Protein Alignment CG10749 and LDHB

DIOPT Version :9

• Sequence 1: NP_648616.1
• Gene: CG10749 / 39470
• FlyBaseID: FBgn0036328
• Length: 347
• Species: Drosophila melanogaster
• Sequence 2: XP_006719137.1
• Gene: LDHB / 3945
• HGNCID: 6541
• Length: 353
• Species: Homo sapiens
• Alignment Length: 273
• Identity: 57/273 - (20%)
• Similarity: 107/273 - (39%)
• Gaps: 59/273 - (21%)

  Fly    29 KVAVVGSVGGIGQPLSLLLKHNPQISTLSLYDI--KNTTGVGVDLSHINTRASVCPFEGKNGLKK 91
            |:.||| ||.:|...::.:........|:|.|:  ....|..:||.|           |...|:.
Human    23 KITVVG-VGQVGMACAISILGKSLADELALVDVLEDKLKGEMMDLQH-----------GSLFLQT 75

  Fly    92 AMDKAD----------IVVIPAGLPRKPGMKREDLVDVNASVACEVAFAASEVCPGAMLAFITNP 146
            ....||          |||:.||:.::.|..|.:||..|.:|...:.....:..|..::..::||
Human    76 PKIVADKDYSVTANSKIVVVTAGVRQQEGESRLNLVQRNVNVFKFIIPQIVKYSPDCIIIVVSNP 140

  Fly   147 INVIVPIVATILKAKGTYDPNRLFGV---------TTLDVVRAQTFVADILNVDPQKVNIPVIGG 202
            ::::            ||...:|.|:         ..||..|.:..:|:.|.:.|...:..::|.
Human   141 VDIL------------TYVTWKLSGLPKHRVIGSGCNLDSARFRYLMAEKLGIHPSSCHGWILGE 193

  Fly   203 H--------TGRTILPILSQCDPPFKGTDKERE---ALIQRIQNAGTEVVNAKDGLGSATLSMAF 256
            |        :|..:..:..|...|..|||.:.|   .:.:.:..:..||:..|   |....::..
Human   194 HGDSSVAVWSGVNVAGVSLQELNPEMGTDNDSENWKEVHKMVVESAYEVIKLK---GYTNWAIGL 255

  Fly   257 AATQFVSSLIKGI 269
            :....:.|::|.:
Human   256 SVADLIESMLKNL 268

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10749	NP_648616.1	MDH_glyoxysomal_mitochondrial	28..337	CDD:133422	57/273 (21%)
		MDH_euk_gproteo	29..345	CDD:130833	57/273 (21%)
LDHB	XP_006719137.1	LDH_1	20..279	CDD:133429	57/273 (21%)
		L-LDH-NAD	26..279	CDD:273796	56/270 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0039
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810