Protein Alignment trn and lingo4

DIOPT Version :10

• Sequence 1: NP_001261796.1
• Gene: trn / 39491
• FlyBaseID: FBgn0010452
• Length: 751
• Species: Drosophila melanogaster
• Sequence 2: XP_017945786.1
• Gene: lingo4 / 100489549
• XenbaseID: XB-GENE-6464195
• Length: 626
• Species: Xenopus tropicalis
• Alignment Length: 476
• Identity: 148/476 - (31%)
• Similarity: 210/476 - (44%)
• Gaps: 76/476 - (15%)

  Fly    12 IWCILASIGVEPAAGLANCPPGCQC---------DDNTLVVQCGEGQLDVLPIALNPSIQRLVIK 67
            |.|    :||...|..:.||..|:|         |::||   |....|.::|..|....|.|.:.
 Frog    20 IMC----VGVLMRALCSCCPTPCECPSPCECPARDNSTL---CRRRFLSIVPSDLPTFSQILDLS 77

  Fly    68 SNKIKTIDSSIQFYAELTF---LDLSSNHLMTIPQRTFAYQKKLQEVHLNHNKIGQISNKTFIGL 129
            .|.|:.:.|:.  :..|.:   ||||.|.|..:....|:....|:.:.|:||::..:....|:|:
 Frog    78 HNYIRAVPSNA--FTHLKYLQELDLSYNQLSRVEPGLFSSLPALRVLLLHHNELKLLPPGIFLGM 140

  Fly   130 SAVTVLNLRGNQISELHQGTFTPLLKIEELNLGENRIGYLDPKAFDGLSQLRILYLDDNALTTVP 194
            .|::.|::|.||:..|...||..|.:::.|..|||.:.::.|.||..|.||:.|.|:|..|..||
 Frog   141 PALSWLDVRRNQLVILLDQTFQGLRELKHLETGENPLLFVSPGAFLTLPQLQRLGLEDTKLNGVP 205

  Fly   195 DPVIFQAMPSLAELFLGMNTLQSIQADAFQDLKGLTRLELKG-ASLRNISHDSFLGLQELRILDL 258
            ...: .|:|.|:||.||..:...::..:|.||..|..|||.. .||..:...|..|| .|....:
 Frog   206 SSAL-AALPRLSELRLGGISSSVLRDLSFPDLPLLRVLELDSWPSLGLLEPHSLSGL-NLSSFSV 268

  Fly   259 SDNRLDRIPSVGLSKLVRLEQLSLGQNDFEVISEGAFMGLKQLKRLEVNGALRLKRVMTGAFSDN 323
            :...|..||...|...:.|..|.|..|.   |||....|...|:|||   .|||         .:
 Frog   269 THGNLTTIPEEALKAQIYLRTLDLSYNP---ISELPARGFGTLRRLE---ELRL---------SS 318

  Fly   324 GNLEYLNLSSNKMLLEVQEGALSGLSQLKHVVLKANALTSLAEGLF--PWKDLQTLDLSENPLSC 386
            |.|.|           |..||..||.:|:.:.|..|.||.|||...  |...|:||.||...|||
 Frog   319 GRLHY-----------VPSGAFYGLGRLRTLDLSDNPLTWLAEDALPSPLGGLETLLLSNTMLSC 372

  Fly   387 DCRVMW-LHNLLVAKNASQDDVSELLCEFPERLRG----ESLRHLNPAMMGC-----THADPRKQ 441
            |||:.| ||..|.....|.      :|..|:.|||    :....|.|.:..|     .:..||:
 Frog   373 DCRLCWLLHRRLRFGGKSP------VCAAPDSLRGMVIPDDPEKLCPDLFTCQPPRIVNPGPRE- 430

  Fly   442 ALIGALLV--GSAATITALAL 460
                 |.|  |...||:..:|
 Frog   431 -----LTVREGDVLTISCHSL 446

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
trn	NP_001261796.1	leucine-rich repeat	62..80	CDD:275380	5/17 (29%)
		LRR	82..406	CDD:443914	111/330 (34%)
		leucine-rich repeat	84..107	CDD:275380	8/25 (32%)
		leucine-rich repeat	108..131	CDD:275380	6/22 (27%)
		leucine-rich repeat	132..155	CDD:275380	8/22 (36%)
		leucine-rich repeat	156..179	CDD:275380	8/22 (36%)
		leucine-rich repeat	180..204	CDD:275380	8/23 (35%)
		leucine-rich repeat	205..228	CDD:275380	8/22 (36%)
		leucine-rich repeat	229..252	CDD:275380	9/23 (39%)
		leucine-rich repeat	253..276	CDD:275380	5/22 (23%)
		leucine-rich repeat	277..300	CDD:275380	8/22 (36%)
		leucine-rich repeat	301..322	CDD:275380	7/20 (35%)
		leucine-rich repeat	326..350	CDD:275380	7/23 (30%)
		leucine-rich repeat	351..373	CDD:275380	9/23 (39%)
		LRRCT	382..434	CDD:214507	19/61 (31%)
lingo4	XP_017945786.1	LRR	<72..384	CDD:443914	114/341 (33%)
		leucine-rich repeat	72..94	CDD:275380	6/23 (26%)
		leucine-rich repeat	95..118	CDD:275380	7/22 (32%)
		leucine-rich repeat	119..142	CDD:275380	6/22 (27%)
		leucine-rich repeat	143..166	CDD:275380	8/22 (36%)
		leucine-rich repeat	167..190	CDD:275380	8/22 (36%)
		leucine-rich repeat	191..214	CDD:275380	8/23 (35%)
		leucine-rich repeat	216..238	CDD:275378	7/21 (33%)
		leucine-rich repeat	287..310	CDD:275380	9/25 (36%)
		leucine-rich repeat	311..334	CDD:275380	13/45 (29%)
		leucine-rich repeat	335..353	CDD:275380	8/17 (47%)
		Ig_3	420..532	CDD:464046	8/33 (24%)