DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10749 and MDH

DIOPT Version :9

Sequence 1:	NP_648616.1	Gene:	CG10749 / 39470	FlyBaseID:	FBgn0036328	Length:	347	Species:	Drosophila melanogaster
Sequence 2:	NP_190336.1	Gene:	MDH / 823906	AraportID:	AT3G47520	Length:	403	Species:	Arabidopsis thaliana

Alignment Length:	315	Identity:	162/315 - (51%)
Similarity:	214/315 - (67%)	Gaps:	4/315 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 INRGLKVAVVGSVGGIGQPLSLLLKHNPQISTLSLYDIKNTTGVGVDLSHINTRASVCPFEGKNG 88
            ||...||||:|:.||||||||||:|.:|.:|||.||||.|..||..||||.||.:.|..|.|.:.
plant    79 INASYKVAVLGAAGGIGQPLSLLIKMSPLVSTLHLYDIANVKGVAADLSHCNTPSQVRDFTGPSE 143

  Fly    89 LKKAMDKADIVVIPAGLPRKPGMKREDLVDVNASVACEVAFAASEVCPGAMLAFITNPINVIVPI 153
            |...:...::||||||:||||||.|:||.::||::...:..|.:|.||.|.:..|:||:|..|||
plant   144 LADCLKDVNVVVIPAGVPRKPGMTRDDLFNINANIVKTLVEAVAENCPNAFIHIISNPVNSTVPI 208

  Fly   154 VATILKAKGTYDPNRLFGVTTLDVVRAQTFVADILNVDPQKVNIPVIGGHTGRTILPILSQCDPP 218
            .|.:||.||.|||.:||||||||||||.|||:...|:....|::||||||.|.||||:||:..|.
plant   209 AAEVLKKKGVYDPKKLFGVTTLDVVRANTFVSQKKNLKLIDVDVPVIGGHAGITILPLLSKTKPS 273

  Fly   219 FKGTDKEREALIQRIQNAGTEVVNAKDGLGSATLSMAFAATQFVSSLIKGIKGSKDECIVECAYV 283
            ...||:|.:.|..||||||||||:||.|.||||||||:||.:||.|.::.:.|..|  :.||::|
plant   274 VNFTDEEIQELTVRIQNAGTEVVDAKAGAGSATLSMAYAAARFVESSLRALDGDGD--VYECSFV 336

  Fly   284 ESDVTEAQFFATPLILGPQGVKE--NTGLPDLDDEERKALNGMLPILKESIAKGI 336
            ||.:|:..|||:.:.:|..|::.  .:.|..|.:.|:|||..:...||.||.||:
plant   337 ESTLTDLPFFASRVKIGKNGLEAVIESDLQGLTEYEQKALEALKVELKASIDKGV 391

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10749	NP_648616.1	MDH_glyoxysomal_mitochondrial	28..337	CDD:133422	160/311 (51%)
CG10749	NP_648616.1	MDH_euk_gproteo	29..345	CDD:130833	160/310 (52%)
MDH	NP_190336.1	PLN00106	80..389	CDD:215058	159/310 (51%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0039
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG56560
OrthoDB	1	1.010	-	-		D976445at2759
OrthoFinder	1	1.000	-	-		FOG0001716
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11540
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1106
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	8	7.890