Protein Alignment CG10749 and LDHAL6B

DIOPT Version :10

• Sequence 1: NP_648616.1
• Gene: CG10749 / 39470
• FlyBaseID: FBgn0036328
• Length: 347
• Species: Drosophila melanogaster
• Sequence 2: NP_149972.1
• Gene: LDHAL6B / 92483
• HGNCID: 21481
• Length: 381
• Species: Homo sapiens
• Alignment Length: 307
• Identity: 73/307 - (23%)
• Similarity: 134/307 - (43%)
• Gaps: 59/307 - (19%)

  Fly    29 KVAVVGSVGGIGQ--PLSLLLKH-NPQISTLSLYDIKNTTGVGVDLSHINTRASVCPFEGKNGLK 90
            ||:::|: |.:|.  .:|:|||. :.:::.:.| |.....|..:||.|.:      ||.....:.
Human    71 KVSIIGT-GSVGMACAISILLKGLSDELALVDL-DEDKLKGETMDLQHGS------PFTKMPNIV 127

  Fly    91 KAMD-----KADIVVIPAGLPRKPGMKREDLVDVNASVACEVAFAASEVCPGAMLAFITNPINVI 150
            .:.|     .:::|:|.||..::.|..|.:||..|.::...:..:..:..|...|..::||::::
Human   128 CSKDYFVTANSNLVIITAGARQEKGETRLNLVQRNVAIFKLMISSIVQYSPHCKLIIVSNPVDIL 192

  Fly   151 VPIVATILKAKGTYDPNRLFGV-TTLDVVRAQTFVADILNVDPQKVNIPVIGGHTGRTILPILSQ 214
            . .||..|.|   :..||:.|. ..||..|.:..:...|.:..:..:..::|.| |.:.:|:.|.
Human   193 T-YVAWKLSA---FPKNRIIGSGCNLDTARFRFLIGQKLGIHSESCHGWILGEH-GDSSVPVWSG 252

  Fly   215 CD---PPFK------GTDKEREA---LIQRIQNAGTEVVNAKD------GLGSATLSMAFAAT-- 259
            .:   .|.|      ||||:.|.   :.:.:.....|::..|.      ||..|.|:.:....
Human   253 VNIAGVPLKDLNSDIGTDKDPEQWKNVHKEVTATAYEIIKMKGYTSWAIGLSVADLTESILKNLR 317

  Fly   260 --QFVSSLIKGIKGSKDECIVECAYVESDVTEAQFFATPLILGPQGV 304
              ..||::|||:.|               :.|..|.:.|.|||..|:
Human   318 RIHPVSTIIKGLYG---------------IDEEVFLSIPCILGENGI 349

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10749	NP_648616.1	MDH_glyoxysomal_mitochondrial	28..337	CDD:133422	73/307 (24%)
LDHAL6B	NP_149972.1	LDH_1	68..376	CDD:133429	73/307 (24%)