DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment trn and Chadl

DIOPT Version :9

Sequence 1:	NP_001261796.1	Gene:	trn / 39491	FlyBaseID:	FBgn0010452	Length:	751	Species:	Drosophila melanogaster
Sequence 2:	XP_038936217.1	Gene:	Chadl / 100910434	RGDID:	6504353	Length:	747	Species:	Rattus norvegicus

Alignment Length:	421	Identity:	120/421 - (28%)
Similarity:	166/421 - (39%)	Gaps:	81/421 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 ILASIGVEPAAGLA--NCPPGCQCDDNTLVVQCGEGQLDVLPIALNPSIQRLVIKSNKIKTIDSS 77
            :|..:.:.||..:|  .||..|.||::...|.|....|..:|..:....||
  Rat    20 LLLMMFLSPAWNVAAQRCPQTCVCDNSRRHVTCQHQNLTEVPDTIPELTQR-------------- 70

  Fly    78 IQFYAELTFLDLSSNHLMTIPQRTFAYQKKLQEVHLNHNKIGQISNKTFIGLSAVTVLNLRGNQI 142
                     |||..|.|..||...|.....|..:.|.|.::.|::...|.||..:..|||..|::
  Rat    71 ---------LDLQGNMLKVIPPAAFQDLPYLTHLDLQHCQVEQVAEGAFRGLGRLLFLNLASNRL 126

  Fly   143 SELHQGTFTPLLKIEELNLGENRIGYLDPKAFDGLSQLRILYLDDNALTTVPDPVIFQAMPSLAE 207
            |.|.|                        :|.|||..||.|.|:.|.|..: .|..|.|:.|||.
  Rat   127 SSLPQ------------------------EALDGLGSLRRLELERNMLEEL-RPGTFGALGSLAT 166

  Fly   208 LFLGMNTLQSIQADAFQDLKGLTRLELKGASLRNISHDSFLGLQELRILDLSDNRLDRIPSVGLS 272
            |.|..|.|..:.|.|||.|.....|:|...:|..::.::..||..||.|.|..|.|..:|...||
  Rat   167 LNLAHNALVYLPAMAFQGLMRTRWLQLSHNALSVLAPEALAGLPVLRRLSLHHNELQALPGAALS 231

  Fly   273 KLVRLEQLSLGQNDFEVISEGAFMGLKQLKRLEVNGALRLKRVMTGAFSDNGNLEYLNLSSNKML 337
            :...|.:|.||.|......|...:.|..|:.|.:               |:|:|:.|.
  Rat   232 QARSLARLELGHNPLTYTGEEDGLALPGLRELAL---------------DHGSLQALG------- 274

  Fly   338 LEVQEGALSGLSQLKHVVLKANALTSLAEGLFPWKDLQTLDLSENPLSCDCRVMWLHNLLVAKNA 402
                ..|.:...:|..:.|:.|.||:|.....|.: |:.|.|..|||.|.|....|...||....
  Rat   275 ----PRAFAHCPRLHTLDLRGNQLTTLPPLQVPGQ-LRRLRLQGNPLWCACHARPLLEWLVRARV 334

  Fly   403 SQDDVSELLCEFPERLRGESLRHLNPAMMGC 433
            ..|..    |..|.|||||:|..|.|:.:.|
  Rat   335 RSDGA----CRGPRRLRGETLDTLRPSDLRC 361

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
trn	NP_001261796.1	leucine-rich repeat	62..80	CDD:275380	2/17 (12%)
		LRR_8	83..142	CDD:290566	19/58 (33%)
		leucine-rich repeat	84..107	CDD:275380	8/22 (36%)
		leucine-rich repeat	108..131	CDD:275380	7/22 (32%)
		LRR_RI	129..421	CDD:238064	85/291 (29%)
		LRR_8	132..190	CDD:290566	16/57 (28%)
		leucine-rich repeat	132..155	CDD:275380	7/22 (32%)
		leucine-rich repeat	156..179	CDD:275380	4/22 (18%)
		leucine-rich repeat	180..204	CDD:275380	9/23 (39%)
		LRR_8	203..263	CDD:290566	22/59 (37%)
		leucine-rich repeat	205..228	CDD:275380	11/22 (50%)
		leucine-rich repeat	229..252	CDD:275380	5/22 (23%)
		LRR_8	252..308	CDD:290566	18/55 (33%)
		leucine-rich repeat	253..276	CDD:275380	9/22 (41%)
		leucine-rich repeat	277..300	CDD:275380	7/22 (32%)
		leucine-rich repeat	301..322	CDD:275380	2/20 (10%)
		LRR_8	325..384	CDD:290566	14/58 (24%)
		leucine-rich repeat	326..350	CDD:275380	3/23 (13%)
		leucine-rich repeat	351..373	CDD:275380	7/21 (33%)
Chadl	XP_038936217.1	PLN00113	30..>555	CDD:215061	117/411 (28%)
		leucine-rich repeat	48..66	CDD:275380	4/17 (24%)
		leucine-rich repeat	68..91	CDD:275380	10/45 (22%)
		leucine-rich repeat	92..115	CDD:275380	7/22 (32%)
		leucine-rich repeat	116..139	CDD:275380	11/46 (24%)
		leucine-rich repeat	140..163	CDD:275380	9/23 (39%)
		leucine-rich repeat	164..187	CDD:275380	11/22 (50%)
		leucine-rich repeat	188..211	CDD:275380	5/22 (23%)
		leucine-rich repeat	212..235	CDD:275380	9/22 (41%)
		leucine-rich repeat	236..259	CDD:275380	7/22 (32%)
		leucine-rich repeat	260..283	CDD:275380	7/48 (15%)
		leucine-rich repeat	306..345	CDD:275380	14/42 (33%)
		leucine-rich repeat	425..448	CDD:275380
		PPP1R42	446..603	CDD:411060
		leucine-rich repeat	449..472	CDD:275380
		leucine-rich repeat	473..496	CDD:275380
		leucine-rich repeat	497..520	CDD:275380
		leucine-rich repeat	521..544	CDD:275380
		leucine-rich repeat	545..568	CDD:275380
		leucine-rich repeat	569..592	CDD:275380
		LRR_8	591..653	CDD:404697
		leucine-rich repeat	593..617	CDD:275380
		leucine-rich repeat	618..641	CDD:275380
		leucine-rich repeat	643..665	CDD:275380
		leucine-rich repeat	666..677	CDD:275378
		LRRCT	673..721	CDD:214507
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24373
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.010