DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment trn and LOC101730277

DIOPT Version :9

Sequence 1:	NP_001261796.1	Gene:	trn / 39491	FlyBaseID:	FBgn0010452	Length:	751	Species:	Drosophila melanogaster
Sequence 2:	XP_004917450.2	Gene:	LOC101730277 / 101730277	-ID:	-	Length:	436	Species:	Xenopus tropicalis

Alignment Length:	525	Identity:	131/525 - (24%)
Similarity:	200/525 - (38%)	Gaps:	143/525 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 CPPGCQC---DDNTLVVQCGEGQLDVLPIALNPSIQRLVIKSN--KIKTIDSSIQFYAELTFLD- 88
            ||..|.|   ||    :||.|..|..||..|..|...|.:..|  :|.|.|:    :..:.||:
Frog    10 CPGMCHCSSEDD----IQCDEAGLTNLPPDLPASAVSLDLAGNLLQILTFDA----FRRVPFLEI 66

  Fly    89 --LSSNHLMTIPQRTFAYQKKLQEVHLNHN-KIGQISNKTFIGLSAVTVLNLRGNQISELHQGTF 150
              ||.|.|..:....|.....|:|::|:.| ::..:...||.|||.:..|:|....|.|:|...|
Frog    67 LCLSQNSLTFLYPGAFIALYNLRELNLSKNPRLTYLHAHTFRGLSHLLSLDLSHCNIFEIHPLVF 131

  Fly   151 TPLLKIEELNLGENRIGYLDPKAFDGLSQLRILYLDDNALTTVPDPVIFQAMPSLAELFLGMNTL 215
            :.:|.:|.|::|.|::.|: |:||..|..:..|.|:.|.:..: ....|:...:|.:|.|..|.:
Frog   132 SHVLSLENLDMGFNKMRYI-PQAFRKLQNITRLSLEKNHIEAI-GINSFKYQHALRDLNLRRNRI 194

  Fly   216 QSIQADAFQDLKGLTRLELKGASLRNISHDSFLGLQELRILDLSDNRLDRIPSVGLSKLVRLEQL 280
            ..||.|||..|..|..|.|...|:.:..:..|.||.:|:|:.|..|::..: :...|:|..|::|
Frog   195 WVIQIDAFNQLNKLNVLNLGHNSISHFPNQLFSGLIQLKIMHLEANKIGSV-NCSFSRLTNLKKL 258

  Fly   281 SLGQNDFEVISEGAFMGLKQLKRLEVNGALRLKRVMTGAFSDNGNLEYLNLSSNKMLLEVQEGAL 345
            .|..|....|:..||..||.:
Frog   259 HLNNNQITWITRNAFGSLKHV-------------------------------------------- 279

  Fly   346 SGLSQLKHVVLKANALTSLAEGLF-PWKDLQTLDLSENPLSCDCRVMWLHNLLVAKNASQDDVSE 409
                ||.|  |..|.|||:...|| ....|:.:.||.||.||||.:.|:...||:.:..   :..
Frog   280 ----QLLH--LSKNNLTSMPSHLFSSMPKLRYVFLSFNPWSCDCSMSWIARWLVSYDGM---IQG 335

  Fly   410 LLCEFPERLRGESLRHL---NPAMM---GCTHADPRKQALIGALLVGSAATITALALVLYRCRHK 468
            :.|.:  .|..:|..|:   |..|.   |.|..|                           |
Frog   336 MHCMY--GLAHQSASHVYMQNGIMCLQEGFTEGD---------------------------C--- 368

  Fly   469 IRETIKGGLWGNSALGRKEREYQKTFCDEDYMSRHQHHPCSLGIHSTFPNTYTAPHHPGAT-HHY 532
                               .|....|.:|.:...|:|           .|.:...||...: :|.
Frog   369 -------------------VESSDQFQNEKFDQCHRH-----------INYHFRKHHSSVSLYHM 403

  Fly   533 GMCPM 537
            .|||:
Frog   404 LMCPI 408

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
trn	NP_001261796.1	leucine-rich repeat	62..80	CDD:275380	5/19 (26%)
		LRR_8	83..142	CDD:290566	18/62 (29%)
		leucine-rich repeat	84..107	CDD:275380	7/25 (28%)
		leucine-rich repeat	108..131	CDD:275380	8/23 (35%)
		LRR_RI	129..421	CDD:238064	78/292 (27%)
		LRR_8	132..190	CDD:290566	19/57 (33%)
		leucine-rich repeat	132..155	CDD:275380	6/22 (27%)
		leucine-rich repeat	156..179	CDD:275380	9/22 (41%)
		leucine-rich repeat	180..204	CDD:275380	4/23 (17%)
		LRR_8	203..263	CDD:290566	21/59 (36%)
		leucine-rich repeat	205..228	CDD:275380	10/22 (45%)
		leucine-rich repeat	229..252	CDD:275380	7/22 (32%)
		LRR_8	252..308	CDD:290566	15/55 (27%)
		leucine-rich repeat	253..276	CDD:275380	6/22 (27%)
		leucine-rich repeat	277..300	CDD:275380	8/22 (36%)
		leucine-rich repeat	301..322	CDD:275380	0/20 (0%)
		LRR_8	325..384	CDD:290566	14/59 (24%)
		leucine-rich repeat	326..350	CDD:275380	0/23 (0%)
		leucine-rich repeat	351..373	CDD:275380	9/22 (41%)
LOC101730277	XP_004917450.2	LRRNT	10..37	CDD:396168	12/30 (40%)
		LRR_8	42..97	CDD:404697	15/58 (26%)
		leucine-rich repeat	42..63	CDD:275378	5/24 (21%)
		leucine-rich repeat	64..87	CDD:275380	6/22 (27%)
		leucine-rich repeat	88..136	CDD:275380	15/47 (32%)
		LRR	<122..>293	CDD:227223	58/223 (26%)
		leucine-rich repeat	137..159	CDD:275380	9/22 (41%)
		leucine-rich repeat	160..183	CDD:275380	4/23 (17%)
		leucine-rich repeat	184..207	CDD:275380	10/22 (45%)
		leucine-rich repeat	208..231	CDD:275380	7/22 (32%)
		leucine-rich repeat	232..254	CDD:275380	6/22 (27%)
		leucine-rich repeat	255..278	CDD:275380	8/22 (36%)
		leucine-rich repeat	279..302	CDD:275380	10/72 (14%)
		TPKR_C2	311..>326	CDD:417692	7/14 (50%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D187891at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010