DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Srrm1 and corn

DIOPT Version :9

Sequence 1:	NP_648627.1	Gene:	Srrm1 / 39483	FlyBaseID:	FBgn0036340	Length:	954	Species:	Drosophila melanogaster
Sequence 2:	NP_729220.2	Gene:	corn / 38786	FlyBaseID:	FBgn0259173	Length:	1107	Species:	Drosophila melanogaster

Alignment Length:	796	Identity:	162/796 - (20%)
Similarity:	264/796 - (33%)	Gaps:	238/796 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   177 PANNNGSVPSAAREAAANAAAKIR-KRGSSS-------------------------AARPGSRER 215
            |.|.:||  .:..:.|:...::|. :||.||                         |..|.....
  Fly    42 PGNCDGS--DSGLDVASCCHSRITLQRGLSSTSGGYTSSNGLEEIYDSCELKVTTVAQTPSETGS 104

  Fly   216 RSSRRPRSRSRSRSRTAGKKTGSVEPAPAKT-----VNGRHSTDKSSPVPPASKNKSRSRSHSRS 275
            ..:..||     |:.:..||....||.|..|     :.||.:            |..|:.|..|:
  Fly   105 EKTSPPR-----RTGSVKKKVAMFEPEPTGTPAKDQLRGRVA------------NLKRAESLPRN 152

  Fly   276 RSPRSRSRSPSAKRSRSR---SSSRRSRRRGRSSSISLSPERNQDQFEHRRNK-NSVQNKRQYRN 336
            .:......:||..|.::|   ||.|.....|..||..|:..:..|...:..|: .|||...|.:.
  Fly   153 SAAPGTPGTPSTHRDKARLSTSSFRVPSTTGTPSSSRLARPQKPDTLPNALNRAQSVQRLTQVQR 217

  Fly   337 NRGDSASSMERG------NDRGRQFGGGGGGRRG--------GRRF----SPRGRSPMR------ 377
                 ..|:.|.      :|.||.....|..|||        ..|.    :|.|..|.|
  Fly   218 -----TPSLSRARTPGTPSDDGRWPANRGAARRGMSVTPEVTTNRMRGSPAPGGTLPRRRKQQSV 277

  Fly   378 QDNGGGNGGNRFQRSNSRRRSR--SRRLSRSPM-----RYSRSP--RRFNNRRR----SPMMNFR 429
            :|..||    |..||||..|:.  ..|::.|.|     |.|.:|  .:.|:.||    :|.....
  Fly   278 EDLTGG----RLSRSNSISRAAIVDARMTSSVMVVPTSRRSLAPAAAKVNSLRRPQPATPRTRIY 338

  Fly   430 GGGRGGGRGGGHRQMWQHRGGSPNFR---GGGRIHWQARHSPGGGGRGGGGGMGRFDRRQSPQQN 491
                       |....|....|.:..   |||.:..:|..:.                .|..|..
  Fly   339 -----------HETAVQTALTSEDLEQVLGGGLLQTRAVDAV----------------EQRNQST 376

  Fly   492 RYNRDHRQSPMQQNQPFRKQFSPHQGPGR--RFSSPQQRRNSRDR----------------RPNS 538
            :...|.|:..::|.:...:|.|......|  :.:..|:...:.:|                .|.|
  Fly   377 QAEPDQREFELEQLRHEVRQLSGKLQREREEKLAMQQELHLNTERVMGMLELARVVSASAGTPTS 441

  Fly   539 RERRSSPGGGGGHMNRWDNPPPARNRRSSSGSSAGGRQQ---RQRS---ASPPEKRRSSHSRSRS 597
            .:    .|.|.||    |:.....::...||.....|||   :.||   |...|.|||..::...
  Fly   442 ED----SGDGSGH----DSLLMLESQIQISGHELFERQQEIGQLRSMCRALQLEMRRSLATQQLL 498

  Fly   598 LSRNRSRSRSSS------QHSRKRESPIGRS-SVEYAGPAVNTI----------DLCR-----EE 640
            |....:..:.||      ||.:..:....|. ..:|....:...          |.||     .|
  Fly   499 LQEKAAIEQESSELQDFLQHEKAAQCDALRDLEADYQAVKLQLANREEEAKVLRDECRHLVRLNE 563

  Fly   641 QQRKNKPETIIVLDEGPAVRSSYASLSRTPSPFLKPHERLAAAKAAAAASAAVPKKSR-----DQ 700
            |:|:          |...:::.:.:|.......:  |::.|:...|:.|.:.:  .||     :|
  Fly   564 QRRQ----------ENRLLQTKFTALENKSRELI--HQQNASVAGASTALSGL--HSRLDGLVEQ 614

  Fly   701 SQSSSSDSSAESDD-----SEEQPRRKKQPTNME------TSKGKKEKVRRSSESSTSSEQSDDE 754
            ...|.|.|..:.:|     ..|..:..::|..::      .|......:..:|:.|.|
  Fly   615 LVYSYSISEQDLEDIRFQAETEHVQNGQRPNGLDLPICPAASGDAIHTLVLASDGSLS------- 672

  Fly   755 DNSSGDERLKKKLQQRKSKEAAALKGKEKEHEKEKDKRRSDKKS-KRGAISSGDEESTSSRKRGH 818
                         .||.....||:.|..::......||.|.::: |:..:..|..::.|:..:|.
  Fly   673 -------------PQRNQSFIAAVIGAIRQATTHSGKRLSLRQAGKKNGVGLGSAQAVSAGTQGQ 724

  Fly   819 KKTRRDEAGDNSDSED 834
            :....   ||:|||.:
  Fly   725 EPQGN---GDDSDSTE 737

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Srrm1	NP_648627.1	PWI	43..113	CDD:279781
corn	NP_729220.2	PHA03247	<92..336	CDD:223021	67/269 (25%)
corn	NP_729220.2	SMC_prok_B	<340..627	CDD:274008	60/324 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S3004
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.950