DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment MICAL-like and pigs

DIOPT Version :9

Sequence 1:	NP_648621.1	Gene:	MICAL-like / 39475	FlyBaseID:	FBgn0036333	Length:	1010	Species:	Drosophila melanogaster
Sequence 2:	NP_001245550.1	Gene:	pigs / 31596	FlyBaseID:	FBgn0029881	Length:	977	Species:	Drosophila melanogaster

Alignment Length:	578	Identity:	110/578 - (19%)
Similarity:	188/578 - (32%)	Gaps:	162/578 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   242 DKQEDLEDNDIRTTDKPEN----FQPPSNKDEQNNELTINPVNPILSEERKISFIPLDEEDGGLI 302
            :|.|::.||....:|:...    .|..:.|.|.            |..:..|.    |.|....:
  Fly   530 NKFENISDNGSEISDEGYRSLGVIQSGAQKRES------------LHSQASIE----DAESNARL 578

  Fly   303 EQYNKSTTPVKPAIPEKPKVSTLPLDDEQHAGVEQNND-----LAVSPENDIP-----KEKL--K 355
            :| ..|.:.:.|:.....|.:|..|::|...|.::..|     :...|:: :|     ..||  |
  Fly   579 DQ-TSSDSQISPSDEPAEKATTDILEEEDLNGQDREEDQEDYSVCDGPQS-LPAILSGAHKLSDK 641

  Fly   356 ISSVSIYLEDDRLVVDAIHPDNLDKQEALNNTSDALIPESQEAPIPENNTQVAIKPEDHISPRKE 420
            .....:::.||.:.||            :..|.|..:..:...|.| |.:::   |...::.|:.
  Fly   642 FEQSGVFITDDEITVD------------IAKTEDQSVANTMGNPTP-NLSKI---PRSPLAQRRR 690

  Fly   421 NKIFSNTESCSKQEGVLPKQMDLESPKDKVIETKASETDYPEDLNPFKDDDSSKGANPFDSSDDE 485
            ..|.::|  |....|.|                        :||       ||:...|..:...:
  Fly   691 RSIDNST--CGGAGGSL------------------------QDL-------SSRSGLPAPAFSRK 722

  Fly   486 VELLKAIPAQQSKGKVVPPRPPP--------PKIGLSSISNPSEKPHSSPTLSHGKKMPMPTPRI 542
            ..:.:::..:.|.|....|..||        |.:  ..::|    ..|..|....|:.|..|
  Fly   723 QPVYRSVRTRNSTGATTTPVAPPRSRQATQLPMV--RDVTN----TWSGRTTGAPKRRPPCT--- 778

  Fly   543 SISKTQTPAKPMTHQGQKSSISSSSSEHLNSIRTFDRGADDRGSSISLPSANGPRKPLRASVGSP 607
                ..|...|....|...|              |:|....|.|.| |..:||.|
  Fly   779 ----ADTFVAPTNGTGPAGS--------------FERNGKGRSSQI-LYDSNGRR---------- 814

  Fly   608 LRSEESSPTTSLSSITSPMRKKRQAPLPPIQTDFDSDPGFSKLSDEQKALLHTQLKAPNLGDSTR 672
            :||.....|:||:  |||::....:||                   .:.||.....|.|    ..
  Fly   815 VRSGAPGCTSSLT--TSPVKNHASSPL-------------------AQQLLEAASSAKN----DA 854

  Fly   673 RLIPLDQSLLSDEATESSNYDESLSTSNADEEVN------VVYRRILVPPTQPENTVERSKEDQK 731
            :::...:||||..|..:.......:|:.|..::|      .||.............:|||:....
  Fly   855 QILEKMKSLLSRYAAGNQTKAGVGATATAANKINSNGKKTPVYEDFTTAWVHSNGNLERSESCSP 919

  Fly   732 SPIVYNDFDRNVSPLGHNKSTHGKWKRRKGPAPAVPIPPR-KVLQRLPLQEIRHEFEI 788
            .....:......|....|.|..|........:.:|..|.| :.:.::| ..:||..|:
  Fly   920 PAKARSKRSSAASSCESNNSNAGAGSGAAAGSASVVSPRRERGMSKIP-APVRHHTEL 976

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MICAL-like	NP_648621.1	CH	14..111	CDD:278723
		LIM_like_1	146..207	CDD:188784
		DUF3585	778..933	CDD:288945	4/11 (36%)
pigs	NP_001245550.1	CH	22..159	CDD:237981
pigs	NP_001245550.1	GAS2	258..325	CDD:280367
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45452301
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930