DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Srrm1 and AT2G29210

DIOPT Version :9

Sequence 1:	NP_648627.1	Gene:	Srrm1 / 39483	FlyBaseID:	FBgn0036340	Length:	954	Species:	Drosophila melanogaster
Sequence 2:	NP_180484.2	Gene:	AT2G29210 / 817470	AraportID:	AT2G29210	Length:	878	Species:	Arabidopsis thaliana

Alignment Length:	1062	Identity:	304/1062 - (28%)
Similarity:	433/1062 - (40%)	Gaps:	309/1062 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 FTGTNQQQDTRFSDKEKKLMKQMKFGDCLNKRVDMSKVKLDVLRPWISKKITDILHIEDDVVVEF 67
            |.||:.:||||||:|:.||||..||...|...||::|||:||::|||:.::|::|.|||:|::.|
plant     6 FRGTSAEQDTRFSNKQAKLMKSQKFAPELENLVDITKVKMDVMKPWIATRVTELLGIEDEVLINF 70

  Fly    68 VYNQLEEEKYPCPKKMQINMTGFLNGRNARQFMGELWALLLSAQESDSGIPAEFI---------- 122
            :|..| :.|....|::||.:|||:. :|..:||.|||.||||||.:.||:|.:|:
plant    71 IYGLL-DGKVVNGKEIQITLTGFME-KNTGKFMKELWTLLLSAQNNPSGVPQQFLDARAAETKKK 133

  Fly   123 QQKKDEILKREE---------------------EQRQRDRSRSRSRSRSQRDSS--------RRD 158
            |::.:||:|:.|                     |....|...||.|....|.:.        |||
plant   134 QEEANEIMKKREGDKKNIEHDILRKIDSGVEHKETNGMDAKPSRDRPEDGRRADEKNGVKERRRD 198

  Fly   159 ----RQRDRSKSKSR-SRSRSMKPANN-----NGSVPSAAREAAANAAAKIRKRG-SSSAARPGS 212
                |:.|.|:|..| |||||:...|:     :|...|.:...:::|:...|||. |:|..|..|
plant   199 LIPPRRGDASRSPLRGSRSRSISKTNSGSKSYSGERKSRSTSQSSDASISPRKRRLSNSRRRSRS 263

  Fly   213 RERRSSRRPRSRS-----RSRSRT----------AGKKTGSVEPAPAKTVNGRHSTD-----KSS 257
            |..|.|..||.|.     |||||:          .|::.   .|||::.   |.|..     :.|
plant   264 RSVRRSLSPRRRRIHSPFRSRSRSPIRRHRRPTHEGRRQ---SPAPSRR---RRSPSPPARRRRS 322

  Fly   258 PVPPASKNKSRSRSHSRSRSP-----RSRSRSPSAKRSRSRSSSRRSR------RRGRSSSISLS 311
            |.|||.:.:|.|....|.|||     :.||.||.|:|.||...:||.|      ||.||.|   .
plant   323 PSPPARRRRSPSPPARRHRSPTPPARQRRSPSPPARRHRSPPPARRRRSPSPPARRRRSPS---P 384

  Fly   312 PERNQDQFEHRRNKNSVQNKRQYRNNRGDSASSMERGNDRGRQFGGGGGGRRGGRRFSPRGRSPM 376
            |.|      .||:.:.:     ||.||  |.|.:.|.|                     |.|||:
plant   385 PAR------RRRSPSPL-----YRRNR--SPSPLYRRN---------------------RSRSPL 415

  Fly   377 RQDNGGGNGGNRFQRSNSRRRSRSRRLSRSPMRYSRSPRRFNNRRRSPMMNFRGGGRGGGRGGGH 441
            .:                |.||.|...|.||:...|.|.  ..|..||.:..|...
plant   416 AK----------------RGRSDSPGRSPSPVARLRDPT--GARLPSPSIEQRLPS--------- 453

  Fly   442 RQMWQHRGGSPNFRGGGRIHWQARHSPGGGGRGGG-------GGMGRFDRRQSPQQNRYNRDHRQ 499
            ..:.|.....|..|.|......|:..|....|..|       ||....:..:||
plant   454 PPVAQRLPSPPPRRAGLPSPPPAQRLPSPPPRRAGLPSPMRIGGSHAANHLESP----------- 507

  Fly   500 SPMQQNQPFRKQFSPHQGPGRRFSSPQQRRNSRDRRPNSRERRSSPGGGG-----GHMNRWDNPP 559
            ||...:.|.||:..|        |.|.:||  |...|:  |.|.|...||     .|:.:..:..
plant   508 SPSSLSPPGRKKVLP--------SPPVRRR--RSLTPD--EERVSLSQGGRHTSPSHIKQDGSMS 560

  Fly   560 PARNRRSSSGSSAGGRQQ------RQRSASPPEKR-RSSHSRSRSLSRNRSRSRSSSQH-SRKRE 616
            |.|.|..||.||   |.|      |:||.:|..:| |.|.|.|||..|.|.||.|||:. ||.|.
plant   561 PVRGRGKSSPSS---RHQKARSPVRRRSPTPVNRRSRRSSSASRSPDRRRRRSPSSSRSPSRSRS 622

  Fly   617 SPIGRSSVEYAGPAVNTIDLCREEQQRKNKPETIIVLDEGPAVRSSYASLSRTPSPFLKPHERLA 681
            .|:...|....|         |:.|:.:..|..:  .:|...|::| ..|.||..|.....::|
plant   623 PPVLHRSPSPRG---------RKHQRERRSPGRL--SEEQDRVQNS-KLLKRTSVPDTDKRKQL- 674

  Fly   682 AAKAAAAASAAVPKKSRD-------QSQSSSSDSSAESDDSEEQPRRKKQPTNMETSKGKKEKVR 739
                        |:|..:       :.|...||..:|..........:..|  :|.|:|:...|
plant   675 ------------PEKLLEVGRVEHYKEQERKSDKLSEKRSVHRHHGSQMSP--VENSEGRSRPV- 724

  Fly   740 RSSESSTSSEQSDDEDNSSGDERLKKKLQQRKSKEAAALKGKEKEHEKEKDK-RRSDKKSKRGAI 803
              |.....|||.:.||||..|..|             :...|:....:.||| ||.:|:|.|..:
plant   725 --SSKVKDSEQVEKEDNSDLDANL-------------SCDSKDTIRHQIKDKNRRKNKRSSREEV 774

  Fly   804 SSGDEESTSSRKRGHKKTRRDEAGDNSDSEDEHVPKKKRKKAKKPADSSDSDSEASSKRKKHKKH 868
            ||.|..|:                 :||.:|....|::||:.||       ..:...||::.::|
plant   775 SSDDNGSS-----------------DSDVDDRKEAKRRRKEEKK-------TRKEEKKRRREERH 815

  Fly   869 KKHSKKSKKHKKHKRK----CSAGKSRADSSSQGSSDEDEQLPHSVAAKRNGNAGKLALLLPGAS 929
            :|..::....:|||::    .|.|:..|....:...:.|        .||
plant   816 RKREERRGGKEKHKKQELSDTSEGEVEARPKIKKGEESD--------PKR--------------- 857

  Fly   930 GAGVINEDLEKQLRERALKSMK 951
                    ||.:||.:||:|:|
plant   858 --------LEIELRNKALESLK 871

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Srrm1	NP_648627.1	PWI	43..113	CDD:279781	33/69 (48%)
AT2G29210	NP_180484.2	PWI	46..114	CDD:279781	33/69 (48%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	69	1.000	Domainoid score	I3462
eggNOG	1	0.900	-	-		E1_KOG2146
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	240	1.000	Inparanoid score	I1085
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0005511
OrthoInspector	1	1.000	-	-		oto3216
orthoMCL	1	0.900	-	-		OOG6_103077
Panther	1	1.100	-	-	LDO	PTHR23148
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	8.950