Protein Alignment CG10748 and MDH1

DIOPT Version :10

• Sequence 1: NP_648615.1
• Gene: CG10748 / 39469
• FlyBaseID: FBgn0036327
• Length: 349
• Species: Drosophila melanogaster
• Sequence 2: NP_012838.1
• Gene: MDH1 / 853777
• SGDID: S000001568
• Length: 334
• Species: Saccharomyces cerevisiae
• Alignment Length: 330
• Identity: 154/330 - (46%)
• Similarity: 209/330 - (63%)
• Gaps: 6/330 - (1%)

  Fly     7 LKSLAKPATWGVVVRTLKVAVVGAGGGIGQPLSLLLRRCPGIDELALHDLSEMKGIATDLSHISQ 71
            |..:||.|....|....||.|:||||||||||||||:....:.:|.|:||...||:|||||||..
Yeast     2 LSRVAKRAFSSTVANPYKVTVLGAGGGIGQPLSLLLKLNHKVTDLRLYDLKGAKGVATDLSHIPT 66

  Fly    72 TGKVIGFTGEKE--LESAVSGADVVVVAAGMPRLPGMQRDHLMAANGNVAVKVATAISNASPRAH 134
            ...|.|||.|:.  |.:|:...|:|::.||:||.|||.||.|.|.|.::...:|.|.:.::|.|.
Yeast    67 NSVVKGFTPEEPDGLNNALKDTDMVLIPAGVPRKPGMTRDDLFAINASIVRDLAAATAESAPNAA 131

  Fly   135 LAFITNPVNMIVPAAAEVLMAHGTFDSRRLFGITTLDVVRSKKFIGDSMNISPDDVNIPVIGGHA 199
            :..|:||||..||..|:||...|.::.::|||:||||.:|:.:||.:..|..|....:.|||||:
Yeast   132 ILVISNPVNSTVPIVAQVLKNKGVYNPKKLFGVTTLDSIRAARFISEVENTDPTQERVNVIGGHS 196

  Fly   200 GITILPLISQCQPIYRCDLQEIQNLTHRIQEAGTEVVNAKAGKGSATLSMAYAGATFVNSLLRGI 264
            ||||:|||||.......| .:...|.||||..|.|||.||.|.||||||||:|||.|.|::|.|.
Yeast   197 GITIIPLISQTNHKLMSD-DKRHELIHRIQFGGDEVVKAKNGAGSATLSMAHAGAKFANAVLSGF 260

  Fly   265 AGQDGLIECAFVASKLTDA---PFFASPLELGKDGIKRYIPLPQMSDYEKEALEKLLPILRQNAD 326
            .|:..:||.:||.|.|..:   .|||||:.||.|||::..|:.::|..|:|.|:|....|::|.:
Yeast   261 KGERDVIEPSFVDSPLFKSEGIEFFASPVTLGPDGIEKIHPIGELSSEEEEMLQKCKETLKKNIE 325

  Fly   327 EGVNF 331
            :||||
Yeast   326 KGVNF 330

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10748	NP_648615.1	MDH_glyoxysomal_mitochondrial	36..332	CDD:133422	139/301 (46%)
MDH1	NP_012838.1	MDH_glyoxysomal_mitochondrial	18..331	CDD:133422	149/314 (47%)