CDD:275380	10/22 (45%)
		leucine-rich repeat	229..252	CDD:275380	4/23 (17%)
		leucine-rich repeat	253..276	CDD:275380	7/37 (19%)
		leucine-rich repeat	277..300	CDD:275380	6/22 (27%)
		leucine-rich repeat	301..322	CDD:275380	6/20 (30%)
		leucine-rich repeat	326..350	CDD:275380	7/23 (30%)
		leucine-rich repeat	351..373	CDD:275380	3/21 (14%)
		LRRCT	382..434	CDD:214507	17/56 (30%)
lron-1	NP_510424.4	LRR	83..>400	CDD:443914	80/296 (27%)
		leucine-rich repeat	85..109	CDD:275380	1/2 (50%)
		leucine-rich repeat	110..133	CDD:275380	6/22 (27%)
		leucine-rich repeat	134..157	CDD:275380	6/22 (27%)
		leucine-rich repeat	161..184	CDD:275380	6/22 (27%)
		leucine-rich repeat	185..208	CDD:275380	5/22 (23%)
		leucine-rich repeat	209..231	CDD:275380	8/22 (36%)
		leucine-rich repeat	232..255	CDD:275380	6/23 (26%)
		leucine-rich repeat	256..279	CDD:275380	10/22 (45%)
		leucine-rich repeat	280..319	CDD:275380	5/38 (13%)
		leucine-rich repeat	320..343	CDD:275380	7/22 (32%)
		leucine-rich repeat	344..367	CDD:275380	6/22 (27%)
		leucine-rich repeat	368..391	CDD:275380	7/23 (30%)
		leucine-rich repeat	392..410	CDD:275380	6/17 (35%)
		leucine-rich repeat	414..435	CDD:275378	8/37 (22%)
		LRRCT	431..>472	CDD:214507	14/42 (33%)