Protein Alignment Icmt and icmt-1

DIOPT Version :10

• Sequence 1: NP_648623.1
• Gene: Icmt / 39478
• FlyBaseID: FBgn0036336
• Length: 299
• Species: Drosophila melanogaster
• Sequence 2: NP_491473.1
• Gene: icmt-1 / 172106
• WormBaseID: WBGene00017673
• Length: 295
• Species: Caenorhabditis elegans
• Alignment Length: 286
• Identity: 119/286 - (41%)
• Similarity: 168/286 - (58%)
• Gaps: 30/286 - (10%)

  Fly    22 RISLYCFLITAALVLIPSVPQNLYGVVPQVWGAVLWGPFLYYALINMIIRFV----------LRN 76
            |.:::.|:  |:..:|.:|             |.:.|.||...|.::|:..|          :.|
 Worm    26 RTAIFAFI--ASFTVIAAV-------------ASVTGSFLVGLLASVIVLLVAYAVGESCEFINN 75

  Fly    77 HDYQVAIRASFLGFAMAVS-VLVICFAPTEWQQFGAYGCFMSLFHYSEFLVIAFANPRTLSLDSF 140
               |:.:.|:|||.|:||: |..:......|:.|..|..|:|:||:|||:..|..|.|||..|||
 Worm    76 ---QILMPAAFLGCAVAVNLVYTVAHEGELWEYFSRYFLFLSVFHFSEFVFTALTNRRTLGPDSF 137

  Fly   141 MLNHSVHYGLAAAASWIEFSLEVYYLPQFKRYGYIWVAGVVLCLLGEMVRKAAIITAGRSFTHLV 205
            :|.||..|.|||:..||||.:|..:.|:.|.|..:|: |...|::||:|||..::.||.:||||:
 Worm   138 LLKHSFGYWLAASIGWIEFLIEANFYPEIKMYSVLWI-GTFGCIIGEIVRKVGMVHAGLAFTHLM 201

  Fly   206 QNEKHSEHKLITSGIYAYCRHPSYVGWFWWSIGTQIVLLNPICICIYTLVSWLFFHDRIYVEEYS 270
            ...|.|.|.||.:|||||.|||.|.|||.|::.|||||.|||...|||.|:|.||.:||.:||..
 Worm   202 ARTKRSGHTLINTGIYAYMRHPGYFGWFIWAVSTQIVLCNPISFVIYTFVTWRFFANRIEIEEKD 266

  Fly   271 LLNFFQSDYVRYQKRVPTGLPFIRGY 296
            |::||..||..||::..:|:||.|||
 Worm   267 LISFFGDDYAEYQRKTWSGVPFARGY 292

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Icmt	NP_648623.1	ICMT	179..271	CDD:427740	50/91 (55%)
icmt-1	NP_491473.1	ICMT	179..269	CDD:427740	50/89 (56%)