Protein Alignment Adk2 and ADK

DIOPT Version :10

• Sequence 1: NP_648624.1
• Gene: Adk2 / 39479
• FlyBaseID: FBgn0036337
• Length: 345
• Species: Drosophila melanogaster
• Sequence 2: NP_006712.2
• Gene: ADK / 132
• HGNCID: 257
• Length: 362
• Species: Homo sapiens
• Alignment Length: 341
• Identity: 179/341 - (52%)
• Similarity: 233/341 - (68%)
• Gaps: 2/341 - (0%)

  Fly     5 LQEGILVGCGNPLLDISAVVPLNFLQKYSMNEDDAILAEDRHMPIYGELVEGYQAEFLAGGSVQN 69
            |:|.||.|.|||||||||||..:||.|||:..:|.|||||:|..::.|||:.::.|:.||||.||
Human    21 LRENILFGMGNPLLDISAVVDKDFLDKYSLKPNDQILAEDKHKELFDELVKKFKVEYHAGGSTQN 85

  Fly    70 SLRIAQWILRQP-RVAVFFGCVGEDRYANILKEKAQAAGLDVHYQVKKDVPTGTCAVLITGTHRS 133
            |:::|||:::|| :.|.||||:|.|::..|||.||..|.:|.||..:.:.||||||..|||.:||
Human    86 SIKVAQWMIQQPHKAATFFGCIGIDKFGEILKRKAAEAHVDAHYYEQNEQPTGTCAACITGDNRS 150

  Fly   134 LCANLAAANNFTID-HLEEPSNKALVDNAQYYYISGFFLTVNPPSIMQVAATAHAKQRPFLMNLS 197
            |.|||||||.:..: ||:...|..||:.|:..||:||||||:|.|:::||..|....|.|.:|||
Human   151 LIANLAAANCYKKEKHLDLEKNWMLVEKARVCYIAGFFLTVSPESVLKVAHHASENNRIFTLNLS 215

  Fly   198 APFISQFYMAPLLAALPYVDIIFGNEAEAQAFAEAQQWPSGDLREIGKRLVAMEKKNPTRPRIAI 262
            ||||||||...|:..:|||||:||||.||..||..|.:.:.|::||.|:..|:.|.|..|.||.|
Human   216 APFISQFYKESLMKVMPYVDILFGNETEAATFAREQGFETKDIKEIAKKTQALPKMNSKRQRIVI 280

  Fly   263 LTQGCDPVLLIQQDSVQEFPVTKLAVHEIVDTNGAGDAFVGGFLSQFVQGKSLDVCIRCGNYAAG 327
            .|||.|..::..:..|..|.|......||:||||||||||||||||.|..|.|..|||.|:|||.
Human   281 FTQGRDDTIMATESEVTAFAVLDQDQKEIIDTNGAGDAFVGGFLSQLVSDKPLTECIRAGHYAAS 345

  Fly   328 HIIKNPGCTYSGEPEF 343
            .||:..|||:..:|:|
Human   346 IIIRRTGCTFPEKPDF 361

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Adk2	NP_648624.1	ribokinase_pfkB_like	14..343	CDD:469648	173/330 (52%)
ADK	NP_006712.2	Nuclear localization signal. /evidence=ECO:0000269|PubMed:19635462	8..16
		ribokinase_pfkB_like	29..361	CDD:469648	173/331 (52%)