DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RpS4 and RPS4X

DIOPT Version :9

Sequence 1:	NP_001287055.1	Gene:	RpS4 / 39484	FlyBaseID:	FBgn0011284	Length:	261	Species:	Drosophila melanogaster
Sequence 2:	NP_000998.1	Gene:	RPS4X / 6191	HGNCID:	10424	Length:	263	Species:	Homo sapiens

Alignment Length:	259	Identity:	197/259 - (76%)
Similarity:	233/259 - (89%)	Gaps:	0/259 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MARGPKKHLKRLAAPKAWMLDKLGGVFAPRPSTGPHKLRESLPLLIFLRNRLKYALNGAEVTKIV 65
            |||||||||||:||||.||||||.||||||||||||||||.|||:|||||||||||.|.||.||.
Human     1 MARGPKKHLKRVAAPKHWMLDKLTGVFAPRPSTGPHKLRECLPLIIFLRNRLKYALTGDEVKKIC 65

  Fly    66 MQRLVKVDGKVRTDPTYPAGYMDVITLEKTGEFFRLVYDVKGRFVIHRISAEEAKYKLCKVKKTQ 130
            |||.:|:|||||||.|||||:||||:::||||.|||:||.||||.:|||:.||||||||||:|..
Human    66 MQRFIKIDGKVRTDITYPAGFMDVISIDKTGENFRLIYDTKGRFAVHRITPEEAKYKLCKVRKIF 130

  Fly   131 LGAKGVPFLVTHDGRTIRYPDPLIHANDSVQVDIASGKITDYIKFDSGNLCMITGGRNLGRVGTV 195
            :|.||:|.|||||.||||||||||..||::|:|:.:|||||:||||:|||||:|||.||||:|.:
Human   131 VGTKGIPHLVTHDARTIRYPDPLIKVNDTIQIDLETGKITDFIKFDTGNLCMVTGGANLGRIGVI 195

  Fly   196 VNRERHPGSFDIVHIKDSQGHVFATRLTNVFIIGKGNKPYISLPKGKGVKLSIAEERDKRLAAK 259
            .||||||||||:||:||:.|:.|||||:|:|:|||||||:||||:|||::|:||||||||||||
Human   196 TNRERHPGSFDVVHVKDANGNSFATRLSNIFVIGKGNKPWISLPRGKGIRLTIAEERDKRLAAK 259

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RpS4	NP_001287055.1	PLN00036	1..258	CDD:177670	194/256 (76%)
RPS4X	NP_000998.1	PLN00036	1..260	CDD:177670	197/259 (76%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165143156
Domainoid	1	1.000	121	1.000	Domainoid score	I5688
eggNOG	1	0.900	-	-		E1_COG1471
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H90857
Inparanoid	1	1.050	430	1.000	Inparanoid score	I1730
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG62198
OrthoDB	1	1.010	-	-		D1065966at2759
OrthoFinder	1	1.000	-	-		FOG0001491
OrthoInspector	1	1.000	-	-		otm40879
orthoMCL	1	0.900	-	-		OOG6_100732
Panther	1	1.100	-	-	LDO	PTHR11581
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1247
SonicParanoid	1	1.000	-	-		X948
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	16	15.800