DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Syx13 and syx-7

DIOPT Version :9

Sequence 1:	NP_001261794.1	Gene:	Syx13 / 39485	FlyBaseID:	FBgn0036341	Length:	284	Species:	Drosophila melanogaster
Sequence 2:	NP_492422.2	Gene:	syx-7 / 172718	WormBaseID:	WBGene00009478	Length:	248	Species:	Caenorhabditis elegans

Alignment Length:	247	Identity:	70/247 - (28%)
Similarity:	117/247 - (47%)	Gaps:	27/247 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    48 MSLSEDIGH--------NITAIHSSTKQLEKQLKLIGTSKEQPNLREKVHTINTKC-NAR--VQT 101
            |..:.|.|:        ||..::....|||..:..:..|.|. ..||: ...|.|. ||:  .:.
Worm     1 MDFNRDAGNETASQLQLNIQNLNQQVIQLESFITNLSDSSES-GQRER-ELFNRKAHNAQELSKE 63

  Fly   102 TSQDLQRLQAVVRHGDRQQKLQLEKLTREFHGVVEKYSNLQRRISS-------AMRQTLQQAQQF 159
            |:..|:|| .|:.:.|:..:...|:|..|:.||:.:....||:.:.       |.....|.|:..
Worm    64 TNALLKRL-VVMSNSDKNLRGVRERLQNEYIGVLNRLQASQRKAAQTEKAGMVAAEMDAQAARDA 127

  Fly   160 AD-QVVETNARA-ELLQQQRLEQAHLQQEHDMLDDRRRQVEQIESDIIDVNQIMTQLSGLVHDQG 222
            |: .:...|.|: ..:|....:|.:||.    :.:|:..::|:|.||.|||.|..:|:.:||:||
Worm   128 AEYDMYGNNGRSGGQMQMTAQQQGNLQD----MKERQNALQQLERDIGDVNAIFAELANIVHEQG 188

  Fly   223 QQMDFIENSIEQTAANVEDGTSELAKAARSRQSYRRKILILLVIAVIIGLIV 274
            ..:|.||.::|.....||.|...:.:|....|..|:|.|:||...||:..|:
Worm   189 DMVDSIEANVEHAQIYVEQGAQNVQQAVYYNQKARQKKLLLLCFFVILIFII 240

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Syx13	NP_001261794.1	Syntaxin_2	54..153	CDD:291208	28/116 (24%)
Syx13	NP_001261794.1	SNARE_syntaxin7_like	190..249	CDD:277200	21/58 (36%)
syx-7	NP_492422.2	SynN	3..111	CDD:214699	28/110 (25%)
syx-7	NP_492422.2	SNARE_syntaxin7_like	156..215	CDD:277200	21/58 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5325
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53539
OrthoDB	1	1.010	-	-		D1204812at2759
OrthoFinder	1	1.000	-	-		FOG0000747
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.830