Protein Alignment trn and lrrtm4l1

DIOPT Version :9

• Sequence 1: NP_001261796.1
• Gene: trn / 39491
• FlyBaseID: FBgn0010452
• Length: 751
• Species: Drosophila melanogaster
• Sequence 2: NP_001373591.1
• Gene: lrrtm4l1 / 100000724
• ZFINID: ZDB-GENE-080327-15
• Length: 571
• Species: Danio rerio
• Alignment Length: 711
• Identity: 158/711 - (22%)
• Similarity: 259/711 - (36%)
• Gaps: 226/711 - (31%)

  Fly     4 NMMIAFVGIWCILASIGVEPAAGLANCPPGCQCDDNTLVVQCGEGQLDVLPIALNPSIQRLVIKS 68
            :|.:|  |:..:.||..:..::|...||..|.|:..  :|.|.......:|..::.|.|.|.::.
Zfish     7 DMRLA--GLLLLQASSLLLFSSGERMCPYSCHCEGK--IVHCESSAFQDVPENISVSCQGLSLRY 67

  Fly    69 NKIKTIDSSIQFYAELTFLDLSSNHLMTIPQRTFAYQKKLQEVHLNHNKIGQISNKTFIGLSAVT 133
            |.:.|:                      :|.: ||:..:|..::|:||:|..:.::.|.|:..:.
Zfish    68 NDLHTM----------------------LPYQ-FAHLNQLLWLYLDHNQIMFVDSRAFQGVRRLK 109

  Fly   134 VLNLRGNQISELHQGTFTPLLKIEELNLGENRIGYLDPKAFDGLSQLRILYLDDNALTTVPDPVI 198
            .|.|..|:||:||..||..:..:..|:|..|::..|.|..|.||.:|:.|:|..|.||.:|
Zfish   110 ELILSSNRISQLHNVTFHGVPNLRSLDLSYNKLQELQPGQFYGLRKLQNLHLRSNGLTAIP---- 170

  Fly   199 FQAMPSLAELFLGMNTLQSIQADAFQDLKGLTRLELKGASLRNISHDSFLGLQELRILDLSDNRL 263
                                 ..||.:.:.|..|:|....||.::..:||||..|..|.|..|:.
Zfish   171 ---------------------VRAFLECRSLEFLDLGYNRLRVLTRTAFLGLSRLMELHLEHNQF 214

  Fly   264 DRIPSVGLSKLVRLEQLSLGQNDFEVISEGAFMGLKQLKRLEVNGALRLKRVMTGAFSDNGNLEY 328
            .||......:|..|..|.|..|....:::|.......|:||:::|. .::.:....|....||:.
Zfish   215 SRINFFLFPRLANLRALYLQWNRIRAVNQGLPWSWYTLQRLDISGN-EIQVLDPVVFQCLPNLQV 278

  Fly   329 LNLSSNKMLLEVQEGALSGLSQLKHVVLKANALTSLAEGLFPWKDLQTLDLSENPLSCD---C-R 389
            |||.|||         |:.:||               |.:..|..|.|:.|:.|...|.   | .
Zfish   279 LNLESNK---------LANVSQ---------------EVVAAWISLTTISLAGNMWDCGPGICPL 319

  Fly   390 VMWLHNLLVAKNASQDDVSELLCEFPERLRGESLRHLNPAMMGCTHADPRKQALIGALLVGSAAT 454
            |:||.|....|:      :.::|..|:.|:||.:...:...:.|...:
Zfish   320 VVWLKNFRGTKD------TNIICSSPKHLQGEKVIEASKNYIDCDDYE----------------- 361

  Fly   455 ITALALVLYRCRHKIRETIKGGLWGNSALGRKEREYQKTFCDEDY-MSRHQHHPC---------- 508
            |||                      .|.|      |.:|| |.:| ::.....|.
Zfish   362 ITA----------------------QSPL------YLQTF-DPNYDLALEPTEPTMAPTTPPPPL 397

  Fly   509 -SLGIHSTFPNTYTAPHH----PGATHHYGMCPMPVNDLGAIDPQQKFQQ--------LVVPTAT 560
             |....:.||.....|.|    |..|:              .||:...|:        ||.|..
Zfish   398 PSPASEAPFPPPQPRPPHRPTFPSRTN--------------TDPRDSHQRTPSSFDSSLVTPVP- 447

  Fly   561 MISEKKLNNNKALVSQGAIDDSASFVLH---------------MKSATMGRDVHQ--QNP----- 603
              .:..::.:|.::...|:..|.|.||.               ::.:::||...:  |.|
Zfish   448 --EQDNVSFHKVVMGGVALFFSVSLVLSVIYVSCKRYPGATRLLQQSSVGRKRRKKSQEPEQNLS 510

  Fly   604 -QLNHY-------TKPQFL--------SATATVGDS--C---YS---------YADVPMVH 634
             ||..|       ..|:.|        :.|.|:..|  |   ||         ..|:|.:|
Zfish   511 SQLQEYYMSYNPAATPEALEVLGNGTGTCTCTISGSRECENEYSCPRPLPGAWIGDIPTIH 571

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
trn	NP_001261796.1	leucine-rich repeat	62..80	CDD:275380	4/17 (24%)
		LRR_8	83..142	CDD:290566	13/58 (22%)
		leucine-rich repeat	84..107	CDD:275380	3/22 (14%)
		leucine-rich repeat	108..131	CDD:275380	7/22 (32%)
		LRR_RI	129..421	CDD:238064	79/295 (27%)
		LRR_8	132..190	CDD:290566	21/57 (37%)
		leucine-rich repeat	132..155	CDD:275380	9/22 (41%)
		leucine-rich repeat	156..179	CDD:275380	8/22 (36%)
		leucine-rich repeat	180..204	CDD:275380	7/23 (30%)
		LRR_8	203..263	CDD:290566	15/59 (25%)
		leucine-rich repeat	205..228	CDD:275380	2/22 (9%)
		leucine-rich repeat	229..252	CDD:275380	9/22 (41%)
		LRR_8	252..308	CDD:290566	15/55 (27%)
		leucine-rich repeat	253..276	CDD:275380	7/22 (32%)
		leucine-rich repeat	277..300	CDD:275380	5/22 (23%)
		leucine-rich repeat	301..322	CDD:275380	5/20 (25%)
		LRR_8	325..384	CDD:290566	17/58 (29%)
		leucine-rich repeat	326..350	CDD:275380	8/23 (35%)
		leucine-rich repeat	351..373	CDD:275380	2/21 (10%)
lrrtm4l1	NP_001373591.1	leucine-rich repeat	60..83	CDD:275380	7/45 (16%)
		LRR_8	63..118	CDD:404697	16/77 (21%)
		leucine-rich repeat	84..107	CDD:275380	7/22 (32%)
		LRR_8	106..166	CDD:404697	21/59 (36%)
		leucine-rich repeat	108..131	CDD:275380	9/22 (41%)
		leucine-rich repeat	132..155	CDD:275380	8/22 (36%)
		PPP1R42	153..308	CDD:411060	52/204 (25%)
		leucine-rich repeat	156..179	CDD:275380	9/47 (19%)
		leucine-rich repeat	180..203	CDD:275380	9/22 (41%)
		leucine-rich repeat	204..227	CDD:275380	7/22 (32%)
		leucine-rich repeat	228..251	CDD:275380	5/22 (23%)
		leucine-rich repeat	252..275	CDD:275380	5/23 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24373
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	2.010