Protein Alignment CG10749 and Mdh1

DIOPT Version :10

• Sequence 1: NP_648616.1
• Gene: CG10749 / 39470
• FlyBaseID: FBgn0036328
• Length: 347
• Species: Drosophila melanogaster
• Sequence 2: NP_001303604.1
• Gene: Mdh1 / 17449
• MGIID: 97051
• Length: 355
• Species: Mus musculus
• Alignment Length: 336
• Identity: 77/336 - (22%)
• Similarity: 128/336 - (38%)
• Gaps: 67/336 - (19%)

  Fly    28 LKVAVVGSVGGIGQPLSLLLKHNPQISTLSLYDIKNTTGVGVDLSHINTRASVCPFEG-KNGLKK 91
            ::|.|.|:.|              ||:...||.|.|.:..|.|...|.....:.|..| .:|:..
Mouse     5 IRVLVTGAAG--------------QIAYSLLYSIGNGSVFGKDQPIILVLLDITPMMGVLDGVLM 55

  Fly    92 --------------AMDK-------ADIVVIPAGLPRKPGMKREDLVDVNASVACEVAFAASEVC 135
                          |.||       .|:.|:...:||:.||:|:||:..|..:......|..:..
Mouse    56 ELQDCALPLLQDVIATDKEEIAFKDLDVAVLVGSMPRREGMERKDLLKANVKIFKSQGTALEKYA 120

  Fly   136 PGAMLAFIT-NPINVIVPIVATILKAKGTYDPNRLFGVTTLDVVRAQTFVADILNVDPQKVNIPV 199
            ..::...:. ||.|.   ...|..|:..:........:|.||..||::.:|..|.|....|...:
Mouse   121 KKSVKVIVVGNPANT---NCLTASKSAPSIPKENFSCLTRLDHNRAKSQIALKLGVTADDVKNVI 182

  Fly   200 IGGHTGRTILPILSQCDPPFKGTDKE---REAL----------IQRIQNAGTEVVNAKDGLGSAT 251
            |.|:...|..|.::......:|  ||   .|||          |..:|..|..|:.|:      .
Mouse   183 IWGNHSSTQYPDVNHAKVKLQG--KEVGVYEALKDDSWLKGEFITTVQQRGAAVIKAR------K 239

  Fly   252 LSMAFAATQFVSSLIKGIKGSKDECIVECAYVESD-----VTEAQFFATPLILGPQGVKENTGLP 311
            ||.|.:|.:.::..|:.|.....|.......|.||     |.:...::.|:::..:..|...|||
Mouse   240 LSSAMSAAKAIADHIRDIWFGTPEGEFVSMGVISDGNSYGVPDDLLYSFPVVIKNKTWKFVEGLP 304

  Fly   312 DLDDEERKALN 322
             ::|..|:.::
Mouse   305 -INDFSREKMD 314

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10749	NP_648616.1	MDH_glyoxysomal_mitochondrial	28..337	CDD:133422	77/336 (23%)
Mdh1	NP_001303604.1	MDH_cytoplasmic_cytosolic	3..328	CDD:133421	77/336 (23%)
		PTS1	353..355