DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10749 and uevld

DIOPT Version :9

Sequence 1:	NP_648616.1	Gene:	CG10749 / 39470	FlyBaseID:	FBgn0036328	Length:	347	Species:	Drosophila melanogaster
Sequence 2:	NP_001003619.1	Gene:	uevld / 445225	ZFINID:	ZDB-GENE-040801-138	Length:	471	Species:	Danio rerio

Alignment Length:	382	Identity:	84/382 - (21%)
Similarity:	141/382 - (36%)	Gaps:	117/382 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 SRLLSHVGNLPPKVQQLGYINRG-------LKVAVVGSVG-GIGQPLSLLLKHNPQISTLSLYDI 61
            |.||.:|.||.        |..|       :||:|:|... ||...||::.|  ..:..|.|.||
Zfish   153 SNLLDYVSNLT--------ITEGGNRPDQEVKVSVIGGGDLGIAAVLSIMAK--SCVDKLVLIDI 207

  Fly    62 --KNTTGVGVDLSHINTRASVCPFEGKNGLKKAMDKADIVVIPAGLPRKPGMKRE----DLVDVN 120
              .:|.|..:||...    |:...|....| .|...:.::||.|.     ....|    .:|..|
Zfish   208 PENSTKGGTMDLEIF----SLPKVEVSKDL-SASAGSKVLVITAN-----AWSDEQSYLSVVQTN 262

  Fly   121 ASVACEVAFAASEVCPGAMLAFITNPINVIVPIV---ATILKAKGTYDPNRLFGVTTLDVVRAQT 182
            ..:...:....:::.|.|:|...:.|::|:..:.   :.:|       |.::.||.
Zfish   263 VDMYRGIIPRLAQLSPNAVLVIASQPVDVMTHVAWRQSHLL-------PTQVIGVG--------- 311

  Fly   183 FVADILNVDPQK----VNIPVIGGHTGRTILPILSQCDPPFKGTDKEREALIQRIQNAGTEVVNA 243
                 .|:|.|:    :||.::..:||:....|         |...|.:..:......||:.:.|
Zfish   312 -----CNLDSQRLSHIINISLVANNTGKQAWVI---------GELSENKVAVWGNMGPGTDQLQA 362

  Fly   244 KDGLGSAT---LSMAFAATQFVSSLIKGIKGSKD------------ECIVECAYVESDVTEAQ-- 291
            ...:.::|   :..||       .:||| :|.:.            ..:.....|.|..|.|:
Zfish   363 LTPVSNSTKPLMDRAF-------EMIKG-RGQRSWSVGLSIADITHSIVTNQKKVHSVTTLAEGW 419

  Fly   292 -------FFATPLILGPQGVKENTGLPDL---DDEERKALNGMLPILKESIAKGIKL 338
                   |.:.|.|||..|   :|.||.:   .::|.|        |:||:|..:.|
Zfish   420 GGIGSKVFLSLPCILGETG---STRLPGVALGSEDEMK--------LRESVACQVNL 465

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10749	NP_648616.1	MDH_glyoxysomal_mitochondrial	28..337	CDD:133422	75/349 (21%)
CG10749	NP_648616.1	MDH_euk_gproteo	29..345	CDD:130833	76/351 (22%)
uevld	NP_001003619.1	UEV	21..139	CDD:283415
		LDH_1	172..468	CDD:133429	76/355 (21%)
		L-LDH-NAD	179..460	CDD:273796	72/341 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0039
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810