Protein Alignment MICAL-like and Ehbp1l1

DIOPT Version :10

• Sequence 1: NP_648621.1
• Gene: MICAL-like / 39475
• FlyBaseID: FBgn0036333
• Length: 1010
• Species: Drosophila melanogaster
• Sequence 2: XP_030106561.1
• Gene: Ehbp1l1 / 114601
• MGIID: 3612340
• Length: 1730
• Species: Mus musculus
• Alignment Length: 976
• Identity: 193/976 - (19%)
• Similarity: 277/976 - (28%)
• Gaps: 470/976 - (48%)

  Fly     3 DRR-------GTKVGTGTKALEYWCRVVTQGYNGVKVENMTTSWRNGLAFCAIIHHFRPDLIDFD 60
            |||       .|.|.:....|| ||:.||.||.||.:.|.|||||||||||||:|.|.||.||:.
Mouse  1209 DRRLPGSQAPPTLVSSSQSLLE-WCQEVTNGYRGVCITNFTTSWRNGLAFCAILHRFYPDKIDYF 1272

  Fly    61 RLKADDIYENNDLAFTTAEKYLGIPALLDAADMVSYEVPDRLSILTYLSQFYK-VLGKSLKHPKP 124
            .|...:|.:||..|| .....||:..||:.||||...|||:|.::|||.|... ..|:.|:..:.
Mouse  1273 SLDPLNIKQNNKQAF-DGFAALGVSRLLEPADMVLLSVPDKLIVMTYLCQIRAFCTGQELQLVQL 1336

  Fly   125 EEPLGEESEPPQKVMHIVGMPRRDKCQKCNLPVFLAERVLVGKRAYHRTCLKCARCSSLLTP-GS 188
            |...|.            |..|....|. :||                .||.....:..|.. |:
Mouse  1337 EGGGGS------------GTYRVGNAQP-SLP----------------DCLDAGDLAQRLREHGA 1372

  Fly   189 FYETEVNNIYCCETCPDEE-SEPESDILKLKTTTTDSPNDKQMVAQSSDYSEAEDKQEDLEDNDI 252
            ...||          |.|. :.....|.|:.:..||       ::.||...|||..||.:...
Mouse  1373 EVPTE----------PKEAVNRGTGAIPKVASRDTD-------LSCSSKDGEAEVAQEAIPQE-- 1418

  Fly   253 RTTDKPENFQPPSNKDEQNNELTINPVNPILSEERKISFIPLDEEDGGLIEQYNKSTTPVKPAIP 317
            ..||.|                                             :...|||||.||
Mouse  1419 APTDGP---------------------------------------------RARSSTTPVVPA-- 1436

  Fly   318 EKPKVSTLPLDDEQHAGVEQNNDLAVSPENDIPKEKLKISSVSIYLEDDRLVVDAIHPDNLDKQE 382
                           .|:..    .|.....:...:|:.|||:
Mouse  1437 ---------------EGLVN----GVGASGGVSGVRLRRSSVN---------------------- 1460

  Fly   383 ALNNTSDALIPESQEAPIPENNTQVAIKPEDHISPRKENKIFSNTESCSKQEGVLPKQMDLESPK 447
                        .:..|:|               |.:.:..||:.           :..||
Mouse  1461 ------------GEAGPVP---------------PPRAHGSFSHV-----------RDADL---- 1483

  Fly   448 DKVIETKASETDYPEDLNPFKDDDSSKGANPFDSSDDEVELLKAIPAQQSKGKVVPPRPPPPKIG 512
               ::.:.|..   .:.|.|..||...||           .:.|.||  ..|.|..|
Mouse  1484 ---LKKRRSRL---RNSNSFSVDDQDSGA-----------AVGAGPA--GPGAVEGP-------- 1521

  Fly   513 LSSISNPSEKPHSSPTLSHGKKMPMPTPRISISKTQTPAKPMTHQGQKSSISSSSSEHLNSIRTF 577
                 ||:..|.::|       :|.|.|:      |.|
Mouse  1522 -----NPASSPDANP-------LPAPAPQ------QPP--------------------------- 1541

  Fly   578 DRGADDRGSSISLPSANGPRKPLRASVGSPLRSEESSPTTSLSSITSPMRKKRQAPLPPIQTDFD 642
                                       |.|..:||||
Mouse  1542 ---------------------------GGPPPTEESS---------------------------- 1551

  Fly   643 SDPGFSKLSDEQKALLHTQLKAPNLGDSTRRLIPLDQSLLSDEATESSNYDESLSTSNADEEVNV 707
                                  |:||:.|.
Mouse  1552 ----------------------PSLGEETG----------------------------------- 1559

  Fly   708 VYRRILVPPTQPENTVERSKEDQKSPIVYNDFDRNVSPLGHNKSTHGKWKRRKGPAPAVPIPPRK 772
                                                                             
Mouse  1560 ----------------------------------------------------------------- 1559

  Fly   773 VLQRL--PLQEIRHEFEIIAVQQLGLEKQGVILEKMIRDRCERSLDATDTDGPESAEVLTNSKEV 835
             |||.  ..|.:..|.:.:..:|..::.:...:||.:|...|..               .|..:.
Mouse  1560 -LQRFQDTSQYVCAELQALEQEQGQIDGRAAEVEKQLRSLMESG---------------ANRLQE 1608

  Fly   836 EDLILQLFELVNEKNELFRRQAELMYLRRQHRLEQEQADIEHEIRVLMGQPEHNKTDSDKAHEEV 900
            |.||.:.|.|||:||.|.|||.:|..|..:..||:....:..|:|.::...|..||.:.:..|::
Mouse  1609 EVLIQEWFTLVNKKNALIRRQDQLQLLIEEQDLERRFELLSRELRAMLAIEEWQKTVAQQHREQL 1673

  Fly   901 LINRLVKVVEMRNEVIDSLETDRVREAREDMSIKNRLHIYNSEREEPPAHPRSADKSSKKLSKKE 965
            |:..||.:|..|:|::            .|:..|.|:.:...||.|.....|.. |.|::||::|
Mouse  1674 LLEELVSLVNQRDELV------------RDLDQKERIALEEDERLERGLEQRRR-KVSRQLSRRE 1725

  Fly   966 R 966
            |
Mouse  1726 R 1726

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MICAL-like	NP_648621.1	CH_MICALL2	11..115	CDD:409102	52/104 (50%)
		LIM_like_1	146..207	CDD:188784	11/61 (18%)
		PTZ00449	<411..727	CDD:185628	37/315 (12%)
		bMERB_dom	785..933	CDD:463467	37/147 (25%)
Ehbp1l1	XP_030106561.1	NT-C2	12..164	CDD:463058
		PHA03307	185..>538	CDD:223039
		CH_EHBP1L1	1223..1327	CDD:409104	52/105 (50%)
		bMERB_dom	1573..1706	CDD:463467	40/159 (25%)