DRSC/TRiP Functional Genomics Resources

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Protein Alignment trn and tlr3

DIOPT Version :9

Sequence 1:NP_001261796.1 Gene:trn / 39491 FlyBaseID:FBgn0010452 Length:751 Species:Drosophila melanogaster
Sequence 2:XP_002934448.3 Gene:tlr3 / 100486223 XenbaseID:XB-GENE-491049 Length:897 Species:Xenopus tropicalis


Alignment Length:522 Identity:132/522 - (25%)
Similarity:226/522 - (43%) Gaps:96/522 - (18%)


- Green bases have known domain annotations that are detailed below.


  Fly    35 QCDDNTLVVQCGEGQLDVLPIA------LNP-------SIQRLVIK---SNKIKTIDSSIQFYAE 83
            |.|:::.|   ..|.|::|.:.      :||       .::.|.::   |:.:|..|.|.|....
 Frog   286 QIDNDSFV---SLGALEILNLENNDISHVNPKTFNGLSKVRVLNLRKSLSSNLKLDDLSFQSLHN 347

  Fly    84 LTFLDLSSNHLMTIPQRTFAYQKKLQEVHLNHNKIGQ--ISNKTFIGLSAVTV--LNLRGNQISE 144
            :.:|::.:|.:::|.:.||.....|..:.|:.:.:.|  ::|:||:.||...:  |||....:::
 Frog   348 VQYLNMEANKIISITEHTFIGLTSLTNLSLSDSTLQQHTLTNRTFLSLSKSPLYHLNLTKTGLTK 412

  Fly   145 LHQGTFTPLLKIEELNLGENRIGY-LDPKAFDGLSQLRILYLDDN-ALTTVPDPVIFQAMPSLAE 207
            :..|.|..|..::.|::|.|:|.. :.....:||:.:.::||..| .:|...:..||  .|||::
 Frog   413 IENGAFLCLKHLQLLDMGLNQIDQEVSGNELEGLANIEMIYLSYNRRITLTSNSFIF--APSLSK 475

  Fly   208 LFLGMN--TLQSIQADAFQDLKGLTRLELKGASLRNISHDSFLGLQELRILDLSDNRLDRI---- 266
            |:|...  |.:.:....|:.|:.||.|:|...::.||..|.|..|..||||....|.|.|:    
 Frog   476 LYLRKTALTFRDLNPSPFKVLQNLTVLDLSNNNIANIQEDVFESLSNLRILSFEHNNLARLWKEA 540

  Fly   267 ----PSVGLSKLVRLEQLSLGQNDFEVISEGAFMGLKQLKRLEVNGALRLKRVMTGAFSDNGNLE 327
                |.:.|..|..||:|||..|.|:.|...||.||.:||.|:: |...:..:....|.|..:|.
 Frog   541 NPGGPVLFLKGLKNLEKLSLLSNGFDEIPANAFKGLCKLKVLDI-GENNVYILPPSVFDDQHSLT 604

  Fly   328 YLNLSSNKMLLEVQEGALSGLSQLKHVVLKANALTSLAEGLFP--WKDLQTLDLSENPLSCDCR- 389
            .|:|..                         |.:||:.:.||.  :..|:.|::..||..|.|. 
 Frog   605 LLDLHK-------------------------NLITSVEQDLFKNVFSSLKYLNMGGNPYDCTCES 644

  Fly   390 VMWLHNLLVAKNASQDDV-SELLCEFPERLRGESLRHLNPAMMGCTHADPRKQALIGALLVG--S 451
            :.|..:.|...|.|.... |:.:|..|.|..|..:.:.:        :.|.|:.....|.|.  |
 Frog   645 IAWFASWLNTTNTSVPLAHSQYICNTPARYHGNPVDNFD--------SSPCKELAPFRLFVSTFS 701

  Fly   452 AATITALALVLYRCRHKIRETIKGGLWG---------NSALGRKEREYQKTFCDEDYMSRHQHHP 507
            ...:..|:::|.:        .:|  |.         |..||.||.:.:|...|.|....|..:.
 Frog   702 LMLVFILSVLLIQ--------FQG--WRIHFYWTVSINRILGFKEIDPRKRNFDYDAYIIHAQND 756

  Fly   508 CS 509
            .|
 Frog   757 VS 758

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
trnNP_001261796.1 leucine-rich repeat 62..80 CDD:275380 5/20 (25%)
LRR_8 83..142 CDD:290566 16/62 (26%)
leucine-rich repeat 84..107 CDD:275380 5/22 (23%)
leucine-rich repeat 108..131 CDD:275380 7/24 (29%)
LRR_RI 129..421 CDD:238064 87/309 (28%)
LRR_8 132..190 CDD:290566 15/61 (25%)
leucine-rich repeat 132..155 CDD:275380 6/24 (25%)
leucine-rich repeat 156..179 CDD:275380 6/23 (26%)
leucine-rich repeat 180..204 CDD:275380 6/24 (25%)
LRR_8 203..263 CDD:290566 22/61 (36%)
leucine-rich repeat 205..228 CDD:275380 6/24 (25%)
leucine-rich repeat 229..252 CDD:275380 9/22 (41%)
LRR_8 252..308 CDD:290566 25/63 (40%)
leucine-rich repeat 253..276 CDD:275380 10/30 (33%)
leucine-rich repeat 277..300 CDD:275380 12/22 (55%)
leucine-rich repeat 301..322 CDD:275380 5/20 (25%)
LRR_8 325..384 CDD:290566 11/60 (18%)
leucine-rich repeat 326..350 CDD:275380 3/23 (13%)
leucine-rich repeat 351..373 CDD:275380 5/23 (22%)
tlr3XP_002934448.3 PLN00113 26..>507 CDD:215061 57/225 (25%)
leucine-rich repeat 54..74 CDD:275380
leucine-rich repeat 75..98 CDD:275380
leucine-rich repeat 99..122 CDD:275380
leucine-rich repeat 123..146 CDD:275380
leucine-rich repeat 147..170 CDD:275380
leucine-rich repeat 171..196 CDD:275380
leucine-rich repeat 197..230 CDD:275380
leucine-rich repeat 231..273 CDD:275380
leucine-rich repeat 274..297 CDD:275380 3/13 (23%)
leucine-rich repeat 298..319 CDD:275380 4/20 (20%)
leucine-rich repeat 322..347 CDD:275380 6/24 (25%)
leucine-rich repeat 348..371 CDD:275380 5/22 (23%)
leucine-rich repeat 424..448 CDD:275380 6/23 (26%)
PPP1R42 446..637 CDD:411060 62/218 (28%)
leucine-rich repeat 449..472 CDD:275380 6/24 (25%)
leucine-rich repeat 473..498 CDD:275380 6/24 (25%)
leucine-rich repeat 499..522 CDD:275380 9/22 (41%)
leucine-rich repeat 523..554 CDD:275380 10/30 (33%)
leucine-rich repeat 555..578 CDD:275380 12/22 (55%)
leucine-rich repeat 579..602 CDD:275380 6/23 (26%)
leucine-rich repeat 603..623 CDD:275380 8/44 (18%)
PCC 607..>689 CDD:188093 22/114 (19%)
Tlr3_TMD 691..720 CDD:407816 7/38 (18%)
TIR 746..890 CDD:214587 3/13 (23%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR24373
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
22.010

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