Protein Alignment CG10748 and mdh1

DIOPT Version :10

• Sequence 1: NP_648615.1
• Gene: CG10748 / 39469
• FlyBaseID: FBgn0036327
• Length: 349
• Species: Drosophila melanogaster
• Sequence 2: NP_001303830.1
• Gene: mdh1 / 448318
• XenbaseID: XB-GENE-484872
• Length: 353
• Species: Xenopus tropicalis
• Alignment Length: 345
• Identity: 79/345 - (22%)
• Similarity: 139/345 - (40%)
• Gaps: 55/345 - (15%)

  Fly    23 LKVAVVGAGG----------------GIGQPLSLLLRRCPGIDELALHDLSEMKGIATDLSH--I 69
            :||.|.||.|                |..|||.|:|     :|...:  ::.::|:..:|..  :
 Frog     5 VKVLVTGAAGQIAYSLLYGIAKGDVFGKDQPLILVL-----LDITPM--MTVLEGVVMELQDCAL 62

  Fly    70 SQTGKVIGFTGEKELESAVSGADVVVVAAGMPRLPGMQRDHLMAANGNVAVKVATAISNASPRA- 133
            ....:||  ..:|| :.|....||.::...|||..||:|..|:.||..:......|::..|.::
 Frog    63 PLLKEVI--ATDKE-DVAFKDLDVAILVGSMPRREGMERKDLLKANVKIFKSQGAALNKYSKKSV 124

  Fly   134 HLAFITNPVNMIVPAAAEVLMAHGTFDSRRLFGITTLDVVRSKKFIGDSMNISPDDVNIPVIGGH 198
            .:..:.||.|.....|   :.:..:........:|.||..|:|..|...:|::.|||...:|.|:
 Frog   125 KVIVVGNPANTNCLTA---MKSAPSIPKENFSCLTRLDHNRAKGQIALKLNVASDDVKNVIIWGN 186

  Fly   199 AGITILPLISQC------------QPIYRCDLQEIQNLTHRIQEAGTEVVNAKAGKGSATLSMAY 251
            ...|..|..|..            :.:...|..:.:.:| .:|:.|..|:  ||.|.|:.:|.|.
 Frog   187 HSSTQYPDASHATVNLQGKDVGAFEAVKNDDWLKGEFIT-TVQQRGAAVI--KARKLSSAMSAAK 248

  Fly   252 AGATFVNSLLRGIAGQDGLIECAFVASK-----LTDAPFFASPLELGKDGIKRYIPLPQMSDYEK 311
            |....|..:..|.  .||......|.|.     :.:...::.||.:.....|....|| ::|:.:
 Frog   249 AICDHVRDIWFGT--PDGQFVSMGVISDGNSYGIPEDLMYSFPLTIKNKTWKIVEGLP-INDFSR 310

  Fly   312 EALEKLLPILRQNADEGVNF 331
            |.::.....|.:..:..:.|
 Frog   311 EKMDLTAKELHEEKETALEF 330

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10748	NP_648615.1	MDH_glyoxysomal_mitochondrial	36..332	CDD:133422	72/316 (23%)
mdh1	NP_001303830.1	MDH_cytoplasmic_cytosolic	3..328	CDD:133421	78/341 (23%)
		PTS1	351..353