DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10749 and PMDH1

DIOPT Version :9

Sequence 1:	NP_648616.1	Gene:	CG10749 / 39470	FlyBaseID:	FBgn0036328	Length:	347	Species:	Drosophila melanogaster
Sequence 2:	NP_179863.1	Gene:	PMDH1 / 816808	AraportID:	AT2G22780	Length:	354	Species:	Arabidopsis thaliana

Alignment Length:	344	Identity:	166/344 - (48%)
Similarity:	229/344 - (66%)	Gaps:	14/344 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 SRLLSHVG--NLPPKVQQLGYINR----------GLKVAVVGSVGGIGQPLSLLLKHNPQISTLS 57
            :|:.:|:.  ||..::.....:||          |.|||::|:.|||||||::|:|.||.:|.|.
plant     8 ARISAHLNPPNLHNQIADGSGLNRVACRAKGGSPGFKVAILGAAGGIGQPLAMLMKMNPLVSVLH 72

  Fly    58 LYDIKNTTGVGVDLSHINTRASVCPFEGKNGLKKAMDKADIVVIPAGLPRKPGMKREDLVDVNAS 122
            |||:.|..||..|:||::|.|.|..|.|:..|::|:...|:|:||||:||||||.|:||.::||.
plant    73 LYDVANAPGVTADISHMDTSAVVRGFLGQPQLEEALTGMDLVIIPAGVPRKPGMTRDDLFNINAG 137

  Fly   123 VACEVAFAASEVCPGAMLAFITNPINVIVPIVATILKAKGTYDPNRLFGVTTLDVVRAQTFVADI 187
            :...::.|.::.||.|::..|:||:|..|||.|.:.|..||:||.:|.|||.||||||.||||::
plant   138 IVRTLSEAIAKCCPKAIVNIISNPVNSTVPIAAEVFKKAGTFDPKKLMGVTMLDVVRANTFVAEV 202

  Fly   188 LNVDPQKVNIPVIGGHTGRTILPILSQCDPPFKGTDKEREALIQRIQNAGTEVVNAKDGLGSATL 252
            :::||::|.:||:|||.|.||||:|||..||...|.||.|.|..||||.|||||.||.|.|||||
plant   203 MSLDPREVEVPVVGGHAGVTILPLLSQVKPPCSFTQKEIEYLTDRIQNGGTEVVEAKAGAGSATL 267

  Fly   253 SMAFAATQFVSSLIKGIKGSKDECIVECAYVESDVTEAQFFATPLILGPQGVKENTGLPDLDDEE 317
            |||:||.:|..:.::|::|  |..|||||||.|.|||..|||:.:.||..|:.|..||..|::.|
plant   268 SMAYAAVEFADACLRGLRG--DANIVECAYVASHVTELPFFASKVRLGRCGIDEVYGLGPLNEYE 330

  Fly   318 RKALNGMLPILKESIAKGI 336
            |..|......|..||.||:
plant   331 RMGLEKAKKELSVSIHKGV 349

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10749	NP_648616.1	MDH_glyoxysomal_mitochondrial	28..337	CDD:133422	159/309 (51%)
CG10749	NP_648616.1	MDH_euk_gproteo	29..345	CDD:130833	159/308 (52%)
PMDH1	NP_179863.1	PLN00106	33..347	CDD:215058	158/315 (50%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0039
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG56560
OrthoDB	1	1.010	-	-		D976445at2759
OrthoFinder	1	1.000	-	-		FOG0001716
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11540
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1106
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	8	7.890