Protein Alignment CG10749 and MDH3

DIOPT Version :9

• Sequence 1: NP_648616.1
• Gene: CG10749 / 39470
• FlyBaseID: FBgn0036328
• Length: 347
• Species: Drosophila melanogaster
• Sequence 2: NP_010205.1
• Gene: MDH3 / 851481
• SGDID: S000002236
• Length: 343
• Species: Saccharomyces cerevisiae
• Alignment Length: 337
• Identity: 127/337 - (37%)
• Similarity: 192/337 - (56%)
• Gaps: 34/337 - (10%)

  Fly    28 LKVAVVGSVGGIGQPLSLLLKHNPQISTLSLYDIKNTTGVGVDLSHINTRASVCPFEGKNGLKKA 92
            :|||::|:.||:|||||||||.:|.:|.|:||||:...|:|.|||||||.:| |....|:.::..
Yeast     2 VKVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSHINTNSS-CVGYDKDSIENT 65

  Fly    93 MDKADIVVIPAGLPRKPGMKREDLVDVNASVACEVAFAASEVCPGAMLAFITNPINVIVPIVATI 157
            :..|.:|:||||:|||||:.|:||..:||.:...:..|..:..|.|.:..|:||:|.:|||....
Yeast    66 LSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNPVNSLVPIAVET 130

  Fly   158 LKAKGTYDPNRLFGVTTLDVVRAQTFVADILNVDPQKV-----------NIPVIGGHTGRTILPI 211
            ||..|.:.|..:.|||.||:|||:||:.|.|.:...|:           .:.|||||:|.||:||
Yeast   131 LKKMGKFKPGNVMGVTNLDLVRAETFLVDYLMLKNPKIGQEQDKTTMHRKVTVIGGHSGETIIPI 195

  Fly   212 LSQCDPPFKGTDKEREALIQRIQNAGTEVVNAKDGLGSATLSMAFAATQFVSSLIKGIKGSKDEC 276
            ::.....|: .||:.|..|.|:|..|.|:|.||.|.||||||||||..:|...:::.....|.|.
Yeast   196 ITDKSLVFQ-LDKQYEHFIHRVQFGGDEIVKAKQGAGSATLSMAFAGAKFAEEVLRSFHNEKPET 259

  Fly   277 IVECAYV----------------ESDVTEAQFFATPLILGPQGVK--ENTGLPDLDDEERKALNG 323
            ....|:|                ::.:   ::|:.|::|....|.  :.:.|..|...|.:.:|.
Yeast   260 ESLSAFVYLPGLKNGKKAQQLVGDNSI---EYFSLPIVLRNGSVVSIDTSVLEKLSPREEQLVNT 321

  Fly   324 MLPILKESIAKG 335
            .:..|:::|.||
Yeast   322 AVKELRKNIEKG 333

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10749	NP_648616.1	MDH_glyoxysomal_mitochondrial	28..337	CDD:133422	127/337 (38%)
		MDH_euk_gproteo	29..345	CDD:130833	127/336 (38%)
MDH3	NP_010205.1	MDH_euk_gproteo	3..339	CDD:130833	127/336 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0039
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG56560
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11540
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1106
TreeFam	1	0.960	-	-
	6	5.880