Protein Alignment MICAL-like and micall2

DIOPT Version :10

• Sequence 1: NP_648621.1
• Gene: MICAL-like / 39475
• FlyBaseID: FBgn0036333
• Length: 1010
• Species: Drosophila melanogaster
• Sequence 2: NP_001072513.1
• Gene: micall2 / 779968
• XenbaseID: XB-GENE-979747
• Length: 1023
• Species: Xenopus tropicalis
• Alignment Length: 1155
• Identity: 289/1155 - (25%)
• Similarity: 451/1155 - (39%)
• Gaps: 337/1155 - (29%)

  Fly    14 KALEYWCRVVTQGYNGVKVENMTTSWRNGLAFCAIIHHFRPDLIDFDRLKADDIYENNDLAFTTA 78
            |||:.||:....||..|.:.|||||:|:|||||||:|..|||||:||.|..:::|:||.:||:.|
 Frog     5 KALQQWCKQQCDGYRDVSITNMTTSFRDGLAFCAILHKHRPDLINFDLLSKENVYDNNHMAFSVA 69

  Fly    79 EKYLGIPALLDAADMVSYEVPDRLSILTYLSQFYKVL-GKS-------LKHPKP---EEPLGEE- 131
            |:.|||||||||.|||...||||||||||:||:|... |:|       :|.|.|   |||.|::
 Frog    70 EEKLGIPALLDAEDMVKLRVPDRLSILTYVSQYYNYFHGRSPIGGLAGVKRPPPDTVEEPAGKKV 134

  Fly   132 -----------SEPPQKVMH-----------IVGMPRR-------------DKCQKCNLPVFLAE 161
                       |..||.|..           |...|.|             ..|..|...|.|.:
 Frog   135 TNDVLPTPQATSRAPQPVPRTNVPVLKSNTVIENPPVRAGIREIDSNSSVSSNCMICGKHVHLVQ 199

  Fly   162 RVLVGKRAYHRTCLKCARCSSLLTPGSFYETEVNNIYCC-------ETCP--------------- 204
            |.:...:.|||.|.||.:||..|.||.:...:....:.|       .|.|
 Frog   200 RHMADGKLYHRNCFKCKQCSRTLQPGQYKAGDGLGSFICTNHHIAVPTSPVTRTIMPAAPHGATV 264

  Fly   205 DEESE----PESDILK--------------LKTTTTDSPNDKQMVA-----QSSDYSEAEDKQED 246
            ||:..    |.|.:|.              |.|.....|.::..|.     |...:|.....|||
 Frog   265 DEKKSSWVTPRSAVLDQNNKTPGNRFDHSGLGTGAVQDPTNRTAVGFVSNNQKLQHSTGAPAQED 329

  Fly   247 LEDNDIRTTDKPENFQPPSN--------KDEQNNELTI-----NPV-NPILSEERKISFIPLDEE 297
            ....:|  .:.|.:....|.        || .::.:||     |.| |..|:..|.::.....:.
 Frog   330 KPSRNI--LNSPYSSSSTSTAVGFGNSIKD-NSSTITIGSNQQNKVDNNYLNTSRSVAHEQPKKP 391

  Fly   298 DGGLIEQYNKSTTPVKPAIPEKPKV---------------STLPLDDEQHAGVEQNNDLAVSPEN 347
            ...|:....|| .|.|..:|...::               :||...||              |:.
 Frog   392 SSDLLTHKGKS-EPQKDPLPSNQQIKSPNFTINSISAGRMTTLVTKDE--------------PKE 441

  Fly   348 DIPKEKLKISSVSIYLEDDRLVVDAIHPDNLDKQEALNNTSDALIPESQEAPIPENNTQVAIKPE 412
            ..|| ..::|:..                |...:|....||.|::.       |.|.    :...
 Frog   442 TSPK-PWELSAAK----------------NKAARERFFQTSPAVVE-------PANK----VSSR 478

  Fly   413 DHISPRKENKIFSNTESCSKQEGVLPKQMDLESPKDKVIETKASETDYPEDLNPFKDDD------ 471
            |.:||:..:....:|.| |...|:.....:.::.::.:::|....|. |:.....::..
 Frog   479 DVVSPKSSDGPGKSTAS-SLSPGITDSSTEKDNARNYLLKTLGGPTS-PKPSGEAENPSPVYRPH 541

  Fly   472 ---SSKGANPFDSSDDEVELLKAIPAQQSKGK------VVPPRP--PPPKIGLSSISNPSEKPHS 525
               :.|.|:|.:|| .:||..:.:| ::.|.|      |:.|.|  ..|......|:.||....|
 Frog   542 RLLNEKTADPSNSS-TKVEPARPVP-KERKNKNDTAKAVLNPEPLLTTPTYSSKGITTPSTGNSS 604

  Fly   526 SPTLSHGKKMPMPTPRISISKTQTPAKPMTHQGQKSSISSSSSEHLNSIRTFDRGADDRGSSISL 590
            |.|    |.:..|:...|.|.|:..:.|:|.       ||||:.                ..|:.
 Frog   605 STT----KGITTPSSGNSSSTTKGISTPITG-------SSSSTT----------------KGITT 642

  Fly   591 PSANGPRKPLRASVGSPLRSEESSPTTSLSSITSPMRKKRQAPLPPIQTDFDSDPGFSKLSDEQK 655
            || :|........:.||:....||.|.|..|.:.|.::..:.          |..|
 Frog   643 PS-SGNSSSTTKGISSPITGNGSSTTKSYLSKSGPGQRAEEI----------SSKG--------- 687

  Fly   656 ALLHTQLKAPNLGDSTRRLIPLDQSLLSDEATESSNYDESLS-TSNADEEVNVVYRRILVPPTQP 719
                                |:..|.:|.:.| ..|:.::|. .:...:...||..::...|...
 Frog   688 --------------------PVPNSNVSKQET-PENWRQNLKPIAKTPQTPGVVQPKVYPLPKDV 731

  Fly   720 ENTVERSKEDQKSPIVYNDFDRNVS-PLGHNKS----THGKWKRRKGPAPAVPIPPRKVL----- 774
            ||..:.:...||:|.:.|.....:: |...||.    |....|.::..|.:.|.||||.|
 Frog   732 ENAAKTTPSPQKTPTIINSVKTTLNFPGKENKPSECLTPPAAKSKEDKASSSPTPPRKKLLPVNL 796

  Fly   775 ----------------------------------------------QRLPLQEIRHEFEIIAVQQ 793
                                                          :.:|.:||:.:.:||..:.
 Frog   797 DLINDWPKPVQKWQDVSLKDDTKRPAAHSSVNERSKNDASRNKARPEYIPKEEIQRQLQIIEQEL 861

  Fly   794 LGLEKQGVILEKMIRDRCERSLDATDTDGPESAEVLTNSKEVEDLILQLFELVNEKNELFRRQAE 858
            ..||:|||.:||.:|. |         ||.||.:.         |::..|:|::||..|.|:::|
 Frog   862 DALEQQGVEMEKQLRS-C---------DGDESEDT---------LMVDWFKLIHEKQLLLRQESE 907

  Fly   859 LMYLRRQHRLEQEQADIEHEIRVLMGQPEHNKTDSDKAHEEVLINRLVKVVEMRNEVIDSLETDR 923
            |.|:.:|..||.:|::::.|:|.||.:|:..||.:|:..|:.|:::|:.:|..|:.:::.|:.||
 Frog   908 LNYISKQQALEDKQSNVDTELRNLMNKPDDLKTPADREREKQLLDQLLVIVNDRSGIVECLDEDR 972

  Fly   924 VREARED--MSIKNRLHIYNSERE---EPPAHPRSADKSSKKLSKKERKK 968
            :||..||  |....:.|..|.::|   ||....||....|.....|::.|
 Frog   973 IREKEEDEIMEAMIQRHSENHQKEASPEPNLKRRSRFSFSGLFKPKDKSK 1022

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MICAL-like	NP_648621.1	CH_MICALL2	11..115	CDD:409102	62/100 (62%)
		LIM_like_1	146..207	CDD:188784	21/95 (22%)
		PTZ00449	<411..727	CDD:185628	66/333 (20%)
		bMERB_dom	785..933	CDD:463467	50/149 (34%)
micall2	NP_001072513.1	CH_MICALL2	2..107	CDD:409102	62/101 (61%)
		LIM_Mical_like_1	188..242	CDD:188828	17/53 (32%)
		Herpes_BLLF1	<396..785	CDD:282904	96/503 (19%)
		bMERB_dom	853..980	CDD:463467	48/145 (33%)