Protein Alignment trn and CPN2

DIOPT Version :10

• Sequence 1: NP_001261796.1
• Gene: trn / 39491
• FlyBaseID: FBgn0010452
• Length: 751
• Species: Drosophila melanogaster
• Sequence 2: NP_001073982.3
• Gene: CPN2 / 1370
• HGNCID: 2313
• Length: 545
• Species: Homo sapiens
• Alignment Length: 461
• Identity: 130/461 - (28%)
• Similarity: 199/461 - (43%)
• Gaps: 57/461 - (12%)

  Fly    11 GIWCILASIGV--EPAAGLANCPPGCQCDDNTLVVQ---CGEGQLDVLPIALNPSIQRLVIKSNK 70
            |.|.:..|:.:  .||   ..||.||.|     .||   |.:.:|..:|:.:.|..:.::.....
Human     4 GAWLLWTSLLLLARPA---QPCPMGCDC-----FVQEVFCSDEELATVPLDIPPYTKNIIFVETS 60

  Fly    71 IKTIDSS------------------IQFYAE-------LTFLDLSSNHLMTIPQRTFAYQKKLQE 110
            ..|:::.                  .||..:       |..|:::.:..:.:....|:....|.:
Human    61 FTTLETRAFGSNPNLTKVVFLNTQLCQFRPDAFGGLPRLEDLEVTGSSFLNLSTNIFSNLTSLGK 125

  Fly   111 VHLNHNKIGQISNKTFIGLSAVTVLNLRGNQISELHQGTFTPLLKIEELNLGENRIGYLDPKAFD 175
            :.||.|.:..:....|..|:|:..|:|:|||:..|.:..|.||..::.|||.:|.:..|..:.|.
Human   126 LTLNFNMLEALPEGLFQHLAALESLHLQGNQLQALPRRLFQPLTHLKTLNLAQNLLAQLPEELFH 190

  Fly   176 GLSQLRILYLDDNALTTVPDPVIFQAMPSLAELFLGMNTLQSIQADAFQDLKGLTRLELKGASLR 240
            .|:.|:.|.|.:|||:.:|..| |..:.||.||||..|.:..:....|..|..|.||.|:..::.
Human   191 PLTSLQTLKLSNNALSGLPQGV-FGKLGSLQELFLDSNNISELPPQVFSQLFCLERLWLQRNAIT 254

  Fly   241 NISHDSFLGLQELRILDLSDNRLDRIPSVGLSKLVRLEQLSLGQNDFEVISEGAFMGLKQLK--R 303
            ::....|..|..|..|.|..|.|..:|:...:....|..|||..|..|.::||.|..|..|:  .
Human   255 HLPLSIFASLGNLTFLSLQWNMLRVLPAGLFAHTPCLVGLSLTHNQLETVAEGTFAHLSNLRSLM 319

  Fly   304 LEVNGALRLKRVMTGAFSDNGNLEYLNLSSNKMLLEVQEGALSGLSQLKHVVLKANALTSLAEGL 368
            |..|....|.   .|.|.|...|..|.|.||. |..:.......||:|:.:.|..|.||:|.||:
Human   320 LSYNAITHLP---AGIFRDLEELVKLYLGSNN-LTALHPALFQNLSKLELLSLSKNQLTTLPEGI 380

  Fly   369 FPWK-DLQTLDLSENPLSCDCRVMWLHNLLVAKNASQDDVSELL-----CEFPERLRGESLRHLN 427
            |... :|..|.|..||..|||.:.:|.|.|      |.....||     |..|..|:|:.:..||
Human   381 FDTNYNLFNLALHGNPWQCDCHLAYLFNWL------QQYTDRLLNIQTYCAGPAYLKGQVVPALN 439

  Fly   428 PAMMGC 433
            ...:.|
Human   440 EKQLVC 445

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
trn	NP_001261796.1	leucine-rich repeat	62..80	CDD:275380	1/35 (3%)
		LRR	82..406	CDD:443914	102/333 (31%)
		leucine-rich repeat	84..107	CDD:275380	3/22 (14%)
		leucine-rich repeat	108..131	CDD:275380	6/22 (27%)
		leucine-rich repeat	132..155	CDD:275380	9/22 (41%)
		leucine-rich repeat	156..179	CDD:275380	7/22 (32%)
		leucine-rich repeat	180..204	CDD:275380	9/23 (39%)
		leucine-rich repeat	205..228	CDD:275380	8/22 (36%)
		leucine-rich repeat	229..252	CDD:275380	6/22 (27%)
		leucine-rich repeat	253..276	CDD:275380	6/22 (27%)
		leucine-rich repeat	277..300	CDD:275380	10/22 (45%)
		leucine-rich repeat	301..322	CDD:275380	6/22 (27%)
		leucine-rich repeat	326..350	CDD:275380	7/23 (30%)
		leucine-rich repeat	351..373	CDD:275380	9/22 (41%)
		LRRCT	382..434	CDD:214507	18/57 (32%)
CPN2	NP_001073982.3	LRRNT	21..53	CDD:214470	11/36 (31%)
		leucine-rich repeat	30..53	CDD:275380	6/22 (27%)
		leucine-rich repeat	75..98	CDD:275380	2/22 (9%)
		LRR	95..419	CDD:443914	103/334 (31%)
		LRR 1	98..119		3/20 (15%)
		leucine-rich repeat	99..122	CDD:275380	3/22 (14%)
		LRR 2	122..143		5/20 (25%)
		leucine-rich repeat	123..146	CDD:275380	6/22 (27%)
		LRR 3	146..167		8/20 (40%)
		leucine-rich repeat	147..170	CDD:275380	9/22 (41%)
		LRR 4	170..191		6/20 (30%)
		leucine-rich repeat	171..194	CDD:275380	7/22 (32%)
		LRR 5	194..215		9/21 (43%)
		leucine-rich repeat	195..218	CDD:275380	9/23 (39%)
		LRR 6	218..239		8/20 (40%)
		leucine-rich repeat	219..242	CDD:275380	8/22 (36%)
		LRR 7	242..263		5/20 (25%)
		leucine-rich repeat	243..266	CDD:275380	6/22 (27%)
		LRR 8	266..287		6/20 (30%)
		leucine-rich repeat	267..290	CDD:275380	6/22 (27%)
		LRR 9	290..311		9/20 (45%)
		leucine-rich repeat	291..314	CDD:275380	10/22 (45%)
		LRR 10	314..335		6/23 (26%)
		leucine-rich repeat	315..338	CDD:275380	7/25 (28%)
		LRR 11	338..359		6/21 (29%)
		leucine-rich repeat	339..359	CDD:275380	6/20 (30%)
		LRR 12	362..383		9/20 (45%)
		leucine-rich repeat	363..382	CDD:275380	8/18 (44%)
		leucine-rich repeat	387..399	CDD:275378	5/11 (45%)
		LRRCT	395..446	CDD:214507	18/57 (32%)