DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RpS4 and RPS4Y2

DIOPT Version :9

Sequence 1:	NP_001287055.1	Gene:	RpS4 / 39484	FlyBaseID:	FBgn0011284	Length:	261	Species:	Drosophila melanogaster
Sequence 2:	NP_001034656.1	Gene:	RPS4Y2 / 140032	HGNCID:	18501	Length:	263	Species:	Homo sapiens

Alignment Length:	259	Identity:	188/259 - (72%)
Similarity:	225/259 - (86%)	Gaps:	0/259 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MARGPKKHLKRLAAPKAWMLDKLGGVFAPRPSTGPHKLRESLPLLIFLRNRLKYALNGAEVTKIV 65
            |||||||||||:||||.||||||.||||||||||||||||.|||::||||||||||.|.||.||.
Human     1 MARGPKKHLKRVAAPKHWMLDKLTGVFAPRPSTGPHKLRECLPLIVFLRNRLKYALTGDEVKKIC 65

  Fly    66 MQRLVKVDGKVRTDPTYPAGYMDVITLEKTGEFFRLVYDVKGRFVIHRISAEEAKYKLCKVKKTQ 130
            ||..:|:|||||.|.|||||::|||::|||||.|||||:.||.|.:|||:.||||||||||:|..
Human    66 MQHFLKIDGKVRVDITYPAGFIDVISIEKTGEHFRLVYNTKGCFAVHRITVEEAKYKLCKVRKIT 130

  Fly   131 LGAKGVPFLVTHDGRTIRYPDPLIHANDSVQVDIASGKITDYIKFDSGNLCMITGGRNLGRVGTV 195
            :|.||:|.|||||.||||||||||..||:||:|:.:||||.:||||:||:||:..|.||||||.:
Human   131 VGTKGIPHLVTHDARTIRYPDPLIKVNDTVQIDLGTGKITSFIKFDTGNVCMVIAGANLGRVGVI 195

  Fly   196 VNRERHPGSFDIVHIKDSQGHVFATRLTNVFIIGKGNKPYISLPKGKGVKLSIAEERDKRLAAK 259
            .||||||||.|:||:||:.|:.||||::|:|:||.||||:||||:|||::|:||||||||||||
Human   196 TNRERHPGSCDVVHVKDANGNSFATRISNIFVIGNGNKPWISLPRGKGIRLTIAEERDKRLAAK 259

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RpS4	NP_001287055.1	PLN00036	1..258	CDD:177670	185/256 (72%)
RPS4Y2	NP_001034656.1	PLN00036	1..260	CDD:177670	188/259 (73%)
		RS4NT	3..39	CDD:285333	32/35 (91%)
		Ribosomal_S4e	95..169	CDD:279271	50/73 (68%)
		KOW_RPS4	175..229	CDD:240511	33/53 (62%)
		40S_S4_C	212..259	CDD:292739	32/46 (70%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165143157
Domainoid	1	1.000	121	1.000	Domainoid score	I5688
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	430	1.000	Inparanoid score	I1730
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG62198
OrthoDB	1	1.010	-	-		D1065966at2759
OrthoFinder	1	1.000	-	-		FOG0001491
OrthoInspector	1	1.000	-	-		otm40879
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11581
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X948
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	11	11.010