Protein Alignment trn and egg-6

DIOPT Version :10

• Sequence 1: NP_001261796.1
• Gene: trn / 39491
• FlyBaseID: FBgn0010452
• Length: 751
• Species: Drosophila melanogaster
• Sequence 2: NP_492348.1
• Gene: egg-6 / 172670
• WormBaseID: WBGene00010621
• Length: 961
• Species: Caenorhabditis elegans
• Alignment Length: 760
• Identity: 163/760 - (21%)
• Similarity: 272/760 - (35%)
• Gaps: 208/760 - (27%)

  Fly    31 PPGCQC--------------DDNTLVVQCGEGQLDVLPIALNPSIQRLVIKSNKIKTI---DSSI 78
            |..|.|              |..|:....|..|:|.|.|.....::...:..|.::||   :|::
 Worm    27 PEKCDCKISKSMIILSCNGEDVKTIAQTVGTSQIDELHILNGTDVKIESLPFNGLRTIAILNSTL 91

  Fly    79 QFY---------AELTFLDLSSNHLMTIPQRTFAYQKKLQEVHLNHNKIGQISNKTFIGLSAVT- 133
            |.:         |.:..:.::.|.|.|:|  .|.....|..::||.|:|..|.:|.|.||||:|
 Worm    92 QSFSPTAWRHVEATIEHITINGNELKTVP--VFGNLSTLMSMNLNSNQISSIPDKAFNGLSALTQ 154

  Fly   134 ------------------------------------------------VLNLRGNQISELHQGTF 150
                                                            .|:|..|.|||::....
 Worm   155 LRLENNAICDFPPKSLDAVKASLVLLDVSGNCLDAIPAQILRNAANLMYLDLGSNNISEINNFEL 219

  Fly   151 TPLLKIEELNLGENRIGYLDPKAFDGLSQLRILYLDDNALTTVPDPVIFQAMPSLAELFLGMNTL 215
            ..|..:.||.:..|.:..:.|.||..:.||:.|||.||.::|: |....|...:|..|.:..|.|
 Worm   220 MNLPFLRELRVQNNTLRRIHPMAFMNVPQLQYLYLQDNIISTL-DGNRLQGFKNLEVLDVSNNAL 283

  Fly   216 QSIQADAFQDLKGLTRLELKGASLRNISHDSFLGLQELRILDLSDNRLDRIPSVGLSKLVRLEQL 280
            .::  .:.:||..|.::.:.|..:..|...:|.....|:::.:.:|.:.:|.......|.:|..|
 Worm   284 YAL--PSLKDLPNLKQVRVDGNLITKIETLAFSNNPNLQLISVQNNNIVQISRNSFESLDKLVVL 346

  Fly   281 SLGQNDFEVISEGAFMGLKQLKRLEVNGALRLKRVMTGAFSDNGNLEYLNLSSNKMLLEVQEGAL 345
            .:|.|....|..|.|.|:|.|::|.:... .|..:...:|:...:|..|:|..|| :.:::||..
 Worm   347 LVGNNSLAKIERGMFDGMKNLQQLSIRNN-TLTALDASSFAQLAHLTTLDLGHNK-IHDIEEGTF 409

  Fly   346 SGLSQLKHVVLKANALTSLAEGLFPWKDLQTLDLSENPLSCDCRVMWLHNLLVAKNASQ--DDVS 408
            ..||:|..:.|..|.::.....:|. |.:..:.|..|.|.||.........|:|.....  ....
 Worm   410 DKLSKLFWLDLSNNKISGFKTSVFK-KKISNILLDGNQLICDESFNEFLTYLIANKVRTFLPFQQ 473

  Fly   409 ELLCEFPERLRGESLRHL-----------NPAMMGCTHADPRKQALIGALL--VGSAATI----- 455
            |::|..||:..|..|:.|           ...::|..... .:.:|:.:.|  :|...|:
 Worm   474 EIMCHGPEKYAGVRLKDLMMKKANETLSEGSRLLGVPQGS-NQHSLLSSFLPSLGPLGTLNGAGG 537

  Fly   456 TALALVLYRCRHKIRETIKG-----GLWGNSALGRKEREYQKTFCDEDYMSRHQHHPCSLGIHST 515
            .|:.||     :.:..||..     |..||..:|...                          |:
 Worm   538 AAIPLV-----NTLTNTIPALRSIPGFGGNIPVGTGA--------------------------SS 571

  Fly   516 FPNT--------YTAPHHPGATHHYGMCP--------------MPVN-------DLGAIDPQQKF 551
            .||.        :|.|....||   |..|              |.||       ||..:||
 Worm   572 VPNKNLNDAIEGFTGPLVRFAT---GGQPVASDIEQLIRSIPNMVVNVPGFGDIDLSKMDP---- 629

  Fly   552 QQLVVPTATMISEKKLNNNKALVSQGAIDDSASFVLHMKSATMGRDVHQQNPQLNHYTKPQFLSA 616
                    ||| :..||..:              :..:..||:.:.|.|...:: |......|:.
 Worm   630 --------TMI-QYVLNGGQ--------------IPGIDKATLDKIVKQTMNKM-HTAAAANLAG 670

  Fly   617 TATVG--------DSCYSYADVPMVHGAPLGGPNQPQLRLTQEHF 653
            ....|        |...|.....::.|.||.|.|:.|.::..|::
 Worm   671 NPVEGQEKVLPPLDKLPSGLVTQVMSGEPLPGLNENQTKIIMEYY 715

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
trn	NP_001261796.1	leucine-rich repeat	62..80	CDD:275380	4/20 (20%)
		LRR	82..406	CDD:443914	90/374 (24%)
		leucine-rich repeat	84..107	CDD:275380	5/22 (23%)
		leucine-rich repeat	108..131	CDD:275380	10/22 (45%)
		leucine-rich repeat	132..155	CDD:275380	8/71 (11%)
		leucine-rich repeat	156..179	CDD:275380	6/22 (27%)
		leucine-rich repeat	180..204	CDD:275380	9/23 (39%)
		leucine-rich repeat	205..228	CDD:275380	6/22 (27%)
		leucine-rich repeat	229..252	CDD:275380	4/22 (18%)
		leucine-rich repeat	253..276	CDD:275380	4/22 (18%)
		leucine-rich repeat	277..300	CDD:275380	8/22 (36%)
		leucine-rich repeat	301..322	CDD:275380	4/20 (20%)
		leucine-rich repeat	326..350	CDD:275380	8/23 (35%)
		leucine-rich repeat	351..373	CDD:275380	4/21 (19%)
		LRRCT	382..434	CDD:214507	14/64 (22%)
egg-6	NP_492348.1	leucine-rich repeat	107..127	CDD:275380	5/21 (24%)
		LRR	128..>457	CDD:443914	82/334 (25%)
		leucine-rich repeat	128..151	CDD:275380	10/22 (45%)
		leucine-rich repeat	152..200	CDD:275380	1/47 (2%)
		leucine-rich repeat	201..224	CDD:275380	7/22 (32%)
		leucine-rich repeat	225..248	CDD:275380	6/22 (27%)
		leucine-rich repeat	249..272	CDD:275380	9/23 (39%)
		leucine-rich repeat	273..294	CDD:275380	6/22 (27%)
		leucine-rich repeat	295..318	CDD:275380	4/22 (18%)
		leucine-rich repeat	319..342	CDD:275380	4/22 (18%)
		leucine-rich repeat	343..366	CDD:275380	8/22 (36%)
		leucine-rich repeat	367..390	CDD:275380	4/23 (17%)
		leucine-rich repeat	391..414	CDD:275380	8/23 (35%)
		leucine-rich repeat	415..434	CDD:275380	3/18 (17%)
		leucine-rich repeat	437..449	CDD:275378	3/11 (27%)