Protein Alignment Srrm1 and Srrm1

DIOPT Version :9

• Sequence 1: NP_648627.1
• Gene: Srrm1 / 39483
• FlyBaseID: FBgn0036340
• Length: 954
• Species: Drosophila melanogaster
• Sequence 2: NP_058079.2
• Gene: Srrm1 / 51796
• MGIID: 1858303
• Length: 923
• Species: Mus musculus
• Alignment Length: 1079
• Identity: 323/1079 - (29%)
• Similarity: 463/1079 - (42%)
• Gaps: 297/1079 - (27%)

  Fly     3 FTGTNQQQDTRFSDKEKKLMKQMKFGDCLNKRVDMSKVKLDVLRPWISKKITDILHIEDDVVVEF 67
            |.||:.:||.|||:|:|||:||:||.:||.|:||||||.|:|::|||:|::|:||..|||||:||
Mouse     6 FRGTSAEQDNRFSNKQKKLLKQLKFAECLEKKVDMSKVNLEVIKPWITKRVTEILGFEDDVVIEF 70

  Fly    68 VYNQLEEEKYPCPKKMQINMTGFLNGRNARQFMGELWALLLSAQESDSGIPAEFIQQKKDEILKR 132
            ::||| |.|.|..|.||||:||||||:|||:||||||.|||||||:.:|||:.|::.||:||.:|
Mouse    71 IFNQL-EVKNPDSKMMQINLTGFLNGKNAREFMGELWPLLLSAQENIAGIPSAFLELKKEEIKQR 134

  Fly   133 EEEQ------RQRDRSRSRSRSRSQRDSSRRDRQRDRSKSKSRSRSRSMKPANNNGSVPSAAREA 191
            :.||      :::|..:.: |.:.:::|||  .:|:||:|..|.:|||..|
Mouse   135 QIEQEKLASLKKQDEDKDK-RDKEEKESSR--EKRERSRSPRRRKSRSPSP-------------- 182

  Fly   192 AANAAAKIRKRGSSSAARPGSRERRSSRRPRSRSRSRSRTAG--KKTGSVE-PAPA-----KTVN 248
                     :|.||...|  .|:|..||.||.|::|||.:..  ||..|.| |.|:     .:|.
Mouse   183 ---------RRRSSPVRR--ERKRSHSRSPRHRTKSRSPSPAPEKKEKSPELPEPSVRMKDSSVQ 236

  Fly   249 GRHSTD------KSSPVP----PA-SKNKSRSRSHSRSRSPRSRSRSPSAKRSRSRSSSR-RSRR 301
            ...||.      |..|||    |: .||..:.:..:|   |||||||.|..|:||||.|. |.||
Mouse   237 EATSTSDILKAPKPEPVPEPKEPSPEKNSKKEKEKTR---PRSRSRSKSRSRTRSRSPSHTRPRR 298

  Fly   302 RGRSSSISLSPERNQDQF------------------EHRRNKNSVQNKRQYRNNRGDSASSMERG 348
            |.||.|.|.||.|.....                  .|||:::  ..:|:.|::...|.||....
Mouse   299 RHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRS--PGRRRRRSSASLSGSSSSSS 361

  Fly   349 NDRGRQFGGGGGGR-----RGGRRFSPRGRSPMRQDNGGGNGGNRFQRSNSRRRSRSRRLSRSP- 407
            :.|.|........|     |..||.||....|                   |||.|....:..|
Mouse   362 SSRSRSPPKKPPKRTSSPPRKTRRLSPSASPP-------------------RRRHRPSSPATPPP 407

  Fly   408 -MRYSRSPRRFNNRRRSPMMNFRGGGRGGGRGGGHRQMWQHRGGSPNFRGGGRIHWQARHSPGGG 471
             .|:|.:|::.|..|:|.:      ....||..|  ::.:|:|            .:.|.||...
Mouse   408 KTRHSPTPQQSNRTRKSRV------SVSPGRTSG--KVTKHKG------------TEKRESPSPA 452

  Fly   472 GR-----------GGGGGMGRFD----RRQSPQQN----------------RYNRDH-------- 497
            .:           ..|..|...|    |||..:||                |..|.|
Mouse   453 PKPRKVELSESEEDKGSKMAAADSVQQRRQYRRQNQQSSSDSGSSSTSEDERPKRSHVKNGEVGR 517

  Fly   498 --RQSPMQQNQPF----RKQFSPHQGPGRRFSSPQQRRNSRDRRPNSRERRSSPGGGGGHMNRWD 556
              |.||.:...|.    :|:.||....|:|:.||..:        :||.|||            .
Mouse   518 RRRHSPSRSASPSPRKRQKETSPRMQMGKRWQSPVTK--------SSRRRRS------------P 562

  Fly   557 NPPPARNRRSSSGS----SAGGRQQRQRSASPPEKRRSSHSRSRSLSRNRSRSRSSSQHSRKRES 617
            :|||||.|||.|.:    ......:|:||.:||.:||:.....|                  |.|
Mouse   563 SPPPARRRRSPSPAPPPPPPPPPPRRRRSPTPPPRRRTPSPPPR------------------RRS 609

  Fly   618 PIGRSSVEYAGPAVNTIDLCREEQQRKNKPETIIVLDEGPAVRSSYAS----LSRTPSPFLKPHE 678
            |..|   .|:.|.           ||:..|        .|..:...||    ..|..||...|..
Mouse   610 PSPR---RYSPPI-----------QRRYSP--------SPPPKRRTASPPPPPKRRASPSPPPKR 652

  Fly   679 RLAAAKAAAAASAAVPKK------SRDQSQSSSSDSSAESDDSEEQPRRKKQPTNMETSKGKKEK 737
            |::.:......|..|.|:      |:.:..||...|:.|:...:...|....|............
Mouse   653 RVSHSPPPKQRSPTVTKRRSPSLSSKHRKGSSPGRSTREARSPQPNKRHSPSPRPRAPQTSSPPP 717

  Fly   738 VRRSSESSTSSEQSDDEDNSSGDERLKKKLQQRKSKEAAALKGKEKEHEKEKDKRRSDKKSKRGA 802
            |||.:.:|....|| ...::....|:.:..:.:|.|:||:       ...:..:|.|..:|
Mouse   718 VRRGASASPQGRQS-PSPSTRPIRRVSRTPEPKKIKKAAS-------PSPQSVRRVSSSRS---- 770

  Fly   803 ISSGDEESTSSRKRGHKKTRRDEAGDNSDSEDEHVPKKKRKKAKKPADS----SDSDSEASSKRK 863
             .||..|..:.:........:.::...:.|     |....||||.|..|    .:||.|...|:|
Mouse   771 -VSGSPEPAAKKPPAPPSPVQSQSPSTNWS-----PAVPAKKAKSPTPSLSPARNSDQEGGGKKK 829

  Fly   864 KHKKHKKH--SKKSKKHKKHKRK--------CSAGKSRADSSSQGSSDED-----EQLPHSVAAK 913
            |.||.|||  .||.|||||||::        .:|..:...:::..|:.|:     |....:.:..
Mouse   830 KKKKDKKHKKDKKHKKHKKHKKEKAVTIATPATAAPAAVSAATTTSAQEEPAAAPEPRKETESEA 894

  Fly   914 RNGNAGKLALLLPGASGAGVINEDLEKQLRERALKSMKK 952
            .:.|.                 :|||:.|||:||:||:|
Mouse   895 EDDNL-----------------DDLERHLREKALRSMRK 916

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Srrm1	NP_648627.1	PWI	43..113	CDD:279781	47/69 (68%)
Srrm1	NP_058079.2	PWI	46..115	CDD:279781	46/68 (68%)
		Hepatitis_core	<626..717	CDD:279277	21/100 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167838117
Domainoid	1	1.000	104	1.000	Domainoid score	I6742
eggNOG	1	0.900	-	-		E1_KOG2146
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	322	1.000	Inparanoid score	I2495
Isobase	1	0.950	-	0	Normalized mean entropy	S3004
OMA	1	1.010	-	-		QHG46603
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0005511
OrthoInspector	1	1.000	-	-		oto93904
orthoMCL	1	0.900	-	-		OOG6_103077
Panther	1	1.100	-	-	LDO	PTHR23148
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1912
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	12	11.870