Protein Alignment CG10749 and LDHC

DIOPT Version :9

• Sequence 1: NP_648616.1
• Gene: CG10749 / 39470
• FlyBaseID: FBgn0036328
• Length: 347
• Species: Drosophila melanogaster
• Sequence 2: NP_002292.1
• Gene: LDHC / 3948
• HGNCID: 6544
• Length: 332
• Species: Homo sapiens
• Alignment Length: 341
• Identity: 81/341 - (23%)
• Similarity: 144/341 - (42%)
• Gaps: 60/341 - (17%)

  Fly    25 NRGLKVAVVGSVGGIGQ--PLSLLLKHNPQISTLSLYDI--KNTTGVGVDLSHINTRASVCPF-E 84
            |...|:.:||: |.:|.  .:|:|||  .....|:|.|:  ....|..:||.|.:...|.... .
Human    18 NSQCKITIVGT-GAVGMACAISILLK--DLADELALVDVALDKLKGEMMDLQHGSLFFSTSKITS 79

  Fly    85 GKNGLKKAMDKADIVVIPAGLPRKPGMKREDLVDVNASVACEVAFAASEVCPGAMLAFITNPINV 149
            ||:....|..:  ||::.||..::.|..|..||..|.::...:..|.....|...:..::||:::
Human    80 GKDYSVSANSR--IVIVTAGARQQEGETRLALVQRNVAIMKSIIPAIVHYSPDCKILVVSNPVDI 142

  Fly   150 IVPIVATILKAKGTYDPNRLFGV-TTLDVVRAQTFVADILNVDPQKVNIPVIGGHTGRTILPI-- 211
            :..||..|.....|    |:.|. ..||..|.:..:.:.|.|.|...:..:||.| |.:.:|:
Human   143 LTYIVWKISGLPVT----RVIGSGCNLDSARFRYLIGEKLGVHPTSCHGWIIGEH-GDSSVPLWS 202

  Fly   212 --------LSQCDPPFKGTDKERE---ALIQRIQNAGTEVVNAKD----GLGSATLSMA------ 255
                    |...||.. |||.::|   .:.:::..:..|::..|.    .:|.:.:.:.
Human   203 GVNVAGVALKTLDPKL-GTDSDKEHWKNIHKQVIQSAYEIIKLKGYTSWAIGLSVMDLVGSILKN 266

  Fly   256 FAATQFVSSLIKGIKGSKDECIVECAYVESDVTEAQFFATPLILGPQGVKENTGLPDLDDEE--- 317
            ......||:::||:.|.|:|.               |.:.|.:||..||.:...: :|:.||
Human   267 LRRVHPVSTMVKGLYGIKEEL---------------FLSIPCVLGRNGVSDVVKI-NLNSEEEAL 315

  Fly   318 -RKALNGMLPILKESI 332
             :|:...:..|.|:.|
Human   316 FKKSAETLWNIQKDLI 331

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10749	NP_648616.1	MDH_glyoxysomal_mitochondrial	28..337	CDD:133422	80/338 (24%)
		MDH_euk_gproteo	29..345	CDD:130833	80/337 (24%)
LDHC	NP_002292.1	LDH_1	18..329	CDD:133429	79/337 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0039
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810