Protein Alignment MICAL-like and micall2a

DIOPT Version :9

• Sequence 1: NP_648621.1
• Gene: MICAL-like / 39475
• FlyBaseID: FBgn0036333
• Length: 1010
• Species: Drosophila melanogaster
• Sequence 2: XP_005164253.1
• Gene: micall2a / 327198
• ZFINID: ZDB-GENE-030131-5409
• Length: 802
• Species: Danio rerio
• Alignment Length: 1090
• Identity: 246/1090 - (22%)
• Similarity: 374/1090 - (34%)
• Gaps: 430/1090 - (39%)

  Fly    14 KALEYWCRVVTQGYNGVKVENMTTSWRNGLAFCAIIHHFRPDLIDFDRLKADDIYENNDLAFTTA 78
            |||:.||::..:||..|.:.||:.|:|:||||||:||.||||||:|:.|..|::|.||.|||..|
Zfish     5 KALQQWCKIQCEGYRDVAISNMSMSFRDGLAFCALIHKFRPDLINFESLSKDNVYYNNHLAFRVA 69

  Fly    79 EKYLGIPALLDAADMVSYEVPDRLSILTYLSQFYKVL------------------GKSLKHPKPE 125
            |.:|||||||||.|||:..||||||||||:||:|...                  .|.:...|..
Zfish    70 EDHLGIPALLDAEDMVALPVPDRLSILTYVSQYYNYFHGRSPIGGVGGIKRHAEDSKEVPSEKKN 134

  Fly   126 EPL---------GEESEPPQKVM-------------------HIVGMPRR--------------- 147
            .|:         ..|:.|||..|                   |.:..|.|
Zfish   135 LPVVAKNHNLKTNTENRPPQSEMPKIINRPPSLNIQKSAPEKHALATPARQTGTDRQKSPGPKCV 199

  Fly   148 -------------------------------------DKCQKCNLPVFLAERVLVGKRAYHRTCL 175
                                                 .:|..|...|.|.:|.||..:.|||:|.
Zfish   200 QAPVTPLRARSPQPHREAEKVSKSVLVETSNKTGTLNSECAVCGNHVHLVQRHLVDGKLYHRSCY 264

  Fly   176 KCARCSSLLTPGSFYETEVNNIYCCETCPDEESEPESDILKLKT---TTTDSPNDKQMVAQSSDY 237
            ||:.|...|..|::..........|......::..:..:...|:   |.:|      :||:
Zfish   265 KCSVCYGTLKSGAYKLGSDTGSLVCTIHQHGQNGFKPTVKPFKSSGFTVSD------LVAK---- 319

  Fly   238 SEAEDKQEDLEDNDIRTTDKPENFQPPSNKDEQNNELTINPVNPILSEERKISFIPLDEEDGGLI 302
            ||.||:..  ....|.....|....|             .||...|:::   |:....:......
Zfish   320 SEREDQSP--SQRYISVLSAPIKAVP-------------RPVELSLAQQ---SWTSSAQRTQAAR 366

  Fly   303 EQYNKSTTPVKPAIPE-KPKVSTLPLDDEQHAGVEQNNDLAVSPENDIPKEKLKISSVSIYLEDD 366
            :::.:|..|.....|. ||     ||...:             |.|...:||          |.:
Zfish   367 QKFFQSCAPATELQPNTKP-----PLGPAE-------------PSNLKVQEK----------EGN 403

  Fly   367 RLVVDA--IHPDNLDKQEALNNTSDALIPESQEAPIPENNTQVAIKPEDHISPRKENKIFSNTES 429
            |.:.:.  :|..|.:...|||  ||           |...:||.|                   |
Zfish   404 RALANGNPLHEGNANNNNALN--SD-----------PRAKSQVKI-------------------S 436

  Fly   430 CSKQEGVLPKQMDLESPKDKVIETKASETDYPEDLNPFKDDDSSKGANPFDSSDDEVELLKAIPA 494
            ||..|                :.|...|....:          |||.:.:.::.....::.:...
Zfish   437 CSSAE----------------VSTWRQELHVRD----------SKGRSSYQAAPSSPAIISSGGG 475

  Fly   495 QQSKGKVVPPRPPPPKIGLSSISNPSEKPHSSPTLSHGKKMPMPTPRISISKTQTPAKPMTHQGQ 559
            ...|          ..:.||:||..|.:|   |:|                 .||.||...
Zfish   476 MNGK----------ESLYLSAISKESSRP---PSL-----------------LQTTAKASA---- 506

  Fly   560 KSSISSSSSEHLNSIRTFDRGADDRGSSISLPSANGPR----------KPLRASVGSPLRSEES- 613
                        |.::::|..||.|....:.|  ||||          .||.......|:.::|
Zfish   507 ------------NDVQSYDAPADWRSKPKAAP--NGPRLNRSPDIAKDVPLTCGENKDLKVQDSQ 557

  Fly   614 --------------------SPTTSLSSITSPMRKKRQAPLPPIQTDFDSDPGFSKLSDEQKALL 658
                                ||:||...::||
Zfish   558 AFMLNHSKGCNNDCSLASCVSPSTSCHKLSSP--------------------------------- 589

  Fly   659 HTQLKAPNLGDSTRRLIPLDQSLLSDEATESSNYDESLSTSNADEEVNVVYRRILVPPTQPENTV 723
                |.|..|.:|                  |:||..          |::...||:
Zfish   590 ----KQPRCGSAT------------------SSYDNG----------NILCNNILL--------- 613

  Fly   724 ERSKEDQKSPIVYNDFDRNVSPLGHNKSTHGKWKRRKGPAPAVPIPPRKVLQRLPLQEIRHEFEI 788
                .:.:||.....:                            |.|.::.:.  ||:|.:...
Zfish   614 ----HEARSPTTNTCY----------------------------ITPEQISKE--LQDIENNLN- 643

  Fly   789 IAVQQLGLEKQGVILEKMIRDRCERSLDATDTDGPESAEVLTNSKEVEDLILQLFELVNEKNELF 853
                  .||.:||.||..:|        ..:.:|  ..::|     ::.|::..|.|:.:|....
Zfish   644 ------DLENEGVELEWKLR--------VYEEEG--HGDIL-----MDPLMVDWFNLIRKKQSYI 687

  Fly   854 RRQAELMYLRRQHRLEQEQADIEHEIRVLMGQPEHNKTDSDKAHEEVLINRLVKVVEMRNEVIDS 918
            ||::||||:.|...||::|..:|.|:|.|:.:|||.||.::|..|..|:|||:|:|..||.:::.
Zfish   688 RRESELMYIARTQDLEEQQPGVEGELRRLINKPEHLKTLNEKKRETELLNRLMKIVNDRNAIVEG 752

  Fly   919 LETDRVREAREDMSIK---NRLHIYNSEREEPPAHPRSADKSSKKLSKKE 965
            ||.||:||..||..:.   .||.:...:.:...:..:...:.|||.|..|
Zfish   753 LEEDRIREEEEDQQLNEMMQRLGLQKFKNKRKSSFSKLFRRRSKKASMGE 802

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MICAL-like	NP_648621.1	CH	14..111	CDD:278723	60/96 (63%)
		LIM_like_1	146..207	CDD:188784	18/112 (16%)
		DUF3585	778..933	CDD:288945	53/154 (34%)
micall2a	XP_005164253.1	CH	5..102	CDD:278723	60/96 (63%)
		LIM_Mical_like_1	239..293	CDD:188828	17/53 (32%)
		DUF3585	627..753	CDD:288945	46/149 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	142	1.000	Domainoid score	I4623
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	277	1.000	Inparanoid score	I2900
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D186776at33208
OrthoFinder	1	1.000	-	-		FOG0002858
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X4926
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	6.060