Protein Alignment CG10748 and MDH2

DIOPT Version :10

• Sequence 1: NP_648615.1
• Gene: CG10748 / 39469
• FlyBaseID: FBgn0036327
• Length: 349
• Species: Drosophila melanogaster
• Sequence 2: NP_014515.2
• Gene: MDH2 / 853994
• SGDID: S000005486
• Length: 377
• Species: Saccharomyces cerevisiae
• Alignment Length: 370
• Identity: 128/370 - (34%)
• Similarity: 190/370 - (51%)
• Gaps: 73/370 - (19%)

  Fly    22 TLKVAVVGAGGGIGQPLSLLLR-----------RCPGIDELALHDLSE--MKGIATDLSHISQTG 73
            :||:|::||.|||||.|||||:           |......|||:|:::  :.|:..|||||....
Yeast    13 SLKIAILGAAGGIGQSLSLLLKAQLQYQLKESNRSVTHIHLALYDVNQEAINGVTADLSHIDTPI 77

  Fly    74 KVIGFTGEKELESAVSGADVVVVAAGMPRLPGMQRDHLMAANGNVAVKVATAISNAS--PRAHLA 136
            .|...:....:|:.:..|.:||:.||:||.|||.||.|...|..:..::..:|:...  .:..:.
Yeast    78 SVSSHSPAGGIENCLHNASIVVIPAGVPRKPGMTRDDLFNVNAGIISQLGDSIAECCDLSKVFVL 142

  Fly   137 FITNPVNMIVPA-AAEVLMAH----GTFDSRRLFGITTLDVVRSKKFIGD---------SMNISP 187
            .|:||||.:||. .:.:|..|    .:...||:.|:|.||:||:..|:.:         .:|..|
Yeast   143 VISNPVNSLVPVMVSNILKNHPQSRNSGIERRIMGVTKLDIVRASTFLREINIESGLTPRVNSMP 207

  Fly   188 DDVNIPVIGGHAGITILPLISQCQPIYRCDLQEIQNLTHRIQEAGTEVVNAKAGKGSATLSMAYA 252
            |   :||||||:|.||:||.||...:.|.:..:::.|.||:|..|.|||.||.||||||||||:|
Yeast   208 D---VPVIGGHSGETIIPLFSQSNFLSRLNEDQLKYLIHRVQYGGDEVVKAKNGKGSATLSMAHA 269

  Fly   253 G----ATFVNSLLRGI--------------------AGQDGLIECAFVASKLTD-APFFASPLEL 292
            |    ..||:.||..|                    .|.|.|:       .|.| |.:||.||.:
Yeast   270 GYKCVVQFVSLLLGNIEQIHGTYYVPLKDANNFPIAPGADQLL-------PLVDGADYFAIPLTI 327

  Fly   293 GKDGIK--RYIPLPQMSDYEKEALEKLLPI----LRQNADEGVNF 331
            ...|:.  .|..:.:|:|.|:   .::|||    |::|.|:|:.|
Yeast   328 TTKGVSYVDYDIVNRMNDMER---NQMLPICVSQLKKNIDKGLEF 369

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10748	NP_648615.1	MDH_glyoxysomal_mitochondrial	36..332	CDD:133422	119/356 (33%)
MDH2	NP_014515.2	MDH_euk_gproteo	15..372	CDD:130833	127/368 (35%)