Protein Alignment trn and Gp5

DIOPT Version :10

• Sequence 1: NP_001261796.1
• Gene: trn / 39491
• FlyBaseID: FBgn0010452
• Length: 751
• Species: Drosophila melanogaster
• Sequence 2: NP_032174.2
• Gene: Gp5 / 14729
• MGIID: 1096363
• Length: 567
• Species: Mus musculus
• Alignment Length: 521
• Identity: 126/521 - (24%)
• Similarity: 202/521 - (38%)
• Gaps: 124/521 - (23%)

  Fly     1 MQRNMMIAFVGIWCILASIGVEPAAGLANCPPGCQCDDNTLVV----QCGEGQL-DVLPIALNPS 60
            |.|:.:::     .:||.:..:|..    ||..|:|     ||    ||..|.: .:..:.|..:
Mouse     1 MLRSALLS-----AVLALLRAQPFP----CPKTCKC-----VVRDAAQCSGGSVAHIAELGLPTN 51

  Fly    61 IQRLVIKSNKIKTIDSSI---QFYAELTFLD---LSSNHLMTIPQRTFAYQKKLQEVHLNHNKIG 119
            :..::     :..:|..|   ..::.:|.|.   ||.:|:..|...||....||:.:.|..|||.
Mouse    52 LTHIL-----LFRMDQGILRNHSFSGMTVLQRLMLSDSHISAIDPGTFNDLVKLKTLRLTRNKIS 111

  Fly   120 QISNKTFIGLSAVTVLNLRGNQISELHQGTFTPLLKIEELNLGENRIGYLDPKAFDGLSQLRILY 184
            ::.......:..:..|.|..|.:.:|.|..|..|..::||.|.:|::.:|....|..|.:|::|.
Mouse   112 RLPRAILDKMVLLEQLFLDHNALRDLDQNLFQQLRNLQELGLNQNQLSFLPANLFSSLRELKLLD 176

  Fly   185 LDDNALTTVP-----------------------DPVIFQAMPSLAELFLGMNTLQSIQADAFQDL 226
            |..|.||.:|                       |..:...:.:|.||.|..|.|:|:...||..|
Mouse   177 LSRNNLTHLPKGLLGAQVKLEKLLLYSNQLTSVDSGLLSNLGALTELRLERNHLRSVAPGAFDRL 241

  Fly   227 KGLTRLELKGASLRNISHDSFLGLQELRILDLSDNRLDRIPSVGLSKLVRLEQLSLGQNDFEVIS 291
            ..|:.|.|.|..|.::....||.:..:..|.|.:|.|:.:|.|...::..|.:|.|.......:.
Mouse   242 GNLSSLTLSGNLLESLPPALFLHVSSVSRLTLFENPLEELPDVLFGEMAGLRELWLNGTHLSTLP 306

  Fly   292 EGAFMGLKQLKRLEVNGALRLKRVMTGAFSDNGNLEYLNLSSNKMLLEVQEGALSGLSQLKHVVL 356
            ..||..|..|:.|.:....||..:..|.|.....|..|.|.:| .|.|:::.||.||..|:.|.|
Mouse   307 AAAFRNLSGLQTLGLTRNPRLSALPRGVFQGLRELRVLALHTN-ALAELRDDALRGLGHLRQVSL 370

  Fly   357 KANALTSLAEGLFPWKDLQTLD---------------------------LSENPLSCDCR----V 390
            :.|.|.:|...||  ::|.:|:                           |..||..|||.    :
Mouse   371 RHNRLRALPRTLF--RNLSSLESVQLEHNQLETLPGDVFAALPQLTQVLLGHNPWLCDCGLWPFL 433

  Fly   391 MWLHNLLVAKNASQDDVSELLCEFPERLRGESLRHLNPAMMG------CTHADPRKQALIGALLV 449
            .|                              ||| :|.::|      |...:||.......||.
Mouse   434 QW------------------------------LRH-HPDILGRDEPPQCRGPEPRASLSFWELLQ 467

  Fly   450 G 450
            |
Mouse   468 G 468

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
trn	NP_001261796.1	leucine-rich repeat	62..80	CDD:275380	2/20 (10%)
		LRR	82..406	CDD:443914	98/380 (26%)
		leucine-rich repeat	84..107	CDD:275380	8/25 (32%)
		leucine-rich repeat	108..131	CDD:275380	5/22 (23%)
		leucine-rich repeat	132..155	CDD:275380	7/22 (32%)
		leucine-rich repeat	156..179	CDD:275380	7/22 (32%)
		leucine-rich repeat	180..204	CDD:275380	8/46 (17%)
		leucine-rich repeat	205..228	CDD:275380	10/22 (45%)
		leucine-rich repeat	229..252	CDD:275380	7/22 (32%)
		leucine-rich repeat	253..276	CDD:275380	6/22 (27%)
		leucine-rich repeat	277..300	CDD:275380	6/22 (27%)
		leucine-rich repeat	301..322	CDD:275380	6/20 (30%)
		leucine-rich repeat	326..350	CDD:275380	10/23 (43%)
		leucine-rich repeat	351..373	CDD:275380	8/21 (38%)
		LRRCT	382..434	CDD:214507	11/61 (18%)
Gp5	NP_032174.2	LRR 7	219..240		9/20 (45%)
		leucine-rich repeat	220..243	CDD:275380	10/22 (45%)
		LRR 8	243..264		6/20 (30%)
		leucine-rich repeat	244..267	CDD:275380	7/22 (32%)
		LRR 9	267..288		6/20 (30%)
		leucine-rich repeat	268..291	CDD:275380	6/22 (27%)
		LRR 10	291..312		5/20 (25%)
		leucine-rich repeat	292..315	CDD:275380	6/22 (27%)
		LRR 11	315..337		6/21 (29%)
		leucine-rich repeat	316..338	CDD:275380	6/21 (29%)
		LRR 12	340..361		8/21 (38%)
		leucine-rich repeat	341..364	CDD:275380	10/23 (43%)
		LRR 13	364..385		8/22 (36%)
		leucine-rich repeat	365..388	CDD:275380	9/24 (38%)
		LRR 14	388..409		1/20 (5%)
		leucine-rich repeat	389..410	CDD:275380	1/20 (5%)
		LRRCT	421..>454	CDD:214507	12/63 (19%)
		LRR_8	<65..110	CDD:404697	12/44 (27%)
		LRR 1	75..96		7/20 (35%)
		leucine-rich repeat	76..99	CDD:275380	7/22 (32%)
		LRR	95..424	CDD:443914	86/331 (26%)
		LRR 2	99..120		6/20 (30%)
		leucine-rich repeat	100..123	CDD:275380	5/22 (23%)
		LRR 3	123..144		6/20 (30%)
		leucine-rich repeat	124..147	CDD:275380	7/22 (32%)
		LRR 4	147..168		6/20 (30%)
		leucine-rich repeat	148..171	CDD:275380	7/22 (32%)
		LRR 5	171..193		7/21 (33%)
		leucine-rich repeat	172..195	CDD:275380	7/22 (32%)
		LRR 6	195..216		1/20 (5%)
		leucine-rich repeat	196..219	CDD:275380	1/22 (5%)