Protein Alignment MICAL-like and Actn4

DIOPT Version :10

• Sequence 1: NP_648621.1
• Gene: MICAL-like / 39475
• FlyBaseID: FBgn0036333
• Length: 1010
• Species: Drosophila melanogaster
• Sequence 2: XP_008757407.1
• Gene: Actn4 / 63836
• RGDID: 61816
• Length: 933
• Species: Rattus norvegicus
• Alignment Length: 862
• Identity: 189/862 - (21%)
• Similarity: 295/862 - (34%)
• Gaps: 274/862 - (31%)

  Fly    14 KALEYWCRVVTQGYNGVKVENMTTSWRNGLAFCAIIHHFRPDLIDFDRLKADDIYENNDLAFTTA 78
            :.|..||:..|..|..|.|:|...||::||||.|:||..||:||::|:|:.||...|.:.||..|
  Rat   167 EGLLLWCQRKTAPYKNVNVQNFHISWKDGLAFNALIHRHRPELIEYDKLRKDDPVTNLNNAFEVA 231

  Fly    79 EKYLGIPALLDAADMVSYEVPDRLSILTYLSQFYKVLGKSLKHPKPEEPLGEESEPPQKVMHIVG 143
            ||||.||.:|||.|:|:...||..:|:||:|.||.....:.|
  Rat   232 EKYLDIPKMLDAEDIVNTARPDEKAIMTYVSSFYHAFSGAQK----------------------- 273

  Fly   144 MPRRDKCQKCNLPVFLAERVLVGKRAYHRTCLKCARCSSLLTPGSFYETEVNNIYCCETCPDEES 208
                                                          .||..|.| |.....::|:
  Rat   274 ----------------------------------------------AETAANRI-CKVLAVNQEN 291

  Fly   209 EP--------ESDILKLKTTTTDSPNDKQMVAQSSDYSEAEDKQEDLED-NDIRTTDKPENFQPP 264
            |.        .||:|:....|.....|:  |.|.:    .::.|:.||| .|.|...|     ||
  Rat   292 EHLMEDYERLASDLLEWIRRTIPWLEDR--VPQKT----IQEMQQKLEDFRDYRRVHK-----PP 345

  Fly   265 SNKDEQNNELTINPVNPILSEERKISFIP---------------LDEEDGG-------------- 300
            ..:::...|:..|.:...|....:.:|:|               |::.:.|
  Rat   346 KVQEKCQLEINFNTLQTKLRLSNRPAFMPSEGRMVSDINNGWQHLEQAEKGYEEWLLNEIRRLER 410

  Fly   301 ---LIEQY------NKSTTPVKPAIPEKPKVSTLPLDD-----EQHAGVEQNNDLAVSPEN---- 347
               |.|::      :::.|..|.|:.:.....|..|.|     .:|...|  :|||...:.
  Rat   411 LDHLAEKFRQKASIHEAWTDGKEAMLKHRDYETATLSDIKALIRKHEAFE--SDLAAHQDRVEQI 473

  Fly   348 -DIPKEKLKISSVSIYLEDDRLVVDAIHPDNL-----DKQEALNNTS------DALIPESQEAPI 400
             .|.:|..::.....:..:.|........|||     .::|||..|.      |.|..|..:...
  Rat   474 AAIAQELNELDYYDSHNVNTRCQKICDQWDNLGSLTHSRREALEKTEKQLETIDQLHLEYAKRAA 538

  Fly   401 PENNTQVAIKPED-------HISPRKENKIFSNTESCSKQEGVLPKQMDLESPKDKVIETKASET 458
            |.||...:.. ||       |.....|..|.::.:.    :..||   |.:..::.::... .|.
  Rat   539 PFNNWMESAM-EDLQDMFIVHTIEEIEGLISAHDQF----KSTLP---DADREREAILAIH-KEA 594

  Fly   459 DYPEDLNPFKDDDSSKGANPFDSSDDEVELLKAIPAQQSKGKVVPPRPPPPKIGLSSISNPSEKP 523
            ....:.|..|    ..|:||:.|...::...|....||    :||.|.       .::.....|.
  Rat   595 QRIAESNHIK----LSGSNPYTSVTPQIINSKWEKVQQ----LVPKRD-------HALLEEQSKQ 644

  Fly   524 HSSPTL--SHGKKMPMPTP----------RISISKTQTPAKPMTH--QGQKSSI----------- 563
            .|:..|  ....:..|..|          ||||....|....::|  |.::|.:
  Rat   645 QSNEHLRRQFASQANMVGPWIQTKMEEIGRISIEMNGTLEDQLSHLKQYERSIVDYKPNLDLLEQ 709

  Fly   564 ---------------SSSSSEHL-----NSIRTFDRGADDRGSSISLPSANG----PRKPLRASV 604
                           ::.:.|||     ..:.|..|..::..:.|....|.|    ..:..|||.
  Rat   710 QHQLIQEALIFDNKHTNYTMEHLRVGWEQLLTTIARTINEVENQILTRDAKGISQEQMQEFRASF 774

  Fly   605 -------GSPLRSEESSPTTSLSSITSPMRKKRQAPLPPIQTDFDSDPGFSKLSDEQKALLHTQL 662
                   |..|..||..  ..|.|:...:...||.     ||.       |..||:.:|||.:
  Rat   775 NHFDKDHGGALGPEEFK--ACLISLGYDVENDRQK-----QTG-------SMDSDDFRALLIS-- 823

  Fly   663 KAPNLGDSTRRLI-----PLDQSLLSDEATESSNYDESLSTSNADEEV----------NVV---- 708
            ...:|||:....|     |....|::.:|.......|:..|..||:.:          |.:
  Rat   824 TGYSLGDAEFNRIMSVVDPNHSGLVTFQAFIDFMSRETTDTDTADQVIASFKVLAGDKNFITAEE 888

  Fly   709 YRRILVPPTQPENTVER 725
            .||.| ||.|.|..:.|
  Rat   889 LRREL-PPDQAEYCIAR 904

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MICAL-like	NP_648621.1	CH_MICALL2	11..115	CDD:409102	48/100 (48%)
		LIM_like_1	146..207	CDD:188784	5/60 (8%)
		PTZ00449	<411..727	CDD:185628	81/397 (20%)
		bMERB_dom	785..933	CDD:463467
Actn4	XP_008757407.1	CH_ACTN_rpt1	47..151	CDD:409063
		CH_ACTN_rpt2	155..269	CDD:409065	48/101 (48%)
		SPEC	296..517	CDD:238103	44/233 (19%)
		SPEC	414..640	CDD:238103	50/251 (20%)
		SPEC	532..754	CDD:238103	43/245 (18%)
		PTZ00184	759..>890	CDD:185504	33/146 (23%)
		EFhand_Ca_insen	863..929	CDD:430177	12/43 (28%)