Protein Alignment MICAL-like and micall1

DIOPT Version :10

• Sequence 1: NP_648621.1
• Gene: MICAL-like / 39475
• FlyBaseID: FBgn0036333
• Length: 1010
• Species: Drosophila melanogaster
• Sequence 2: XP_002934280.2
• Gene: micall1 / 779550
• XenbaseID: XB-GENE-493743
• Length: 802
• Species: Xenopus tropicalis
• Alignment Length: 1033
• Identity: 272/1033 - (26%)
• Similarity: 407/1033 - (39%)
• Gaps: 307/1033 - (29%)

  Fly    11 TGTKALEYWCRVVTQGYNGVKVENMTTSWRNGLAFCAIIHHFRPDLIDFDRLKADDIYENNDLAF 75
            :.::.|:.||....:||.|:.:.::::|:|:||||||:||..||||||||.|..::::|||.|||
 Frog     2 SASRNLQQWCSRQCEGYPGILIYDLSSSFRDGLAFCALIHRHRPDLIDFDSLSKENVFENNRLAF 66

  Fly    76 TTAEKYLGIPALLDAADMVSYEVPDRLSILTYLSQFYKVLGKSLKHPKPEEPLGEESEPPQKVMH 140
            ..||:.||||||||..||||.:|||||||:|||||:|.....|....||:  |.|.||.|.|...
 Frog    67 EVAERELGIPALLDPEDMVSMKVPDRLSIMTYLSQYYNHFRNSSPVGKPQ--LKETSESPSKEPS 129

  Fly   141 IVGMPR--------------RDKCQKCNLPVFLAERVLVGKRAYHRTCLKCARCSSLLTPGSFYE 191
            ...:|:              ...|..|...|.|.:|.||..:.|||.|.:|..|||.|.||::..
 Frog   130 GGSLPQGSPNAQTSLIRSSISSTCALCQQHVHLVQRYLVEGKLYHRQCFRCKECSSTLVPGAYRP 194

  Fly   192 -TEVNNIYCCETCPDEESEPESDILKLKTTTTDSPNDKQMVAQSSDYSEAEDKQEDLEDNDIRTT 255
             |:...:.|...|
 Frog   195 GTDAGTLVCTHHC---------------------------------------------------- 207

  Fly   256 DKPENFQPPSNKDEQNNELTINPVNPILSEERKISFIPLDEEDGGLIEQYNKSTTPVKPAIPEKP 320
                 .:||::.                         |..||||   .:.....||.||.:||||
 Frog   208 -----HRPPTSS-------------------------PESEEDG---TKQKAVQTPPKPFVPEKP 239

  Fly   321 KVSTLPLDDEQHAGVEQNNDLAVSPENDIPKEKLKISSVSIYLEDDRLVVDAIHPDNLDKQEALN 385
            ..|..|                       |.|                    :|||.
 Frog   240 ASSNKP-----------------------PTE--------------------LHPDP-------- 253

  Fly   386 NTSDALIPESQEAPIPENNTQVAIKPEDHISPRKENKIFSNTESCSKQEGVLPKQM---DLESPK 447
                  .|..:..|.|...:.||.:|    .||        :.:.::...|.|..:   :.:||.
 Frog   254 ------FPNMRPVPAPRRTSDVAPQP----LPR--------SRAAAESSPVRPTSLINGEQQSPA 300

  Fly   448 DKVIETKASETDYPEDLNPFKDDDSSKGANPFDSSDDEVELLKAIPAQQSKGKVVPPRPP---PP 509
            ..:.:.::.:.      :..::|:..:..||        ..|..:||.:.|.:..||.||   .|
 Frog   301 PPIPKPRSRQR------SSEREDEEKQKKNP--------PWLSLVPATEPKRRAAPPPPPLAQKP 351

  Fly   510 KIG---------------LSS---ISNP---SEKPHSSPTLSHGKKMPMPTPRISISKTQTPAKP 553
            ::|               |||   ..||   .|:...:.:|..|.      |...|:.|.:| |.
 Frog   352 ELGDEKSQKSLNDTEKQSLSSKPTAYNPFEDEEEEAETSSLKPGH------PWYGITPTSSP-KS 409

  Fly   554 MTHQGQKSSISSSSSEHLNSIRTFDRGADDRGSSISLPSANGPRKPLRASVGSPLRSEESSPTTS 618
            ......|:..:|..:.|.|.:...         |.|.|.:..|         ||..|.||.||.:
 Frog   410 RKRLAPKAPNASPLAHHSNLVSRL---------SHSEPPSGSP---------SPALSTESLPTDA 456

  Fly   619 LSSITSPMRKKRQAPLPPIQTDFDSDPGFSKLSDEQKALLHTQLKAPNLGDSTRRLIPLDQSLL- 682
            .:....|....:.:..|.|.:....:|     ||....   |.|.......||...:.....|.
 Frog   457 STKGQDPESVPKSSSEPTIHSPNKPEP-----SDRDTT---TYLSTGVPSTSTNTSLSSSSELAN 513

  Fly   683 SDEATESSNYDESLSTSNADEEVNVVYRRILVPPTQPENTVERSKEDQKSPIV-----YNDFDRN 742
            ::||.||.:.:..||.|....:|..:        :.|......|...:|.|:.     .|.|:|.
 Frog   514 TNEAQESPSPEMPLSPSRPAPQVPTI--------SIPSTVASDSTPPEKKPLAKQICKQNPFNRK 570

  Fly   743 VSPLGH--NKSTHGKWKRRKGPAPAVPIPP--------RKVL--QRLPLQEIRHEFEIIAVQQLG 795
            .||...  ||      :.:|||.|:.|..|        |||.  ..:|..||:.|.|.|.::...
 Frog   571 SSPATSPINK------RNQKGPKPSRPPAPGHGFPLIKRKVQADDYIPEDEIQMEMETIELRLDE 629

  Fly   796 LEKQGVILEKMIRDRCERSLDATDTDGPESAEVLTNSKEVEDLILQLFELVNEKNELFRRQAELM 860
            ||::||.||..:|.                   |.|..:.:.|::..|:|:.||:.|.||::||:
 Frog   630 LERRGVELEHRLRK-------------------LENESDEDSLLVDWFKLIQEKHTLVRRESELV 675

  Fly   861 YLRRQHRLEQEQADIEHEIRVLMGQPEHNKTDSDKAHEEVLINRLVKVVEMRNEVIDSLETDRVR 925
            |..:|..|||.|||:|:|:|.|:.:||.:..:.||..|:||:..||.::|.||.::..|:.||.|
 Frog   676 YTTKQQSLEQRQADVEYELRCLLNKPEKDWLEEDKEREQVLMQELVTLIEQRNAIVKCLDEDRQR 740

  Fly   926 EARED-----MSIKNRLHIYNSEREEPPAHPRSADKSSKKLSKKERKKL---KEENKL 975
            |..||     |.:|...|....::::....|   .|..|.||.|:..|:   |::||:
 Frog   741 EKEEDKIIEAMILKKDFHTDPQKKKKGKFKP---IKVLKLLSPKQEPKVKSPKDKNKV 795

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MICAL-like	NP_648621.1	CH_MICALL2	11..115	CDD:409102	58/103 (56%)
		LIM_like_1	146..207	CDD:188784	21/75 (28%)
		PTZ00449	<411..727	CDD:185628	68/343 (20%)
		bMERB_dom	785..933	CDD:463467	54/152 (36%)
micall1	XP_002934280.2	CH_MICALL1	3..109	CDD:409101	58/105 (55%)
		LIM_Mical_like_1	153..207	CDD:188828	20/53 (38%)
		PHA03247	<230..594	CDD:223021	102/493 (21%)
		bMERB_dom	619..748	CDD:463467	53/147 (36%)