DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10749 and mMDH2

DIOPT Version :9

Sequence 1:	NP_648616.1	Gene:	CG10749 / 39470	FlyBaseID:	FBgn0036328	Length:	347	Species:	Drosophila melanogaster
Sequence 2:	NP_188120.1	Gene:	mMDH2 / 820731	AraportID:	AT3G15020	Length:	341	Species:	Arabidopsis thaliana

Alignment Length:	324	Identity:	162/324 - (50%)
Similarity:	217/324 - (66%)	Gaps:	10/324 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 GYINRGL--------KVAVVGSVGGIGQPLSLLLKHNPQISTLSLYDIKNTTGVGVDLSHINTRA 78
            |.:.||.        ||.::|:.||||||||||:|.||.:|:||||||.||.||..|:.|||||:
plant    16 GLLRRGFASESVPDRKVVILGAAGGIGQPLSLLMKLNPLVSSLSLYDIANTPGVAADVGHINTRS 80

  Fly    79 SVCPFEGKNGLKKAMDKADIVVIPAGLPRKPGMKREDLVDVNASVACEVAFAASEVCPGAMLAFI 143
            .|..:.|.:.|.||::.||:|:||||:||||||.|:||.::||.:...::.|.::.||.|::..|
plant    81 QVSGYMGDDDLGKALEGADLVIIPAGVPRKPGMTRDDLFNINAGIVKNLSIAIAKYCPQALVNMI 145

  Fly   144 TNPINVIVPIVATILKAKGTYDPNRLFGVTTLDVVRAQTFVADILNVDPQKVNIPVIGGHTGRTI 208
            :||:|..|||.|.|.|..||||..:||||||||||||:||.|...:|:..:||:||:|||.|.||
plant   146 SNPVNSTVPIAAEIFKKAGTYDEKKLFGVTTLDVVRARTFYAGKSDVNVAEVNVPVVGGHAGITI 210

  Fly   209 LPILSQCDPPFKGTDKEREALIQRIQNAGTEVVNAKDGLGSATLSMAFAATQFVSSLIKGIKGSK 273
            ||:.||..|....:|....||.:|.|:.|||||.||.|.||||||||:|...|..:.:||:.|..
plant   211 LPLFSQASPQANLSDDLIRALTKRTQDGGTEVVEAKAGKGSATLSMAYAGALFADACLKGLNGVP 275

  Fly   274 DECIVECAYVESDVTEAQFFATPLILGPQGVKENTGLPDLDDEERKALNGMLPILKESIAKGIK 337
            :  :|||::|:|.:||..|||:.:.||..||:|...|..|.|.|::.|..:...||.||.||||
plant   276 N--VVECSFVQSTITELPFFASKVRLGKNGVEEVLDLGPLSDFEKEGLEALKAELKSSIEKGIK 337

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10749	NP_648616.1	MDH_glyoxysomal_mitochondrial	28..337	CDD:133422	157/316 (50%)
CG10749	NP_648616.1	MDH_euk_gproteo	29..345	CDD:130833	159/309 (51%)
mMDH2	NP_188120.1	PLN00106	14..334	CDD:215058	158/319 (50%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0039
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG56560
OrthoDB	1	1.010	-	-		D976445at2759
OrthoFinder	1	1.000	-	-		FOG0001716
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11540
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1106
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	8	7.890