DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment trn and XB5838993

DIOPT Version :9

Sequence 1:	NP_001261796.1	Gene:	trn / 39491	FlyBaseID:	FBgn0010452	Length:	751	Species:	Drosophila melanogaster
Sequence 2:	XP_002934278.1	Gene:	XB5838993 / 100488097	XenbaseID:	XB-GENE-5838994	Length:	660	Species:	Xenopus tropicalis

Alignment Length:	572	Identity:	141/572 - (24%)
Similarity:	231/572 - (40%)	Gaps:	126/572 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 MMIAFVGIWCILASIGVEPAAGLANCPPGCQCDDNTLVVQCGEGQLDVLPIALNPSIQRLVIKSN 69
            :::||..:      :...||.  ..||..|.|......|.||...|..:|..:..:...|.:::|
Frog    41 LLLAFDNL------VSTIPAT--TQCPENCTCLPLQQHVLCGNASLTSVPSNVPNNTVELHLQNN 97

  Fly    70 KIKTI-DSSIQFYAELTFLDLSSNHLMTIPQRTFAYQKKLQEVHLNHNKIGQISNKTFIGLSAVT 133
            ....: ||.:|...||..|.||:..:.||....|.....::.:||:.|.:|.:...||..||::.
Frog    98 LFSELHDSFLQDLPELRGLYLSNCEIDTIKPEAFQKVTSIKYLHLDRNHLGDLQEGTFRNLSSLI 162

  Fly   134 VLNLRGNQISELHQGTFTPLLKIEELNLGENRIGYLDPKAFDGLSQLRILYLDDNALTTVPDPVI 198
            .|:|..|||:.:.:|.|.||.|:..|.|..|.:..|...:.:||:|||  :||
Frog   163 YLHLESNQITSIREGLFAPLEKLSALYLSNNLLQELTDGSLNGLTQLR--WLD------------ 213

  Fly   199 FQAMPSLAELFLGMNTLQSIQADAFQDLKGLTRLELKGASLRNISHDSFLGLQELRILDLSDNRL 263
                       ||.|.|.                        .||:.||..:..||.|:|..|.|
Frog   214 -----------LGFNMLS------------------------KISNQSFTAIANLRKLNLERNNL 243

  Fly   264 DRIPSVGLSKLVRLEQLSLGQNDFEVISEGAF-MGLKQLKRLEVNGALRLKRVMTGAFSDNGNLE 327
            ..||| .:.:...|:.|.|..|..:.:|..:| ..|:.:..|.:: :|||::|.:..||....|:
Frog   244 TSIPS-AIRRRTGLQMLRLSGNSIKKLSSSSFGRSLRFITELYLD-SLRLEKVTSMTFSKLRMLK 306

  Fly   328 YLNLSSNKMLLEVQEGALSGLSQLKHVVLKANALTSLAEGLFPWKDLQTLDLSENPLSCDCRVMW 392
            .|:||:                         |:|.||:  ::..|....:.|:.||..|||.::.
Frog   307 VLDLSN-------------------------NSLQSLS--VYNVKIFTKIYLTGNPWRCDCSLIG 344

  Fly   393 LHNLLVAKNASQDDVSELLCEFPERLRGESLRHLNPAMMGC--THADPRKQALIGALLVGSAATI 455
            ||..| .:..:.|...:..|:.|:.|:|:||.::|...:.|  |..|....|...:||..|....
Frog   345 LHTRL-QQTKNLDAEQQAHCDAPKALKGQSLINVNLLKLTCPATGEDISVTASTPSLLGSSQFAN 408

  Fly   456 TALALVLYRCR---HKIR---ETIKGGLWGNSALGRKE--------------REYQKTFCDEDYM 500
            |::..|:...:   |..:   :.:.....||:.:..:|              |..:|...|..:
Frog   409 TSIRSVVETMKPTTHAYKTSPQAMSHSTAGNNKIEAEEQDPCLAKHISNVVVRPVEKESLDVSW- 472

  Fly   501 SRH------------QHHPCSLGIHSTFPNTYTAPHHPGATHHYGMCPMPVN 540
            |.|            :....||.|....||......:||::  |.:|.:|.|
Frog   473 SIHGDYKQFEIRYSTEEEKSSLNIIGDLPNIRLYHLNPGSS--YRVCIVPQN 522

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
trn	NP_001261796.1	leucine-rich repeat	62..80	CDD:275380	4/18 (22%)
		LRR_8	83..142	CDD:290566	19/58 (33%)
		leucine-rich repeat	84..107	CDD:275380	7/22 (32%)
		leucine-rich repeat	108..131	CDD:275380	7/22 (32%)
		LRR_RI	129..421	CDD:238064	76/292 (26%)
		LRR_8	132..190	CDD:290566	21/57 (37%)
		leucine-rich repeat	132..155	CDD:275380	9/22 (41%)
		leucine-rich repeat	156..179	CDD:275380	6/22 (27%)
		leucine-rich repeat	180..204	CDD:275380	4/23 (17%)
		LRR_8	203..263	CDD:290566	13/59 (22%)
		leucine-rich repeat	205..228	CDD:275380	4/22 (18%)
		leucine-rich repeat	229..252	CDD:275380	4/22 (18%)
		LRR_8	252..308	CDD:290566	17/56 (30%)
		leucine-rich repeat	253..276	CDD:275380	9/22 (41%)
		leucine-rich repeat	277..300	CDD:275380	7/23 (30%)
		leucine-rich repeat	301..322	CDD:275380	6/20 (30%)
		LRR_8	325..384	CDD:290566	11/58 (19%)
		leucine-rich repeat	326..350	CDD:275380	4/23 (17%)
		leucine-rich repeat	351..373	CDD:275380	4/21 (19%)
XB5838993	XP_002934278.1	LRRNT	57..91	CDD:214470	9/33 (27%)
		LRR_8	91..147	CDD:338972	16/55 (29%)
		leucine-rich repeat	91..112	CDD:275380	5/20 (25%)
		leucine-rich repeat	113..136	CDD:275380	7/22 (32%)
		LRR_8	136..195	CDD:338972	21/58 (36%)
		leucine-rich repeat	137..160	CDD:275380	7/22 (32%)
		LRR	138..437	CDD:227223	96/377 (25%)
		leucine-rich repeat	161..184	CDD:275380	9/22 (41%)
		leucine-rich repeat	185..208	CDD:275380	6/22 (27%)
		leucine-rich repeat	209..232	CDD:275380	12/71 (17%)
		leucine-rich repeat	233..255	CDD:275380	9/22 (41%)
		leucine-rich repeat	256..280	CDD:275380	7/23 (30%)
		leucine-rich repeat	281..304	CDD:275380	7/23 (30%)
		fn3	456..524	CDD:365830	16/70 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910