Protein Alignment Icmt and Icmt

DIOPT Version :10

• Sequence 1: NP_648623.1
• Gene: Icmt / 39478
• FlyBaseID: FBgn0036336
• Length: 299
• Species: Drosophila melanogaster
• Sequence 2: NP_598549.1
• Gene: Icmt / 57295
• MGIID: 1888594
• Length: 284
• Species: Mus musculus
• Alignment Length: 299
• Identity: 146/299 - (48%)
• Similarity: 200/299 - (66%)
• Gaps: 20/299 - (6%)

  Fly     2 CAKSRVASPGAGGTSLCSEGRISLYCFLITAALVLIPSVPQ-NLYGVVPQVWGAVLWGPFLYYAL 65
            || :|| .||       ||.|:||..||:.|:::.:|.:.: .|.|..         |..||.|.
Mouse     4 CA-ARV-PPG-------SEARLSLATFLLGASVLALPLLTRAGLQGRT---------GLALYVAG 50

  Fly    66 INMIIRFVLRNHDYQVAIRASFLGFAMAVSVLVICFAPTEWQQFGAYGCFMSLFHYSEFLVIAFA 130
            :|.::..:.|...||:||||.||||.....|| :.|:.:.|..||.|.|.:|||||||:||.|..
Mouse    51 LNALLLLLYRPPRYQIAIRACFLGFVFGCGVL-LSFSQSSWNHFGWYVCSLSLFHYSEYLVTAVN 114

  Fly   131 NPRTLSLDSFMLNHSVHYGLAAAASWIEFSLEVYYLPQFKRYGYIWVAGVVLCLLGEMVRKAAII 195
            ||::||||||:||||:.|.:||.:|||||:||..:.|:.|:..::...|:::.:.||.:||||:.
Mouse   115 NPKSLSLDSFLLNHSLEYTVAALSSWIEFTLENIFWPELKQITWLSATGLLMVVFGECLRKAAMF 179

  Fly   196 TAGRSFTHLVQNEKHSEHKLITSGIYAYCRHPSYVGWFWWSIGTQIVLLNPICICIYTLVSWLFF 260
            |||.:|.|:||:||...|.|:|||:||:||||||||||:||||||::|.||||..:|.|..|.||
Mouse   180 TAGSNFNHVVQSEKSDTHTLVTSGVYAWCRHPSYVGWFYWSIGTQVMLCNPICGVVYALTVWRFF 244

  Fly   261 HDRIYVEEYSLLNFFQSDYVRYQKRVPTGLPFIRGYLVD 299
            .||...||.||::||..:|:.|:||||||||||:|..|:
Mouse   245 RDRTEEEEISLIHFFGEEYLDYKKRVPTGLPFIKGVKVE 283

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Icmt	NP_648623.1	ICMT	179..271	CDD:427740	53/91 (58%)
Icmt	NP_598549.1	ICMT	163..257	CDD:427740	49/93 (53%)