Protein Alignment Icmt and STE14

DIOPT Version :10

• Sequence 1: NP_648623.1
• Gene: Icmt / 39478
• FlyBaseID: FBgn0036336
• Length: 299
• Species: Drosophila melanogaster
• Sequence 2: NP_010698.1
• Gene: STE14 / 852019
• SGDID: S000002818
• Length: 239
• Species: Saccharomyces cerevisiae
• Alignment Length: 227
• Identity: 85/227 - (37%)
• Similarity: 139/227 - (61%)
• Gaps: 8/227 - (3%)

  Fly    73 VLRNHDYQVAIRASFLGFAMAVSVLVICFAPTEWQQFGAYGCFMSLFHYSEFLVIAFANPRTLSL 137
            :.||..::|.:.:..||  :.:.:.|..|....::.|..:...:||||:.|:.:.|..||..:..
Yeast    15 IRRNPLHEVTMTSYILG--ILLGIFVGLFPQIRFKNFNLFIIALSLFHFLEYYITAKYNPLKVHS 77

  Fly   138 DSFMLNHSVHYGLAAAASWIEFSLEVYYLPQFKRYGY------IWVAGVVLCLLGEMVRKAAIIT 196
            :||:||:...|..|.:.:.:|..:|.:..|..|.:.|      ..|.|.:|.:||:..|..|:.|
Yeast    78 ESFLLNNGKSYMAAHSFAILECLVESFLFPDLKIFSYSLATKLCTVLGCLLVILGQYTRTIAMHT 142

  Fly   197 AGRSFTHLVQNEKHSEHKLITSGIYAYCRHPSYVGWFWWSIGTQIVLLNPICICIYTLVSWLFFH 261
            ||.||:|:|:.:|.|:|.|:.:|:|::.|||||:|:|||:||||::||||:.:.|:..|.|.||.
Yeast   143 AGHSFSHIVKTKKESDHVLVKTGVYSWSRHPSYLGFFWWAIGTQLLLLNPLSLVIFIFVLWKFFS 207

  Fly   262 DRIYVEEYSLLNFFQSDYVRYQKRVPTGLPFI 293
            |||.|||..|:.||.::|:.|:.:|..|:|||
Yeast   208 DRIRVEEKYLIEFFSAEYIEYKNKVGVGIPFI 239

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Icmt	NP_648623.1	ICMT	179..271	CDD:427740	47/91 (52%)
STE14	NP_010698.1	ICMT	127..219	CDD:427740	47/91 (52%)