DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG10748 and uevld

DIOPT Version :9

Sequence 1:	NP_648615.1	Gene:	CG10748 / 39469	FlyBaseID:	FBgn0036327	Length:	349	Species:	Drosophila melanogaster
Sequence 2:	NP_001003619.1	Gene:	uevld / 445225	ZFINID:	ZDB-GENE-040801-138	Length:	471	Species:	Danio rerio

Alignment Length:	306	Identity:	74/306 - (24%)
Similarity:	127/306 - (41%)	Gaps:	68/306 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 LKVAVVGAGG-GIGQPLSLLLRRCPGIDELALHDLSE--MKGIATDLSHISQTGKVIGFTGEKEL 84
            :||:|:|.|. ||...||::.:.|  :|:|.|.|:.|  .||...||...|.....:    .|:|
Zfish   175 VKVSVIGGGDLGIAAVLSIMAKSC--VDKLVLIDIPENSTKGGTMDLEIFSLPKVEV----SKDL 233

  Fly    85 ESAVSGADVVVVAAGMPRLPGMQRDHLMAANGNVAV--KVATAISNASPRAHLAFITNPVNMIVP 147
             ||.:|:.|:|:.|   .....::.:|.....||.:  .:...::..||.|.|...:.||:::..
Zfish   234 -SASAGSKVLVITA---NAWSDEQSYLSVVQTNVDMYRGIIPRLAQLSPNAVLVIASQPVDVMTH 294

  Fly   148 AA--------AEVLMAHGTFDSRRLFGITTLDVVRSKK-----FIGDSMNISPDDVNIPVIGGHA 199
            .|        .:|:......||:||..|..:.:|.:..     .||:   :|.:.|   .:.|:.
Zfish   295 VAWRQSHLLPTQVIGVGCNLDSQRLSHIINISLVANNTGKQAWVIGE---LSENKV---AVWGNM 353

  Fly   200 GITILPLISQCQPIYRCDLQEIQNLTHRIQEAGTEVVNAKAGKGSATLSMAYAGATF-------- 256
            |    |...|.|.     |..:.|.|..:.:...|::..: |:.|.::.::.|..|.
Zfish   354 G----PGTDQLQA-----LTPVSNSTKPLMDRAFEMIKGR-GQRSWSVGLSIADITHSIVTNQKK 408

  Fly   257 ---VNSLLRGIAGQDGLIECAFVASKLTDAPFFASPLELGKDGIKR 299
               |.:|..|..|         :.||:    |.:.|..||:.|..|
Zfish   409 VHSVTTLAEGWGG---------IGSKV----FLSLPCILGETGSTR 441

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10748	NP_648615.1	MDH_euk_gproteo	36..333	CDD:130833	67/292 (23%)
CG10748	NP_648615.1	MDH_glyoxysomal_mitochondrial	36..332	CDD:133422	67/292 (23%)
uevld	NP_001003619.1	UEV	21..139	CDD:283415
		LDH_1	172..468	CDD:133429	74/306 (24%)
		L-LDH-NAD	179..460	CDD:273796	72/302 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0039
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810