Protein Alignment CG10748 and LDHAL6B

DIOPT Version :9

• Sequence 1: NP_648615.1
• Gene: CG10748 / 39469
• FlyBaseID: FBgn0036327
• Length: 349
• Species: Drosophila melanogaster
• Sequence 2: NP_149972.1
• Gene: LDHAL6B / 92483
• HGNCID: 21481
• Length: 381
• Species: Homo sapiens
• Alignment Length: 333
• Identity: 82/333 - (24%)
• Similarity: 147/333 - (44%)
• Gaps: 58/333 - (17%)

  Fly    24 KVAVVGAGG-GIGQPLSLLLRRCPGI-DELALHDLSE--MKGIATDLSHISQTGKVIGFTGEKEL 84
            ||:::|.|. |:...:|:||:   |: |||||.||.|  :||...||.|.|...|:......|:.
Human    71 KVSIIGTGSVGMACAISILLK---GLSDELALVDLDEDKLKGETMDLQHGSPFTKMPNIVCSKDY 132

  Fly    85 ESAVSGADVVVVAAGMPRLPGMQRDHLMAANGNVAVKVATAISNASPRAHLAFITNPVNMIVPAA 149
             ...:.:::|::.||..:..|..|.:|:..|..:...:.::|...||...|..::|||:::...|
Human   133 -FVTANSNLVIITAGARQEKGETRLNLVQRNVAIFKLMISSIVQYSPHCKLIIVSNPVDILTYVA 196

  Fly   150 AEVLMAHGTFDSRRLFGI-TTLDVVRSKKFIGDSMNISPD-----------DVNIPVIGG--HAG 200
            .::    ..|...|:.|. ..||..|.:..||..:.|..:           |.::||..|  .||
Human   197 WKL----SAFPKNRIIGSGCNLDTARFRFLIGQKLGIHSESCHGWILGEHGDSSVPVWSGVNIAG 257

  Fly   201 ITILPLISQCQPIYRCDLQEIQNLTHRIQEAGTEVVNAKAGKGSATLSMAYAGATF--------- 256
            :.:..|.|....  ..|.::.:|:...:.....|::..| |..|..:.::.|..|.
Human   258 VPLKDLNSDIGT--DKDPEQWKNVHKEVTATAYEIIKMK-GYTSWAIGLSVADLTESILKNLRRI 319

  Fly   257 --VNSLLRGIAGQDGLIECAFVASKLTDAPFFASPLELGKDGIKRYIPL---PQMSDYEKEALEK 316
              |:::::|:.|.|             :..|.:.|..||::||...|.:   |:...:.|::.:.
Human   320 HPVSTIIKGLYGID-------------EEVFLSIPCILGENGITNLIKIKLTPEEEAHLKKSAKT 371

  Fly   317 LLPILRQN 324
            |..|  ||
Human   372 LWEI--QN 377

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10748	NP_648615.1	MDH_euk_gproteo	36..333	CDD:130833	77/320 (24%)
		MDH_glyoxysomal_mitochondrial	36..332	CDD:133422	77/320 (24%)
LDHAL6B	NP_149972.1	LDH_1	68..376	CDD:133429	80/330 (24%)
		L-LDH-NAD	74..374	CDD:273796	77/323 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0039
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810