DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment AdenoK and adka

DIOPT Version :9

Sequence 1:	NP_001287054.1	Gene:	AdenoK / 39479	FlyBaseID:	FBgn0036337	Length:	345	Species:	Drosophila melanogaster
Sequence 2:	NP_997956.1	Gene:	adka / 368220	ZFINID:	ZDB-GENE-030425-3	Length:	359	Species:	Danio rerio

Alignment Length:	341	Identity:	171/341 - (50%)
Similarity:	239/341 - (70%)	Gaps:	2/341 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 LQEGILVGCGNPLLDISAVVPLNFLQKYSMNEDDAILAEDRHMPIYGELVEGYQAEFLAGGSVQN 69
            |.:..|.|.|||||||.|||..:||.||.:..:|.|||||:|..::.|:|:.::.|:.|||:.||
Zfish    18 LSQNALFGMGNPLLDICAVVDKDFLDKYGLKPNDQILAEDKHKEMFEEMVKKFKVEYRAGGATQN 82

  Fly    70 SLRIAQWILRQP-RVAVFFGCVGEDRYANILKEKAQAAGLDVHYQVKKDVPTGTCAVLITGTHRS 133
            |:::|||::::| .|..||||:|:|::..||||||:.|.:|.||..:.:.|||:||..|||.:||
Zfish    83 SVKVAQWMIQEPHNVGTFFGCIGKDKFGKILKEKAEEAHVDAHYYEQSEEPTGSCAACITGDNRS 147

  Fly   134 LCANLAAANNFTID-HLEEPSNKALVDNAQYYYISGFFLTVNPPSIMQVAATAHAKQRPFLMNLS 197
            |.|||||||.:..: ||:...|..||:.||.|||:||||||:..||::||..|....:.|.:|||
Zfish   148 LVANLAAANCYKKEKHLDLEENWKLVEKAQVYYIAGFFLTVSLESILKVAKHASENNKIFCLNLS 212

  Fly   198 APFISQFYMAPLLAALPYVDIIFGNEAEAQAFAEAQQWPSGDLREIGKRLVAMEKKNPTRPRIAI 262
            ||||.:|:...|:..:|||||:||||.||.|||..|.:.:.|:.||.|:..::.|:|..|.||.:
Zfish   213 APFICEFFKEALMKVMPYVDILFGNETEAAAFAREQGFETEDIEEIAKKAQSLPKENKKRQRIVV 277

  Fly   263 LTQGCDPVLLIQQDSVQEFPVTKLAVHEIVDTNGAGDAFVGGFLSQFVQGKSLDVCIRCGNYAAG 327
            .|||.:..::.:.|.|:.|||.::...|||||||||||||||||||.||.|:.:.|||.|:|||.
Zfish   278 FTQGKEGTVMAKGDKVETFPVLEIDQSEIVDTNGAGDAFVGGFLSQLVQDKTFEQCIRAGHYAAN 342

  Fly   328 HIIKNPGCTYSGEPEF 343
            .||::.|||:..:|:|
Zfish   343 VIIRHAGCTFPEKPDF 358

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AdenoK	NP_001287054.1	PTZ00247	10..343	CDD:240328	169/334 (51%)
AdenoK	NP_001287054.1	ribokinase_pfkB_like	14..343	CDD:294126	167/330 (51%)
adka	NP_997956.1	PTZ00247	23..358	CDD:240328	169/334 (51%)
adka	NP_997956.1	ribokinase_pfkB_like	26..358	CDD:294126	167/331 (50%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170581955
Domainoid	1	1.000	309	1.000	Domainoid score	I1308
eggNOG	1	0.900	-	-		E1_COG0524
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H4891
Inparanoid	1	1.050	345	1.000	Inparanoid score	I2301
OMA	1	1.010	-	-		QHG53733
OrthoDB	1	1.010	-	-		D1226324at2759
OrthoFinder	1	1.000	-	-		FOG0003751
OrthoInspector	1	1.000	-	-		otm26440
orthoMCL	1	0.900	-	-		OOG6_100649
Panther	1	1.100	-	-	O	PTHR45769
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R25
SonicParanoid	1	1.000	-	-		X2162
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	16	15.800