DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment AdenoK and adk-1

DIOPT Version :9

Sequence 1:	NP_001287054.1	Gene:	AdenoK / 39479	FlyBaseID:	FBgn0036337	Length:	345	Species:	Drosophila melanogaster
Sequence 2:	NP_502104.1	Gene:	adk-1 / 178028	WormBaseID:	WBGene00011128	Length:	342	Species:	Caenorhabditis elegans

Alignment Length:	334	Identity:	176/334 - (52%)
Similarity:	243/334 - (72%)	Gaps:	1/334 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 STLQEGILVGCGNPLLDISAVVPLNFLQKYSMNEDDAILAEDRHMPIYGELVEGYQAEFLAGGSV 67
            |.|.|..|:|..||||||...|...||.|:.:.|:||||.:|:|..::.||...::.|::.||:.
Worm     2 SPLPENTLIGMCNPLLDIQTTVEKAFLDKWGLKENDAILCDDKHNDMFTELTRDFKVEYIPGGAA 66

  Fly    68 QNSLRIAQWILRQPRVAVFFGCVGEDRYANILKEKAQAAGLDVHYQVKKDVPTGTCAVLITGTHR 132
            |||||:|||||..|...||||.||:|:|.::|..||:.||::||||:.:.|.|||||.||.||||
Worm    67 QNSLRVAQWILNAPNRTVFFGAVGKDQYGDLLASKAKEAGVNVHYQINETVKTGTCAALINGTHR 131

  Fly   133 SLCANLAAANNFTIDHLEEPSNKALVDNAQYYYISGFFLTVNPPSIMQVAATAHAKQRPFLMNLS 197
            ||||:|||||.||.|||::..|:.:::.|:|:|::|||:||.||:|:|:|:.:....:.|.:|||
Worm   132 SLCAHLAAANTFTQDHLQKEENQKIIEQAKYFYVTGFFITVCPPAILQLASHSAEFNKTFTLNLS 196

  Fly   198 APFISQFYMAPLLAALPYVDIIFGNEAEAQAFAEAQQWPSGDLREIGKRLVAMEKKNPTRPRIAI 262
            |||||||:...|...:|.||::||||.||.|||:|..|.:..::||..:..|:.||: |:||:.:
Worm   197 APFISQFFFDKLSEIIPLVDVLFGNEDEAAAFAKANGWETTCVKEIALKAAALPKKS-TKPRLVV 260

  Fly   263 LTQGCDPVLLIQQDSVQEFPVTKLAVHEIVDTNGAGDAFVGGFLSQFVQGKSLDVCIRCGNYAAG 327
            .|||.:||::::.|.|.|||||:|...||||||||||||||||||||:|||.::..:.||:|||.
Worm   261 FTQGPEPVIVVEGDKVTEFPVTRLPKEEIVDTNGAGDAFVGGFLSQFIQGKGVEASVTCGSYAAQ 325

  Fly   328 HIIKNPGCT 336
            .|||..|||
Worm   326 EIIKKHGCT 334

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AdenoK	NP_001287054.1	PTZ00247	10..343	CDD:240328	173/327 (53%)
AdenoK	NP_001287054.1	ribokinase_pfkB_like	14..343	CDD:294126	171/323 (53%)
adk-1	NP_502104.1	ribokinase_pfkB_like	12..341	CDD:381848	171/324 (53%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160159974
Domainoid	1	1.000	345	1.000	Domainoid score	I561
eggNOG	1	0.900	-	-		E1_COG0524
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H4891
Inparanoid	1	1.050	371	1.000	Inparanoid score	I1223
Isobase	1	0.950	-	0	Normalized mean entropy	S836
OMA	1	1.010	-	-		QHG53733
OrthoDB	1	1.010	-	-		D1226324at2759
OrthoFinder	1	1.000	-	-		FOG0003751
OrthoInspector	1	1.000	-	-		oto19276
orthoMCL	1	0.900	-	-		OOG6_100649
Panther	1	1.100	-	-	O	PTHR45769
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R25
SonicParanoid	1	1.000	-	-		X2162
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	16	15.790