Protein Alignment CG10749 and LDHA

DIOPT Version :9

• Sequence 1: NP_648616.1
• Gene: CG10749 / 39470
• FlyBaseID: FBgn0036328
• Length: 347
• Species: Drosophila melanogaster
• Sequence 2: NP_001158886.1
• Gene: LDHA / 3939
• HGNCID: 6535
• Length: 361
• Species: Homo sapiens
• Alignment Length: 334
• Identity: 83/334 - (24%)
• Similarity: 143/334 - (42%)
• Gaps: 58/334 - (17%)

  Fly    29 KVAVVGSVGGIGQPLSLLLKHNPQISTLSLYDI--KNTTGVGVDLSH----INTRASVCPFEGKN 87
            |:.||| ||.:|...::.:........|:|.|:  ....|..:||.|    :.|...|   .||:
Human    51 KITVVG-VGAVGMACAISILMKDLADELALVDVIEDKLKGEMMDLQHGSLFLRTPKIV---SGKD 111

  Fly    88 GLKKAMDKADIVVIPAGLPRKPGMKREDLVDVNASVACEVAFAASEVCPGAMLAFITNPINVIVP 152
            ....|..|  :|:|.||..::.|..|.:||..|.::...:.....:..|...|..::||::::..
Human   112 YNVTANSK--LVIITAGARQQEGESRLNLVQRNVNIFKFIIPNVVKYSPNCKLLIVSNPVDILTY 174

  Fly   153 IVATILKAKGTYDPNRLFGV-TTLDVVRAQTFVADILNVDPQKVNIPVIGGHTGRTILPILSQCD 216
            :.   .|..| :..||:.|. ..||..|.:..:.:.|.|.|...:..|:|.| |.:.:|:.|..:
Human   175 VA---WKISG-FPKNRVIGSGCNLDSARFRYLMGERLGVHPLSCHGWVLGEH-GDSSVPVWSGMN 234

  Fly   217 ---------PPFKGTDKERE---ALIQRIQNAGTEVVNAKD------GLGSATLSMA----FAAT 259
                     .|..||||::|   .:.:::..:..||:..|.      ||..|.|:.:    ....
Human   235 VAGVSLKTLHPDLGTDKDKEQWKEVHKQVVESAYEVIKLKGYTSWAIGLSVADLAESIMKNLRRV 299

  Fly   260 QFVSSLIKGIKGSKDECIVECAYVESDVTEAQFFATPLILGPQGVKENTGLPDLDDEE---RKAL 321
            ..||::|||:.|.||:.               |.:.|.|||..|:.:...:....:||   :|:.
Human   300 HPVSTMIKGLYGIKDDV---------------FLSVPCILGQNGISDLVKVTLTSEEEARLKKSA 349

  Fly   322 NGMLPILKE 330
            :.:..|.||
Human   350 DTLWGIQKE 358

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10749	NP_648616.1	MDH_glyoxysomal_mitochondrial	28..337	CDD:133422	83/334 (25%)
		MDH_euk_gproteo	29..345	CDD:130833	83/334 (25%)
LDHA	NP_001158886.1	LDH_1	48..358	CDD:133429	81/332 (24%)
		L-LDH-NAD	54..353	CDD:273796	79/324 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0039
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810