Protein Alignment CG10748 and UEVLD

DIOPT Version :10

• Sequence 1: NP_648615.1
• Gene: CG10748 / 39469
• FlyBaseID: FBgn0036327
• Length: 349
• Species: Drosophila melanogaster
• Sequence 2: NP_001035787.1
• Gene: UEVLD / 55293
• HGNCID: 30866
• Length: 471
• Species: Homo sapiens
• Alignment Length: 298
• Identity: 67/298 - (22%)
• Similarity: 113/298 - (37%)
• Gaps: 31/298 - (10%)

  Fly    24 KVAVVGAGGGIGQPLSLLLRRCPGIDELALHDLSE-MKGIATDLSHISQTGKVIGFTGEKELESA 87
            |:.||| ||.:|...:|.:......|.|.|.|||| .||...||...:.....|    .|:|.::
Human   184 KITVVG-GGELGIACTLAISAKGIADRLVLLDLSEGTKGATMDLEIFNLPNVEI----SKDLSAS 243

  Fly    88 VSGADVVVVAAGMPRLPGMQRDHLMAANGNVAV--KVATAISNASPRAHLAFITNPVNMIVPAAA 150
            .....|:.....:    |..:.:|.....||.:  .:..|:.:.|..:.|...:.||.::    .
Human   244 AHSKVVIFTVNSL----GSSQSYLDVVQSNVDMFRALVPALGHYSQHSVLLVASQPVEIM----T 300

  Fly   151 EVLMAHGTFDSRRLFGI-TTLDVVRSKKFIGDSMNISPDDVNIPVIGGHAGITILPLISQCQPIY 214
            .|.....||.:.|:.|| ..||..|.:..|.:.:........:.|||......:|....|
Human   301 YVTWKLSTFPANRVIGIGCNLDSQRLQYIITNVLKAQTSGKEVWVIGEQGEDKVLTWSGQ----- 360

  Fly   215 RCDLQEIQNLTHRIQ--EAGTEVVNAKAGKGSATLSMAYAGATFVNSLLRGIAGQDGLIECAFVA 277
                :|:.:.|.::|  ....|::..   ||..:.|:..:.|..|:|::........:...|...
Human   361 ----EEVVSHTSQVQLSNRAMELLRV---KGQRSWSVGLSVADMVDSIVNNKKKVHSVSALAKGY 418

  Fly   278 SKLTDAPFFASPLELGKDGIKRYIPLPQMSDYEKEALE 315
            ..:....|.:.|..||.:|:...|......|...|.|:
Human   419 YDINSEVFLSLPCILGTNGVSEVIKTTLKEDTVTEKLQ 456

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10748	NP_648615.1	MDH_glyoxysomal_mitochondrial	36..332	CDD:133422	60/286 (21%)
UEVLD	NP_001035787.1	UEV	21..138	CDD:399041
		LDH_1	180..468	CDD:133429	67/298 (22%)