Protein Alignment trn and lingo2

DIOPT Version :10

• Sequence 1: NP_001261796.1
• Gene: trn / 39491
• FlyBaseID: FBgn0010452
• Length: 751
• Species: Drosophila melanogaster
• Sequence 2: XP_004910881.1
• Gene: lingo2 / 100490134
• XenbaseID: XB-GENE-922286
• Length: 612
• Species: Xenopus tropicalis
• Alignment Length: 560
• Identity: 144/560 - (25%)
• Similarity: 236/560 - (42%)
• Gaps: 79/560 - (14%)

  Fly    12 IWCILASIGVEPAAGLANCPPGCQCDDNTLVVQCGEGQLDVLPIALNPSIQRLVIKSNKIKTIDS 76
            |.|::|.:.|...:.. .||..|:|......|.|...:|..:|..:....:.|.:..||:|:: :
 Frog    15 ILCLVAMLLVFMGSAF-GCPAKCECSAQNKSVSCHRRRLVTIPEGIPIETKILDLSKNKLKSV-N 77

  Fly    77 SIQF--YAELTFLDLSSNHLMTIPQRTFAYQKKLQEVHLNHNKIGQISNKTFIGLSAVTVLNLRG 139
            .:.|  |..|..:|||.|.:..:....|.....|:.:.|..|::..:....|.|||.:|.|::..
 Frog    78 PVDFVSYPLLEDIDLSDNIISNVEPGAFNSLFNLRSLSLKGNRLKLVPLGVFTGLSNLTKLDISE 142

  Fly   140 NQISELHQGTFTPLLKIEELNLGENRIGYLDPKAFDGLSQLRILYLDDNALTTVPDPVI--FQAM 202
            |:|..|....|..|..::.|.:|:|.:.|:..:||.||..|..|.|:...||.||...:  ...:
 Frog   143 NKIVILLDYMFQDLHSLKSLEVGDNELVYISHRAFSGLVSLEQLTLEKCNLTAVPTDALSHLHNL 207

  Fly   203 PSLAELFLGMNTLQSIQADAFQDLKGLTRLELKGASLRN-ISHDSFLGLQELRILDLSDNRLDRI 266
            .||...:|.:|.|...   ||:.|..|..||:....|.: :..:|..|| .|..|.:::..|..|
 Frog   208 YSLHLKYLNINVLPPF---AFKRLFHLKILEISYWPLLDLVPANSLYGL-NLTFLSITNTNLSTI 268

  Fly   267 PSVGLSKLVRLEQLSLGQNDFEVISEGAFMGLKQLKRLEVNGALRLKRVMTGAFSDNGNLEYLNL 331
            |...|..|:.|..|:|..|...:|..|.|..|.:|:.|.:.|| :|:.:...||.....|..||:
 Frog   269 PYHALKHLIYLTHLNLSYNPIGIIDTGVFSDLVRLQELHLVGA-QLRTIEPHAFQGLRFLRLLNV 332

  Fly   332 SSNKMLLEVQEGALSGLSQLKHVVLKANALTSLAEGLFPWKDLQTLDLSENPLSCDCRVMWL--- 393
            |.|  |||               .|:.||..|      | |.|:.|.:.:|||.||||::|:
 Frog   333 SQN--LLE---------------TLEENAFQS------P-KALEVLCIDDNPLVCDCRLIWMLQR 373

  Fly   394 HNLLVAKNASQDDVSELLCEFPERLRGESLRHLNPAMMG----C------------THADPRKQA 442
            |.:|      .....:.:|..|:.|:..|.:.|:.|::.    |            .|.|..::.
 Frog   374 HPML------HFGGQQPMCSSPDSLKESSYKVLDAAVLSFYFTCKKPKIRDREMLQVHVDEGQRV 432

  Fly   443 LIGALLVGSAATITALALVLYRCRH-KIRETIKGGLWGNSALGRKEREYQKT---FCDEDYMSRH 503
            .:.....|....:  ::.|..|.|. .::...:..:.||..|..:..:.|.|   .|.....:.:
 Frog   433 QMNCNADGDPQPM--ISWVTPRRRTVSLKSNGRTTVLGNGTLEIRYAQIQDTGTYICVASNAAGN 495

  Fly   504 QHHPCSLGIHSTFPN-TYTAPHHPGATHHYGMCPMPVNDL 542
            .....||.:....|: :||           .|.||.:.:|
 Frog   496 DTFSASLTVKGFVPDRSYT-----------NMTPMFITEL 524

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
trn	NP_001261796.1	leucine-rich repeat	62..80	CDD:275380	4/17 (24%)
		LRR	82..406	CDD:443914	98/329 (30%)
		leucine-rich repeat	84..107	CDD:275380	6/22 (27%)
		leucine-rich repeat	108..131	CDD:275380	6/22 (27%)
		leucine-rich repeat	132..155	CDD:275380	7/22 (32%)
		leucine-rich repeat	156..179	CDD:275380	8/22 (36%)
		leucine-rich repeat	180..204	CDD:275380	7/25 (28%)
		leucine-rich repeat	205..228	CDD:275380	7/22 (32%)
		leucine-rich repeat	229..252	CDD:275380	7/23 (30%)
		leucine-rich repeat	253..276	CDD:275380	7/22 (32%)
		leucine-rich repeat	277..300	CDD:275380	8/22 (36%)
		leucine-rich repeat	301..322	CDD:275380	7/20 (35%)
		leucine-rich repeat	326..350	CDD:275380	8/23 (35%)
		leucine-rich repeat	351..373	CDD:275380	5/21 (24%)
		LRRCT	382..434	CDD:214507	17/70 (24%)
lingo2	XP_004910881.1	LRRNT	31..64	CDD:214470	8/32 (25%)
		leucine-rich repeat	43..61	CDD:275380	4/17 (24%)
		LRR	52..>343	CDD:443914	89/313 (28%)
		leucine-rich repeat	63..86	CDD:275380	6/23 (26%)
		leucine-rich repeat	87..110	CDD:275380	6/22 (27%)
		leucine-rich repeat	111..134	CDD:275380	6/22 (27%)
		leucine-rich repeat	135..158	CDD:275380	7/22 (32%)
		leucine-rich repeat	159..182	CDD:275380	8/22 (36%)
		leucine-rich repeat	183..206	CDD:275380	7/22 (32%)
		leucine-rich repeat	207..254	CDD:275380	15/50 (30%)
		leucine-rich repeat	255..278	CDD:275380	7/22 (32%)
		leucine-rich repeat	279..302	CDD:275380	8/22 (36%)
		leucine-rich repeat	303..326	CDD:275380	7/23 (30%)
		leucine-rich repeat	327..347	CDD:275380	11/36 (31%)
		LRRCT	359..402	CDD:214507	15/48 (31%)
		Ig	415..504	CDD:472250	14/90 (16%)
		Ig strand B	432..436	CDD:409353	0/3 (0%)
		Ig strand C	445..449	CDD:409353	0/5 (0%)
		Ig strand E	470..474	CDD:409353	1/3 (33%)
		Ig strand F	484..489	CDD:409353	1/4 (25%)
		Ig strand G	497..500	CDD:409353	0/2 (0%)