Protein Alignment CG10748 and LDHC

DIOPT Version :9

• Sequence 1: NP_648615.1
• Gene: CG10748 / 39469
• FlyBaseID: FBgn0036327
• Length: 349
• Species: Drosophila melanogaster
• Sequence 2: NP_002292.1
• Gene: LDHC / 3948
• HGNCID: 6544
• Length: 332
• Species: Homo sapiens
• Alignment Length: 325
• Identity: 78/325 - (24%)
• Similarity: 140/325 - (43%)
• Gaps: 61/325 - (18%)

  Fly    24 KVAVVGAGG-GIGQPLSLLLRRCPGIDELALHD--LSEMKGIATDLSHIS---QTGKVIGFTGEK 82
            |:.:||.|. |:...:|:||:..  .|||||.|  |.::||...||.|.|   .|.|:   |..|
Human    22 KITIVGTGAVGMACAISILLKDL--ADELALVDVALDKLKGEMMDLQHGSLFFSTSKI---TSGK 81

  Fly    83 ELESAVSGADVVVVAAGMPRLPGMQRDHLMAANGNVAVKVATAISNASPRAHLAFITNPVNMIVP 147
            :. |..:.:.:|:|.||..:..|..|..|:..|..:...:..||.:.||...:..::|||:::..
Human    82 DY-SVSANSRIVIVTAGARQQEGETRLALVQRNVAIMKSIIPAIVHYSPDCKILVVSNPVDILTY 145

  Fly   148 AAAEVLMAHGTFDSRRLFGITTLDVVRSKKFIGDSMNISPDDVNIPVIGGH-------------A 199
            ...::   .|...:|.:.....||..|.:..||:.:.:.|...:..:||.|             |
Human   146 IVWKI---SGLPVTRVIGSGCNLDSARFRYLIGEKLGVHPTSCHGWIIGEHGDSSVPLWSGVNVA 207

  Fly   200 GI---TILPLISQCQPIYRCDLQEIQNLTHRIQEAGTEVVNAKAGKGSATLSMAYAGATFVNSLL 261
            |:   |:.|.:..     ..|.:..:|:..::.::..|::..   ||..:.::..:....|.|:|
Human   208 GVALKTLDPKLGT-----DSDKEHWKNIHKQVIQSAYEIIKL---KGYTSWAIGLSVMDLVGSIL 264

  Fly   262 RG----------IAGQDGLIECAFVASKLTDAPFFASPLELGKDGIKRYIPLPQMSDYEKEALEK 316
            :.          :.|..|:.|          ..|.:.|..||::|:...:.:...|  |:|||.|
Human   265 KNLRRVHPVSTMVKGLYGIKE----------ELFLSIPCVLGRNGVSDVVKINLNS--EEEALFK 317

  Fly   317  316
            Human   318  317

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10748	NP_648615.1	MDH_euk_gproteo	36..333	CDD:130833	73/312 (23%)
		MDH_glyoxysomal_mitochondrial	36..332	CDD:133422	73/312 (23%)
LDHC	NP_002292.1	LDH_1	18..329	CDD:133429	78/325 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0039
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810