Protein Alignment MICAL-like and Ehbp1

DIOPT Version :10

• Sequence 1: NP_648621.1
• Gene: MICAL-like / 39475
• FlyBaseID: FBgn0036333
• Length: 1010
• Species: Drosophila melanogaster
• Sequence 2: XP_011241983.1
• Gene: Ehbp1 / 216565
• MGIID: 2667252
• Length: 1257
• Species: Mus musculus
• Alignment Length: 1039
• Identity: 224/1039 - (21%)
• Similarity: 384/1039 - (36%)
• Gaps: 325/1039 - (31%)

  Fly    13 TKALEYWCRVVTQGYNGVKVENMTTSWRNGLAFCAIIHHFRPDLIDFDRLKADDIYENNDLAFTT 77
            :::|..|||.||:.|.|||:.|.||||||||:||||:|||||||||:..|...||.|||..|:..
Mouse   456 SQSLLAWCREVTKNYRGVKITNFTTSWRNGLSFCAILHHFRPDLIDYKSLNPQDIKENNKKAYDG 520

  Fly    78 AEKYLGIPALLDAADMVSYEVPDRLSILTYLSQF----------------------YKV------ 114
            ... :||..||:.:|||...:||:|:::|||.|.                      |||
Mouse   521 FAS-IGISRLLEPSDMVLLAIPDKLTVMTYLYQIRAHFSGQELNVVQIEENSSKSTYKVGNYETD 584

  Fly   115 LGKSLKHPKPEEPLGE---ESEPPQKVMHIVGMPRRDKCQKCNLPVFLAERVLVGKRAYHRTCLK 176
            ...|:...|....|.:   |.||.|.....|.:..:|.      .||:.:..:....:.|:
Mouse   585 TNSSVDQEKFYAELSDLKREPEPHQPARGAVDLLSQDD------SVFVTDSGVGESESEHQ---- 639

  Fly   177 CARCSSLLTPGSFYETEVNNIYCCETCPDEESEPESDILKLKTTTTDSPNDKQMVAQSSDYSEA- 240
                    ||.........:.|...|..|.|.: :|.....:|:.:|.|.    ::.|:|.::|
Mouse   640 --------TPDDHLSPSTASPYYRRTKSDTEPQ-KSQQSSARTSGSDDPG----LSSSTDSAQAL 691

  Fly   241 ------EDKQEDLEDNDIRTTDKPENFQPPSNKDEQNNELTINPVNPILSEERKISFI--PLDEE 297
                  ..|.|:||.:|:..:||        .||          |:|:.:.|:|:..:  ..|.|
Mouse   692 ASLGKKRLKAENLELSDLCVSDK--------KKD----------VSPLSAYEQKLQTVHASSDME 738

  Fly   298 DGGLIEQYNKSTTPVKPAIPEKPKVSTLPLDDEQHAGVEQNNDLAVSP-------ENDIPKEKLK 355
            .|.:.:..:............||.||:     ....|..::.|....|       |:|...:|..
Mouse   739 QGKMEKSRSLECRLDGELAITKPNVSS-----PSKLGYNRDTDFTKKPCASLRQIESDPDADKST 798

  Fly   356 ISSVSIYLEDDRLVVDAIHPDN------LDKQEALNNTSDALIPESQEAPIPENNTQVAIKPEDH 414
            ::             .|.||:.      |.:||.|...:..|:.:::.    :...:|..|....
Mouse   799 LN-------------HADHPNKAVQHRMLSRQEELKERARVLLEQARR----DAAFKVGSKHGGS 846

  Fly   415 ISPR--------------KENKIFS-NTESCSK--QEGVLPKQMDLESPKDKVIE----TKASET 458
            .:|.              |::.:|: ||....:  |:....::...|..:..:.|    .|.||.
Mouse   847 AAPALCSRQLNDVRNTGCKKHTVFTVNTAVMGRRGQQDEERRRQLRERARQLIAEARCGVKMSEL 911

  Fly   459 DYPEDLNPFKDDDSSKGANPFDSSDD-EVELLKAIPAQQSKGKVVPPRPPPPKIGLSSISNPSEK 522
            ....::...|..:.||.:.  |.:|: |::..:.||    :|.||........|. |.:.||.:
Mouse   912 PSYGEMAAEKLKERSKASG--DENDNIEIDTNEEIP----EGFVVGGGDELTNIE-SDLDNPEQ- 968

  Fly   523 PHSSPTLSHGKKMPMPTPRIS---ISKTQTPAKPMTHQGQKSSISSSSSEHLNSIRTFDRGADDR 584
             :|.......||:....|:::   .|..|......:.||:||.:....:|.|..       |.:|
Mouse   969 -NSKVVDLRLKKLLEAQPQVANLLPSAAQKAVTEASEQGEKSGVEDLRTERLQK-------ATER 1025

  Fly   585 GSSISLPSANGPRKPLRASVGSPLRSEESSPTTSLSSITS-----PMRKKRQAPLPPIQTDFDSD 644
            .           |.|:..:..|.:|.      |.|.|.:.     |..|::::    ||.|
Mouse  1026 F-----------RNPVVFNKDSTVRK------TQLQSFSQYVENRPEMKRQRS----IQED---- 1065

  Fly   645 PGFSKLSDEQKA-LLHTQLKAPNLGDSTRRLIPLDQSLLSDEATESSNYDESLSTSNADEEVNVV 708
               :|...|:|| :..||.|            |.:..:|:....::|.|
Mouse  1066 ---TKRGTEEKAEITETQRK------------PSEDEVLNKGFKDTSQY---------------- 1099

  Fly   709 YRRILVPPTQPENTVERSKEDQKSPIVYNDFDRNVSPLGHNKSTHGKWKRRKGPAPAVPIPPRKV 773
                                                                             
Mouse  1100 ----------------------------------------------------------------- 1099

  Fly   774 LQRLPLQEIRHEFEIIAVQQLGLEKQGVILEKMIRDRCERSLDATDTDGPESAEVLTNSKEVEDL 838
                    :..|...:..:|..::.:..::||.:|       ...||.        .|::|.|.:
Mouse  1100 --------VVGELAALENEQKQIDTRAALVEKRLR-------YLMDTG--------RNTEEEEAM 1141

  Fly   839 ILQLFELVNEKNELFRRQAELMYLRRQHRLEQEQADIEHEIRVLMGQPEHNKTDSDKAHEEVLIN 903
            :.:.|.|||:||.|.||..:|..|.::|.||:....:..|:|.::...:..||::.|..|::|::
Mouse  1142 MQEWFMLVNKKNALIRRMNQLSLLEKEHDLERRYELLNRELRAMLAIEDWQKTEAQKRREQLLLD 1206

  Fly   904 RLVKVVEMRNEVIDSLETDRVREAREDMSIKNRLHIYNSEREEPPAHPRSADKSSKKLSKKERK 967
            .||.:|:.|:.::..|:....:...||..::                 |:.:::..|::|||.|
Mouse  1207 ELVALVDKRDALVRDLDAQEKQAEEEDEHLE-----------------RTLEQNKGKMAKKEEK 1253

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MICAL-like	NP_648621.1	CH_MICALL2	11..115	CDD:409102	56/129 (43%)
		LIM_like_1	146..207	CDD:188784	9/60 (15%)
		PTZ00449	<411..727	CDD:185628	63/346 (18%)
		bMERB_dom	785..933	CDD:463467	38/147 (26%)
Ehbp1	XP_011241983.1	NT-C2	12..165	CDD:463058
		CH_EHBP1	454..560	CDD:409103	53/104 (51%)
		bMERB_dom	1103..1236	CDD:463467	38/147 (26%)