DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment trn and si:ch211-170a17.1

DIOPT Version :9

Sequence 1:	NP_001261796.1	Gene:	trn / 39491	FlyBaseID:	FBgn0010452	Length:	751	Species:	Drosophila melanogaster
Sequence 2:	XP_021336930.1	Gene:	si:ch211-170a17.1 / 101884914	ZFINID:	ZDB-LINCRNAG-131127-306	Length:	628	Species:	Danio rerio

Alignment Length:	461	Identity:	112/461 - (24%)
Similarity:	187/461 - (40%)	Gaps:	64/461 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MQRNMMIAFVGIWCILASIGVEPAAGLA----------NCPPGCQCDDNTLVVQCGEGQLDVLPI 55
            :.|.|:...|..|        :|..|||          .||..|:|...:..|.|...:...:|.
Zfish    18 LSRVMLHTAVSCW--------QPLLGLALVAVFVGSTLACPSRCECSAQSRSVICHRKRYTAIPD 74

  Fly    56 ALNPSIQRLVIKSNKIKTID-SSIQFYAELTFLDLSSNHLMTIPQRTFAYQKKLQEVHLNHNKIG 119
            .:....:.|.:..|:|:.:: .....|..:..||||.|.:..:....|.....|..:.|..|:|.
Zfish    75 GVPLETRILDLSKNRIQAVNPDDFAAYPHIEELDLSGNIIAYVEPGAFNSLYSLHSLSLKSNRIK 139

  Fly   120 QISNKTFIGLSAVTVLNLRGNQISELHQGTFTPLLKIEELNLGENRIGYLDPKAFDGLSQLRILY 184
            .:|...|.|||.:|.|::..|::..|....|..|..:..|::|:|.:.|:..:||.||..|..|.
Zfish   140 LLSLGVFTGLSNLTNLDISDNKVVILVDYMFQDLRNLRSLDVGDNELVYISHRAFSGLLSLESLT 204

  Fly   185 LDDNALTTVPDPVIFQAMPSLAELFLGMNTLQSIQADAFQDLKGLTRLELKG-ASLRNISHDSFL 248
            |:...||.||...: ..:.:|..|.:...|:.::...:|:.|..|..||:.. .||.....:|..
Zfish   205 LERCNLTVVPTDAL-SHLHNLVSLHMRYLTISTLHPYSFKKLFHLRHLEIDNWPSLDVFPANSLH 268

  Fly   249 GLQELRILDLSDNRLDRIPSVGLSKLVRLEQLSLGQNDFEVISEGAFMGLKQLKRLEVNGALRLK 313
            || .|..|.:::..|...|...|..|..|..|:|..:....:..|....|.:|:.|.:.|:
Zfish   269 GL-NLTTLSVTNTNLSTFPYQALHHLPYLTHLNLSYSRIRTVEGGLLQNLVRLRELRLAGS---- 328

  Fly   314 RVMTGAFSDNGNLEYLNLSSNKMLLEVQEGALSGLSQLKHVVLKANALTSLAEGLFPWKD-LQTL 377
                                  .|:.::..|..|:..|:.:.:..|.|.:|.:|.|...: ||.|
Zfish   329 ----------------------HLVSIEPYAFQGIRWLRLLNISHNRLDTLEKGAFHAPEALQVL 371

  Fly   378 DLSENPLSCDCRVMWL----HNLLVAKNASQDDVSELLCEFPERLRGESLRHLNPAMMG----CT 434
            .::.|||.||||:|||    |::.......:       |..||..:....:....|::.    ||
Zfish   372 LINNNPLVCDCRLMWLLQRHHSISFGDTQPE-------CSSPEGSQRRQSKEFKEALLSNYVTCT 429

  Fly   435 HADPRK 440
            ....|:
Zfish   430 KPKIRR 435

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
trn	NP_001261796.1	leucine-rich repeat	62..80	CDD:275380	3/18 (17%)
		LRR_8	83..142	CDD:290566	18/58 (31%)
		leucine-rich repeat	84..107	CDD:275380	6/22 (27%)
		leucine-rich repeat	108..131	CDD:275380	8/22 (36%)
		LRR_RI	129..421	CDD:238064	76/297 (26%)
		LRR_8	132..190	CDD:290566	17/57 (30%)
		leucine-rich repeat	132..155	CDD:275380	6/22 (27%)
		leucine-rich repeat	156..179	CDD:275380	8/22 (36%)
		leucine-rich repeat	180..204	CDD:275380	7/23 (30%)
		LRR_8	203..263	CDD:290566	15/60 (25%)
		leucine-rich repeat	205..228	CDD:275380	5/22 (23%)
		leucine-rich repeat	229..252	CDD:275380	8/23 (35%)
		LRR_8	252..308	CDD:290566	13/55 (24%)
		leucine-rich repeat	253..276	CDD:275380	6/22 (27%)
		leucine-rich repeat	277..300	CDD:275380	5/22 (23%)
		leucine-rich repeat	301..322	CDD:275380	3/20 (15%)
		LRR_8	325..384	CDD:290566	13/59 (22%)
		leucine-rich repeat	326..350	CDD:275380	3/23 (13%)
		leucine-rich repeat	351..373	CDD:275380	6/21 (29%)
si:ch211-170a17.1	XP_021336930.1	leucine-rich repeat	80..103	CDD:275380	4/22 (18%)
		PLN00113	<83..>196	CDD:331614	31/112 (28%)
		leucine-rich repeat	104..127	CDD:275380	6/22 (27%)
		leucine-rich repeat	128..151	CDD:275380	8/22 (36%)
		LRR_8	136..186	CDD:316378	16/49 (33%)
		leucine-rich repeat	152..175	CDD:275380	6/22 (27%)
		leucine-rich repeat	176..223	CDD:275380	15/47 (32%)
		LRR_8	207..255	CDD:316378	12/48 (25%)
		leucine-rich repeat	224..247	CDD:275380	5/22 (23%)
		leucine-rich repeat	248..295	CDD:275380	14/47 (30%)
		LRR_8	271..330	CDD:316378	14/84 (17%)
		leucine-rich repeat	296..319	CDD:275380	5/22 (23%)
		LRR_8	319..378	CDD:316378	16/84 (19%)
		leucine-rich repeat	320..343	CDD:275380	6/48 (13%)
		leucine-rich repeat	344..363	CDD:275380	5/18 (28%)
		PCC	348..>430	CDD:188093	24/88 (27%)
		I-set	431..521	CDD:254352	1/5 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24373
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	2.010