DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10748 and Uevld

DIOPT Version :9

Sequence 1:	NP_648615.1	Gene:	CG10748 / 39469	FlyBaseID:	FBgn0036327	Length:	349	Species:	Drosophila melanogaster
Sequence 2:	XP_008757683.1	Gene:	Uevld / 691172	RGDID:	1587416	Length:	470	Species:	Rattus norvegicus

Alignment Length:	313	Identity:	69/313 - (22%)
Similarity:	116/313 - (37%)	Gaps:	62/313 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 KVAVVGAGG-GIGQPLSLLLRRCPGI-DELALHDLSEMKGIAT-DLSHISQTGKVIGFTGEKELE 85
            |:.|||:|. ||...|::..:   || |:|.|.|||:.....| ||...:.....|    .|:|.
  Rat   184 KITVVGSGDLGIACTLAISAK---GIADKLLLLDLSDGTNQGTMDLDIFNLPNVEI----SKDLS 241

  Fly    86 SAVSGADVVVVAAGMPRLPGMQRDHLMAANGNVAV--KVATAISNASPRAHLAFITNPVNMIVPA 148
            ::.....|:..|..:    |....:|.|...||.:  .:..|:.:.|..|.|...:.||.::
  Rat   242 ASAHSKVVIFTANSL----GGSESYLHAVQSNVDMFRALVPALGHYSQHAVLLVASQPVEIM--- 299

  Fly   149 AAEVLMAHGTFDSRRLFGI-TTLDVVRSKKFIGDSMNISPDDVNIPVIG-----------GHAGI 201
             :.|.....||.:.|:.|| ..||..|.:..|...:........:.|:|           |..|:
  Rat   300 -SYVTWKLSTFPAARVMGIGCNLDSQRLQYIISSVLKAQTSGKEVWVVGEQGENKVCSWSGQDGV 363

  Fly   202 ----TILPLISQCQPIYRCDLQEIQNLTHRIQEAGTEVVNAKAGKGSATLSMAYAGATFVNSLLR 262
                :...|.|:...:.:...|...::...:.:....::|.|....|            |::|.:
  Rat   364 MSPSSQAQLSSRAMGLLKVKGQRSWSVGLSVADLLDTIINNKKKVHS------------VSTLAK 416

  Fly   263 GIAGQDGLIECAFVASKLTDAPFFASPLELGKDGIKRYIPLPQMSDYEKEALE 315
            |..|.|..:             |.:.|..||..|:...:. ....|...|||:
  Rat   417 GYYGLDNEV-------------FLSLPCILGTSGVSEVLK-TAAEDAVTEALQ 455

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10748	NP_648615.1	MDH_euk_gproteo	36..333	CDD:130833	62/300 (21%)
CG10748	NP_648615.1	MDH_glyoxysomal_mitochondrial	36..332	CDD:133422	62/300 (21%)
Uevld	XP_008757683.1	UEV	21..138	CDD:283415
		NADB_Rossmann	180..467	CDD:304358	69/313 (22%)
		L-LDH-NAD	187..461	CDD:273796	68/310 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0039
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810