Protein Alignment trn and lrrn1l

DIOPT Version :10

• Sequence 1: NP_001261796.1
• Gene: trn / 39491
• FlyBaseID: FBgn0010452
• Length: 751
• Species: Drosophila melanogaster
• Sequence 2: NP_001106456.1
• Gene: lrrn1l / 100127637
• XenbaseID: XB-GENE-492890
• Length: 738
• Species: Xenopus tropicalis
• Alignment Length: 754
• Identity: 189/754 - (25%)
• Similarity: 283/754 - (37%)
• Gaps: 212/754 - (28%)

  Fly    27 LANCPPGCQCD-----------DNTLVVQCGEGQLDVLPIALNPSIQRLVIKSNKIKTIDSSIQF 80
            |..|||.|.|:           .....|.|.:..|..:|..|:..||.|:::||||..:...:|.
 Frog    35 LGVCPPQCVCETRPWFTPQSVYHEAKTVDCNDLLLTHIPENLSTDIQVLLLQSNKISHLTWELQE 99

  Fly    81 YAELTFLDLSSNHLMTIPQRTFAYQKKLQEVHLNHNKIGQISNKTFIGLSAVTVLNLRGNQISEL 145
            .:.||.||||.||..:|                  :.:| :||     ||.:..|.|..||:.||
 Frog   100 LSNLTELDLSQNHFQSI------------------DDLG-VSN-----LSQLITLYLEENQLREL 140

  Fly   146 HQGTFTPLLKIEELNLGENRIGYLDPKAFDGLSQLRILYLDDNALTTVPDPVIFQAMPSLAELFL 210
            ...:...|..:|||.:..|:|.|:.|:||.||.:|..|:|:.|.|..: ||..|:.:|:|..|.:
 Frog   141 PDYSLKDLGSLEELYINHNQISYIGPRAFSGLGRLLRLHLNANRLEII-DPRWFEDLPNLEILMV 204

  Fly   211 GMNTLQSIQADAFQDLKGLTRLELKGASLRNISHDSFLGLQELRILDLSDNRLDRIPSVGLSKLV 275
            |.|.:.::|:..||.|..|..|.|.|..|.:|..::|.||..|..|...||||..:|...|..|.
 Frog   205 GENPVTALQSLNFQPLGRLHSLVLAGMELEHIPENAFQGLDYLESLSFFDNRLTEVPKEALKNLK 269

  Fly   276 RLEQLSLGQNDFEVISEGAFMGLKQLKRLEVNGALRLKRVMTGAFSDNGNLEYLNLSSNKMLLEV 340
            .|:.|.|.:|....|..|.|.|::.|:.|.:|....|:||...||.|...|..|.:.:|..|..:
 Frog   270 LLKFLDLNKNPIPEIRGGDFTGMEHLEELSLNSMEELERVEAEAFQDLPELIKLEMCNNPRLSYL 334

  Fly   341 Q-EGALSGLSQLKHVVLKANALTSLAEGLFPWKDLQTL------DLSENPLSCDCRVMW--LHNL 396
            . |...|.|..||.::|..|.|     .:.|.|..|.|      .|..||:.|||:..|  |..|
 Frog   335 DPEAFSSNLGALKTLLLNNNRL-----AMVPLKIFQALPGLLEISLYSNPIRCDCQNCWKGLSKL 394

  Fly   397 -LVAKNASQDDVSELLCEFPERLRGESLRHLNPAMMGCTHADPRKQALIGALLVGSAATITALAL 460
             |:...|:       ||             :||.::.
 Frog   395 RLIEAQAT-------LC-------------INPPLVS---------------------------- 411

  Fly   461 VLYRCRHKIRETIKGGLWGNSALGRKEREYQKTFCDEDYMSRHQHHPCSLGIHSTFPNTYTAPHH 525
                 .|..:| |:|..|.|..                        |..:..|...|....|.|.
 Frog   412 -----GHLFQE-IQGQAWLNRC------------------------PPLIDTHLIPPQFQIARHQ 446

  Fly   526 P-----GATHH-----YGMCPMPVNDLGAIDPQQKFQQLVVPTATMISEKKLNNNKAL-VSQGAI 579
            |     .|:.|     |.|.|              ..:.|..|...:   |:|...:| ::....
 Frog   447 PVKLSCQASGHPKPEIYWMTP--------------HGERVTGTNGRV---KINAGGSLEITDAVE 494

  Fly   580 DDSASFVLHMKSATMGRDVHQQNPQLNHYTKPQFLS---ATATVGDSCYSYADVPMVHGAPLGGP 641
            :||.|:...|.::. |.|.......:|...:|:.:|   .|..| .|.::..:..|:.|:.: .|
 Frog   495 EDSGSYTCQMWNSD-GTDSKSVFVSINRTQEPEAMSLLMVTKKV-HSNFAVVEWKMLSGSGV-SP 556

  Fly   642 N--------QPQLRLTQEHFKQRELYDQEMGSEILDHN--YIYSNTHYSMPLEQLGRSKTPTPPP 696
            |        ...:|:...|..    |..::..|:.::|  ::..:|.|.
 Frog   557 NVLVPFQWSSATMRIHNPHIS----YTAKVPLEVQEYNLTHLQPSTKYE---------------- 601

  Fly   697 MPPALPLRNGLCATTGRRSFQQKSASQKQQQN--NNTLR 733
                      :|.|.       .|.||..||:  |.|.|
 Frog   602 ----------VCLTV-------SSVSQPSQQSCLNITTR 623

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
trn	NP_001261796.1	leucine-rich repeat	62..80	CDD:275380	6/17 (35%)
		LRR	82..406	CDD:443914	111/333 (33%)
		leucine-rich repeat	84..107	CDD:275380	9/22 (41%)
		leucine-rich repeat	108..131	CDD:275380	4/22 (18%)
		leucine-rich repeat	132..155	CDD:275380	7/22 (32%)
		leucine-rich repeat	156..179	CDD:275380	11/22 (50%)
		leucine-rich repeat	180..204	CDD:275380	8/23 (35%)
		leucine-rich repeat	205..228	CDD:275380	8/22 (36%)
		leucine-rich repeat	229..252	CDD:275380	9/22 (41%)
		leucine-rich repeat	253..276	CDD:275380	9/22 (41%)
		leucine-rich repeat	277..300	CDD:275380	8/22 (36%)
		leucine-rich repeat	301..322	CDD:275380	8/20 (40%)
		leucine-rich repeat	326..350	CDD:275380	7/24 (29%)
		leucine-rich repeat	351..373	CDD:275380	6/21 (29%)
		LRRCT	382..434	CDD:214507	14/54 (26%)
lrrn1l	NP_001106456.1	leucine-rich repeat	60..79	CDD:275380	5/18 (28%)
		LRR	<78..419	CDD:443914	125/424 (29%)
		leucine-rich repeat	80..102	CDD:275380	8/21 (38%)
		leucine-rich repeat	103..126	CDD:275380	13/46 (28%)
		leucine-rich repeat	127..150	CDD:275380	7/22 (32%)
		leucine-rich repeat	151..174	CDD:275380	11/22 (50%)
		leucine-rich repeat	175..198	CDD:275380	8/23 (35%)
		leucine-rich repeat	199..222	CDD:275380	8/22 (36%)
		leucine-rich repeat	223..246	CDD:275380	9/22 (41%)
		leucine-rich repeat	247..294	CDD:275380	17/46 (37%)
		leucine-rich repeat	295..319	CDD:275380	9/23 (39%)
		leucine-rich repeat	320..345	CDD:275380	7/24 (29%)
		leucine-rich repeat	346..367	CDD:275380	8/25 (32%)
		leucine-rich repeat	370..382	CDD:275378	3/11 (27%)
		IG_like	437..519	CDD:214653	20/99 (20%)
		Ig strand B	448..452	CDD:409353	0/3 (0%)
		Ig strand C	461..465	CDD:409353	1/3 (33%)
		Ig strand E	485..489	CDD:409353	1/3 (33%)
		Ig strand F	499..504	CDD:409353	1/4 (25%)
		Ig strand G	512..515	CDD:409353	0/2 (0%)